Bacterial host response

The bacterial host response is the process by which the host interacts with, and responds to, bacteria that colonize or infect it. This includes defense mechanisms such as the immune response.

Latest Research and Reviews

News and Comment

  • News and Views |

    It is now clear that key autophagy proteins possess alternative functions, distinct from their conventional roles in autophagy. Adding to this emerging field, a new study shows how ATG16L1 acts to promote plasma membrane repair following damage by pore-forming bacteria.

    • Oliver Florey
    Nature Microbiology 3, 1334-1335
  • News and Views |

    The discovery of CD153 as a novel driver of T-cell-mediated host defence against Mycobacterium tuberculosis infection advances our understanding of the requirements for protective immunity. Future investigation of CD153 as a potential correlate of tuberculosis immunity could open new avenues for vaccine design.

    • Sara B. Cohen
    •  & Kevin B. Urdahl
    Nature Microbiology 3, 1194-1195
  • News and Views |

    How the immune system handles the relentless presence of commensal bacteria is an area of great interest. Here, researchers describe a role for autophagy in mediating tolerance to the microbiota, the absence of which can impart beneficial resistance to infection but also possible detriment in the form of autoimmunity.

    • Jennifer Martinez
    Nature Microbiology 3, 1080-1081