Bacterial pathogenesis

Bacterial pathogenesis is the process by which bacteria infect and cause disease in a host. Not all bacteria are pathogens and have the ability for pathogenesis (also known as virulence).

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  • News and Views |

    Biofilms are communities of bacteria that accumulate on surfaces such as replacement joints or intravenous catheters. By silencing a key communication system, Staphylococcus aureus builds tightly packed biofilms that can withstand attack by host immune cells.

    • Andrew M. Edwards
    Nature Microbiology 4, 1073-1074
  • Research Highlights |

    This study found that coagulase-negative staphylococci found on human skin inhibit Staphylococcus aureus quorum sensing and may influence the pathophysiology of S. aureus-associated atopic dermatitis.

    • Ashley York
  • Research Highlights |

    Two studies describe how a commensal can either protect against or promote colitis, and a third study shows how colitis can affect the disease severity of a subsequent infection.

    • Andrea Du Toit
  • Research Highlights |

    This study reports that the intracellular c-di-GMP levels are reduced in Salmonella enterica subsp. enterica serovar Typhimurium during infection of macrophages to promote survival.

    • Andrea Du Toit