Acne vulgaris

Acne vulgaris is skin disease that is characterized by excessive oil production, blackheads, whiteheads, pustules and scarring. It is very common during puberty but it can persist or occur later as well. Genetic, hormonal and infectious factors underlie its pathogenesis.

Latest Research and Reviews

  • Research | | open

    Acne vulgaris is a chronic inflammation of the skin, the genetic basis of which is incompletely understood. Here, Petridis et al. perform GWAS and meta-analysis for acne in 26,722 individuals and identify 12 novel risk loci that implicate structure and maintenance of the skin in severe acne risk.

    • Christos Petridis
    • , Alexander A. Navarini
    • , Nick Dand
    • , Jake Saklatvala
    • , David Baudry
    • , Michael Duckworth
    • , Michael H. Allen
    • , Charles J. Curtis
    • , Sang Hyuck Lee
    • , A. David Burden
    • , Alison Layton
    • , Veronique Bataille
    • , Andrew E. Pink
    • , Anton Alexandroff
    • , Alex Anstey
    • , Jaskiran Azad
    • , Omar Aziz
    • , Nigel Burrows
    • , Aamir Butt
    • , Peter Cartwright
    • , Anna Chapman
    • , Timothy H. Clayton
    • , Sandeep Cliff
    • , Tim Cutler
    • , Brigid Daly
    • , Amrit Darvay
    • , Claudia DeGiovanni
    • , Anthony Downs
    • , Colm Dwyer
    • , John English
    • , Adam Ferguson
    • , Colin Fleming
    • , Elizabeth Fraser-Andrews
    • , Mark Goodfield
    • , Clive E. Grattan
    • , Hartmut Hempel
    • , Sue Hood
    • , Bronwyn Hughes
    • , Evmorfia Ladoyanni
    • , Calum Lyon
    • , Ali Mahmud
    • , Moshin Malik
    • , Eleanor Mallon
    • , Simon Meggitt
    • , Andrew Messenger
    • , Yaaseen Moosa
    • , Stephanie Munn
    • , Anthony Ormerod
    • , Deepak Rallan
    • , Janet Ross
    • , Ingrid Salvary
    • , Rachel Wachsmuth
    • , Shyamal Wahie
    • , Shernaz Walton
    • , Sarah Walsh
    • , Diane Williamson
    • , Carolyn Willis
    • , Isabelle Carlavan
    • , Johannes J. Voegel
    • , Timothy D. Spector
    • , Richard C. Trembath
    • , John A. McGrath
    • , Catherine H. Smith
    • , Jonathan N. Barker
    •  & Michael A. Simpson
  • Reviews |

    Acne vulgaris is a chronic inflammatory disease of the pilosebaceous gland and is among the most common dermatological conditions worldwide. In this Primer, Feldman and colleagues describe the pathophysiology, diagnostic tools and current treatment options for acne and urge for a better recognition of this disease.

    • Sara Moradi Tuchayi
    • , Evgenia Makrantonaki
    • , Ruta Ganceviciene
    • , Clio Dessinioti
    • , Steven R. Feldman
    •  & Christos C. Zouboulis