Barrett oesophagus

Definition

Barrett oesophagus is a condition in which the squamous epithelium of the distal oesophagus is replaced by columnar epithelium via metaplasia, in this case intestinal metaplasia (goblet cells present). Barrett oesophagus is a precursor to oesophageal adenocarcinoma. The principal cause of Barrett oesophagus is chronic acid reflux.

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