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A biophysical model is a simulation of a biological system using mathematical formalizations of the physical properties of that system. Such models can be used to predict the influence of biological and physical factors on complex systems.
“Visual performance might vary during natural behaviour such as walking. Here, the authors use wireless virtual reality to show that oscillations in performance on a visual detection task were systematically linked to the phase of the stride cycle.”
Using data-driven models of human neurons and microcircuits, the authors tested in-silico a compound for treating depression via boosting cell-specific inhibition, and identified EEG biomarker candidates for monitoring treatment efficacy.
The neural mechanisms that give rise to aperiodic EEG signals remains unclear. Here the authors characterize EEG signals generated by neural processes other than brain rhythms, demonstrating that certain drugs alter EEG signals in ways that confound traditional interpretation.
A new study examines thalamic innervation of cortical layer 2/3 pyramidal neurons and models how this thalamic connectivity affects visual responses in these cells.
