Bacterial secretion

Bacterial secretion is the process by which bacteria release substances to their surroundings, including other cells. Bacteria achieve this using dedicated secretion systems that transport molecules – such as factors involved in bacterial pathogenesism, so called effectors – across the cell wall.

Latest Research and Reviews

News and Comment

  • News and Views |

    Bacteria employ a specialized weapon known as the type VI secretion system to defend themselves from competing organisms. A new study reveals the molecular architecture of the type VI secretion system and highlights conserved mechanistic similarities with contractile phage tails.

    • Alan R. Davidson
    •  & Karen L. Maxwell
    Nature Microbiology 3, 1330-1331
  • News and Views |

    Protein translocation across bacterial membranes can take many routes through dedicated transport machines. A new study finds that Salmonella Typhi utilizes a distinct pathway to translocate typhoid toxin across the peptidoglycan layer and prime the bacterium for host intoxication.

    • Anastassios Economou
    Nature Microbiology 3, 1192-1193
  • News and Views |

    A powerful in vivo biotinylation approach identifies TagA as a binding partner of TssA, a central regulator of the assembly of the type VI secretion system (T6SS). TagA terminates assembly of the T6SS tail and tethers it to the membrane, acting as a crossbow latch that allows for efficient firing.

    • Olivera Francetic
    Nature Microbiology 3, 1190-1191