Big potential in rat pluripotent stem cells
Monya Baker
Rat pluripotent stem cells could bring knock-out rats, reprogramming insights, and a larger menagerie of stem cells.
Published online: 08 January 2009; doi:10.1038/stemcells.2009.10
State of the stem cell
Monya Baker
An overview of the not-so-distant past, and an outlook for the not-so-distant future
Published online: 22 October 2009; doi:10.1038/stemcells.2009.132
RepSox hits a home run
Monya Baker
Small molecule can replace Sox2, c-Myc in reprogramming
Published online: 15 October 2009; doi:10.1038/stemcells.2009.130
Induced pluripotent stem cells, down to one factor
Monya Baker
Human neural stem cells reprogrammed with only OCT4
Published online: 10 September 2009; doi:10.1038/stemcells.2009.117
Full Text - Induced pluripotent stem cells, down to one factor
Stem cells: The highs and lows of pluripotency - pp590 - 591
Mary Muers
Published online: 28 July 2009; doi:10.1038/nrg2650
Full Text - Stem cellsThe highs and lows of pluripotency | PDF (154 KB) - Stem cellsThe highs and lows of pluripotency
p53 prevents pluripotency
Elie Dolgin
The guardian of the genome also blocks reprogramming
Published online: 20 August 2009; doi:10.1038/stemcells.2009.112
iPS cells make mice that make mice
Monya Baker
Years after their derivation, induced pluripotent stem cells pass the most rigorous test of pluripotency
Published online: 06 August 2009; doi:10.1038/stemcells.2009.106
Cell origin and variation in induced pluripotent stem cell lines
Monya Baker
iPS cells from tail-tip fibroblasts tend toward teratomas
Published online: 30 July 2009; doi:10.1038/stemcells.2009.100
Full Text - Cell origin and variation in induced pluripotent stem cell lines
Mice made from induced stem cells
David Cyranoski
Technical feat shows that the different route to stem cells can indeed make a full mammal body.
Published online: 23 July 2009; doi:10.1038/460560a
On your (histone) marks...get set...go!
Mariano Loza Coll
Epigenetic marks for gene activation precede fertilization
Published online: 25 June 2009; doi:10.1038/stemcells.2009.87
Without a trace? PiggyBac-ing toward pluripotency - pp329 - 330
Matthias Stadtfeld & Konrad Hochedlinger
A transposon-based approach has been added to the growing arsenal of technologies to produce transgene-free and potentially safer induced pluripotent stem cells.
doi:10.1038/nmeth0509-329
Full Text - Without a trace? PiggyBac-ing toward pluripotency | PDF (824 KB) - Without a trace? PiggyBac-ing toward pluripotency
Reprogramming to pluripotency without genetic engineering
Monya Baker
Researchers make iPS cells without inserting DNA
Published online: 30 April 2009; doi:10.1038/stemcells.2009.65
Full Text - Reprogramming to pluripotency without genetic engineering
Cloned embryos can't fool a womb
Mariano Loza Coll
The endometrium can differentiate between embryos generated by various technologies
Published online: 30 April 2009; doi:10.1038/stemcells.2009.67
MicroRNAs boost reprogramming, boot out cMyc
Monya Baker
MicroRNAs, along with transcription factors, produce homogenous iPS cell colonies from mouse fibroblasts
Published online: 23 April 2009; doi:10.1038/stemcells.2009.62
Stem cells: Low-risk reprogramming - pp715 - 716
Martin F. Pera
New techniques circumvent a roadblock to the production of embryonicstem-cell-like lines from adult tissue. Such reprogrammed cell lines should be much safer to use for therapy.
Published online: 08 April 2009; doi:10.1038/458715a
Full Text - Stem cellsLow-risk reprogramming | PDF (754 KB) - Stem cellsLow-risk reprogramming
Look now! Human iPS cells with no genetic integration
Monya Baker
Six reprogramming factors in a plasmid reach a holy grail
Published online: 02 April 2009; doi:10.1038/stemcells.2009.51
Full Text - Look now! Human iPS cells with no genetic integration
Cells reprogrammed using only one gene
Monya Baker
Taking neural stem cells to pluripotency with Oct4 alone
Published online: 12 February 2009; doi:10.1038/stemcells.2009.28
Hybrid embryos fail to live up to stem-cell hopes
Heidi Ledford
Strategy for creating pluripotent cells called into question.
Published online: 03 February 2009; doi:10.1038/457642b
Full Text - Hybrid embryos fail to live up to stem-cell hopes
How the four factors reprogram
Monya Baker
An analysis of when and where pluripotency factors bind indicate that c-Myc shuts down specialization and the remaining three turn on pluripotency
Published online: 29 January 2009; doi:10.1038/stemcells.2009.24
A new pluripotency factor can stand in for two others
Asher Mullard
No need for Klf4 and c-Myc when you reprogramme with Esrrb
Published online: 15 January 2009; doi:10.1038/stemcells.2009.18
Full Text - A new pluripotency factor can stand in for two others
A superficial success
Bryn Nelson
The promise of stem cells in reconstructive surgery has prompted a surge in rejuvenating skin creams that claim to stimulate them. But commercial success says nothing about efficacy
Published online: 15 January 2009; doi:10.1038/stemcells.2008.163
