Antibiotics

Antibiotics are substances that inhibit the growth of bacteria. They work by killing bacteria or preventing their reproduction, and may be synthesized chemically or by naturally-occurring or engineered organisms.

Latest Research and Reviews

News and Comment

  • Research Highlights |

    This study shows that in the non-growing, antibiotic-tolerant state, Salmonella enterica subsp. enterica serovar Typhimurium actively subverts host cells to promote survival during antibiotic exposure, persistent infections and long-term survival.

    • Andrea Du Toit
  • News and Views |

    The biosynthesis of the pharmacophoric tetrahydropyran of the clinically important antibiotic mupirocin remained enigmatic for a long time. Now, research shows that this ring is formed by a unique epoxidation–epoxide-opening cascade starting from a non-activated alkane.

    • Frank Hahn
    Nature Catalysis 1, 905-906
  • Comments and Opinion |

    Each person’s skin carries a unique population of microbes that might help to protect skin from infection, or increase its vulnerability.

    • Emily Sohn
    Nature 563, S91-S93
  • News and Views |

    In humans, niche-specific gastrointestinal microbiomes influence the colonization success of probiotic microbes. Microbiome reconstitution following antimicrobial perturbation is most successful using preperturbation autofecal microbial transplant.

    • Elze Rackaityte
    •  & Susan V. Lynch
    Nature Medicine 24, 1642-1644