Bacterial genetics

Bacterial genetics is the study of the mechanisms of heritable information in bacteria, their chromosomes, plasmids, transposons and phages. Techniques that have enabled this discipline are culture in defined media, replica plating, mutagenesis, transformation, conjugation and transduction.

Latest Research and Reviews

News and Comment

  • News and Views |

    Differences in microbial genomes can result in vastly different phenotypes and functions. Consequently, it is critical to understand the genome variations that differentiate microbial strains. Here, we discuss recent exciting advances that enable structural variant measurement, their associated phenotypes and the horizon for future discovery.

    • Matthew G. Durrant
    •  & Ami S. Bhatt
    Nature Microbiology 4, 912-913
  • Research Highlights |

    This study analysed the proportion of uncultured bacteria and archaea globally and found that the majority of environments are dominated by uncultured cells.

    • Ursula Hofer
  • News and Views |

    Widespread use of antibiotics in animals either as growth promoters or for metaphylaxis may drive the spread of clinically relevant drug resistance genes and pathogens. New work uncovers drug resistance gene patterns from livestock across European farms and finds a correlation with agricultural antibiotic use.

    • Timothy R. Walsh
    Nature Microbiology 3, 854-855
  • Editorial |

    Although the spotlight on CRISPR–Cas systems has shone on their immense potential as genome-editing tools, the field’s origins are rooted in the microbiology of phage–bacterium interactions. Furthering our understanding of these processes can uncover more systems and generate new reagents with revolutionary properties.

  • News and Views |

    Genetic integration of a humanized chemotaxis receptor unexpectedly reveals that a widely expressed immune protein is targeted by Staphylococcus aureus Panton–Valentine leukocidin in a novel way, changing our fundamental understanding of toxin–receptor biology and host–pathogen interaction.

    • Brandon Lee
    •  & Juliane Bubeck Wardenburg
    Nature Microbiology 3, 644-645