Bacterial toxins

Bacterial toxins are toxic substances that are produced and released by bacteria to target other bacterial or host cells. Bacteria often have antitoxins to avoid the deleterious effects of toxins.

Latest Research and Reviews

News and Comment

  • News and Views |

    It is now clear that key autophagy proteins possess alternative functions, distinct from their conventional roles in autophagy. Adding to this emerging field, a new study shows how ATG16L1 acts to promote plasma membrane repair following damage by pore-forming bacteria.

    • Oliver Florey
    Nature Microbiology 3, 1334-1335
  • News and Views |

    Protein translocation across bacterial membranes can take many routes through dedicated transport machines. A new study finds that Salmonella Typhi utilizes a distinct pathway to translocate typhoid toxin across the peptidoglycan layer and prime the bacterium for host intoxication.

    • Anastassios Economou
    Nature Microbiology 3, 1192-1193
  • News and Views |

    Genetic integration of a humanized chemotaxis receptor unexpectedly reveals that a widely expressed immune protein is targeted by Staphylococcus aureus Panton–Valentine leukocidin in a novel way, changing our fundamental understanding of toxin–receptor biology and host–pathogen interaction.

    • Brandon Lee
    •  & Juliane Bubeck Wardenburg
    Nature Microbiology 3, 644-645
  • News and Views |

    Bacteria can compete in the environment using antibacterial type VI secretion systems. A recent study reveals that the simultaneous deployment of an arsenal of different toxins promotes both synergy between those toxins and an optimized answer in the face of inconstant environments.

    • Sophie Bleves
    •  & Benjamin Berni
    Nature Microbiology 3, 394-395