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Biophotonics is the study of optical processes in biological systems, both those that occur naturally and in bioengineered materials. A particularly important aspect of this field is imaging and sensing cells and tissue. This includes injecting fluorescent markers into a biological system to track cell dynamics and drug delivery.
Accessing multi-angle views of organoids is important for biology and oncology. The authors propose ultrasound-induced reorientation for multi-angle optical coherence tomography, using a 3D-printed acoustic trap to levitate and rotate samples with a model-based algorithm for reconstruction.
A time-domain excitation strategy for stimulated Raman scattering was achieved by manipulating vibrational wave packet interference. The new method enables simultaneous sub-mM level sensitivity and natural-linewidth-limit Raman spectra.
Current imaging flow cytometry approaches remain limited in their ability to reveal subcellular information with high-resolution and instrumental simplicity. Here, the authors present a light-field flow cytometer capable of high-content, multi-color imaging of cells with high-resolution in 3D.
A pioneer of DNA nanotechnology, Prof. Laura Na Liu from the University of Stuttgart in Germany, has been working at the interface, where nanophotonics meets biology and chemistry.
Trojan beams, which are optical counterparts of Trojan asteroids that maintain stable orbits alongside planets, have been successfully showcased in experiments, opening up possibilities for transporting light in unconventional settings.
Three-dimensional photoacoustic tomography synchronized with an electrocardiogram provides highly resolved images of a beating heart with optical absorption contrast and enables investigation of cardiovascular diseases in animal models.