Bacterial genomics articles from across Nature Portfolio

In hospitals, surfaces present as a reservoir for bacteria pathogens, potentially leading to nosocomial infections. In this work, authors aim to profile extended-spectrum β lactamase- and carbapenemase-carrying bacterial species colonising neonatal hospital wards and causing neonatal sepsis.

Mycobacterium abscessus is considered an emerging pathogen, given its prevalence in patients with pulmonary diseases, such as cystic fibrosis. Here, authors perform a genomic analysis on sequential isolates obtained from patients with persistent infections of M. abscessus.

A study underscores the emergence of a qacA-harbouring multidrug-resistant sequence type 45 methicillin-resistant Staphylococcus aureus lineage, highlighting the potential impact of biocide tolerance on its recent clonal spread in Australia and Asia.

A study reveals that Fusobacterium nucleatum subspecies animalis is bifurcated into two distinct clades, and shows that only one of these dominates the colorectal cancer niche, probably through increased colonization of the human gastrointestinal tract.

Genomic epidemiology of the Yemen cholera outbreak reveals the genetic basis for emergence of multidrug resistance with implications for Vibrio cholerae surveillance and control.

This study reports a bacterial antiphage protein that contains a NACHT domain, which is also found in metazoan proteins that mediate immunity and inflammation.

The Tibetan glacier genome and gene catalog includes 3,241 metagenome-assembled or cultured genomes spanning 30 phyla and over 25 million genes encoding non-redundant proteins. This catalog provides a wealth of resources for archiving glacier microbial diversity and bioprospecting for bioactive compounds, as well as a platform for global comparison of glacier microbiomes.

This study reports the discovery of two new DNA defence modules, termed DdmABC and DdmDE, in Vibrio cholerae.

This month’s Genome Watch highlights how genome and transcriptome sequencing of newly identified endosymbionts helps to connect genetic information to their protective functions.

A whole-genome sequencing study reveals a bottleneck in syphilis spread in the late 1990s followed by global spread.