Adherens junctions are cadherin-based adhesive structures that mediate intercellular contacts. They form through the association of cadherins on adjacent cells, which use their intracellular regions to recruit multiprotein complexes that are linked to the actin cytoskeleton. In epithelia they form a continuous adhesion belt, the zonula adherens, which encircles the apicolateral region of interacting cells.
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Research Highlights |Nature Reviews Molecular Cell Biology 16, 578–579
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