Biomaterials – cells

Latest Research and Reviews

News and Comment

  • News and Views |

    Over-expression of a transcriptional factor, Alx3, has been shown to revitalize the regenerative capacity of adult progenitor cells to promote enhanced stromal vascularization and formation of parenchymal dental pulp tissue in vivo.

    • Sarah E. Millar
    Nature Materials 18, 530-531
  • News and Views |

    Blocking the growth of new blood vessels has been shown to alter fibrosis in livers in a disease stage-specific manner. In vitro models of fibrosis were developed to understand this process, highlighting the role of environmental mechanics.

    • Geoffrey C. Gurtner
    •  & Jagannath Padmanabhan
    Nature Materials 16, 1176-1177
  • Editorial |

    As the role of biophysical cues in regulating cell behaviour is increasingly understood, more evidence in the field of bioengineering indicates how such signals can affect cells and tissues.

    Nature Materials 16, 1163
  • News and Views |

    The influence of matrix stiffness and degradation on neural progenitor cell stemness was investigated in a three-dimensional culture system, highlighting the role of remodelling in enhancing cell-to-cell interaction and ultimately maintaining neural stemness.

    • Phillip H. Kang
    • , Sanjay Kumar
    •  & David V. Schaffer
    Nature Materials 16, 1174-1176
  • News and Views |

    Cysts were generated from organoids in vitro and the removal of adherent cues was shown to play a key role in polycystic kidney disease progression. These cysts resembled those of diseased tissue phenotypically and were capable of remodelling their microenvironment.

    • Paola Romagnani
    Nature Materials 16, 1058-1059