Autoinflammatory syndrome refers to a disorder characterized by recurrent episodes of systemic inflammation in the apparent absence of pathogens, autoantibodies or self-reactive lymphocytes. These disorders are caused by dysfunction of the innate immune system. Examples of such disorders include Behçet's disease, Familial Mediterranean Fever and Cryopyrin-Associated Periodic Syndrome.
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Research |Nature Immunology 17, 922–929
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News and Views |Nature Reviews Rheumatology 12, 256–258