Archaea are organisms consisting of a single cell without a nucleus and with distinct structural, physiological and evolutionary characteristics. They inhabit a wide range of habitats, including extreme environments. Archaea form one of the three domains of life; the others are bacteria and eukaryotes.

Latest Research and Reviews

  • Reviews |

    Next-generation sequencing has the potential to support public health surveillance systems to improve the early detection of emerging infectious diseases. This Review delineates the role of genomics in rapid outbreak response and the challenges that need to be tackled for genomics-informed pathogen surveillance to become a global reality.

    • Jennifer L. Gardy
    •  & Nicholas J. Loman
  • Research | | open

    Little is known about Marinimicrobia, a group of bacteria that are prevalent in the oceans. Here, the authors study global populations of Marinimicrobia using single-cell genomics, metagenomics and metatranscriptomics, showing potential co-metabolic interactions and participation in the sulfur and nitrogen cycles.

    • Alyse K. Hawley
    • , Masaru K. Nobu
    • , Jody J. Wright
    • , W. Evan Durno
    • , Connor Morgan-Lang
    • , Brent Sage
    • , Patrick Schwientek
    • , Brandon K. Swan
    • , Christian Rinke
    • , Monica Torres-Beltrán
    • , Keith Mewis
    • , Wen-Tso Liu
    • , Ramunas Stepanauskas
    • , Tanja Woyke
    •  & Steven J. Hallam
  • Reviews |

    One of the most prominent features of archaea is the extraordinary diversity of their viruses. In this Review, Prangishvili et al. summarize their morphological diversity, the molecular biology of their life cycles and virus–host interactions, and discuss their evolution and their role in the global virosphere.

    • David Prangishvili
    • , Dennis H. Bamford
    • , Patrick Forterre
    • , Jaime Iranzo
    • , Eugene V. Koonin
    •  & Mart Krupovic
  • Reviews |

    The Archaea was recognized as a third domain of life 40 years ago. In this Review, Eme et al. outline a brief history of the changing shape of the tree of life and examine how the recent discovery of diverse archaeal lineages has changed our understanding of the evolutionary relationships between the three domains of life and the origin of the eukaryotic cell.

    • Laura Eme
    • , Anja Spang
    • , Jonathan Lombard
    • , Courtney W. Stairs
    •  & Thijs J. G. Ettema

News and Comment