Bionanoelectronics articles from across Nature Portfolio

A flexible, biodegradable and self-powered electronic bandage is designed to deliver dual-mode electrical stimulation, which can synergistically accelerate local intestinal wound healing. This approach also shows promise for reducing postoperative complications and could have broad potential for application in other tissues and organs.

The utility of wet-tissue adhesives has been impeded by the suboptimal adhesive strength. Here the authors report a composite patch integrated with BP nanosheets that improve the wet-tissue adhesion by enhancing the water absorption and mechanical properties of the patch and demonstrate the uses of the patch in hemostasis, physical-activity monitoring and tumour-recurrence prevention.

Interfacing living systems with electronics for biosensing and biocomputing applications is challenging. Here, Gao et al. present hybrid transistors with electroactive bacteria capable of extracellular electron transfer, enabling transduction of biological computations to electrical readouts.

Here, the authors combined and synchronized single-cell nanoindentation, electrophysiology and functional fluorescence imaging to evaluate the responses of neuronal networks to mechanical stimuli with piconewton force sensitivity and nanometre precision, enabling the exploration of nanomechanobiology and manipulation of neuronal systems.

Resolving interactions of negligibly charged or neutral small molecules with their binding partners in a label-free manner is challenging. Here the authors present a single-molecule carbon-nanotube biosensor device for capturing aptamer–neurotransmitter kinetics at high temporal resolution, uncovering four-state structural transitions.

Electrodes available for deep brain recording and stimulation have a number of limitations. Here the authors describe a thin-film depth electrode that may offer improved spatial and temporal resolution for recording brain activity.

Bidirectional neural interface electronic devices offer therapeutic options. Here, the authors present wafer-scale fabrication of flexible nanoporous graphene-based implantable microelectrode arrays with low impedance and high charge injection for in vivo brain recording and nerve stimulation.

A flexible, biodegradable and self-powered electronic bandage is designed to deliver dual-mode electrical stimulation, which can synergistically accelerate local intestinal wound healing. This approach also shows promise for reducing postoperative complications and could have broad potential for application in other tissues and organs.

Using fluorinated elastomers in the fabrication of soft neural probes is shown to enhance spatiotemporal recording capability at single-neuron resolution within the central nervous system of rodents. Other soft encapsulation materials could be similarly engineered for high-resolution, long-lasting bioelectronics.

Miniaturized power sources consisting of a few droplets can generate enough power to modulate neuronal activity.

An article in Science reports a co-polymer with both semiconducting and adhesive properties, which can effectively stick an organic electrochemical transistor (OECT)-based sensor to living tissues.