Stem cell lines make the grade
Simone Alves
Clinical-grade human embryonic stem cell lines generated
Published online: 29 November 2007; doi:10.1038/stemcells.2007.122
Monkey embryonic stem cells cloned
Monya Baker
Attempts in humans already under way
Published online: 21 November 2007; doi:10.1038/stemcells.2007.119
Primate cells cloned by nuclear transfer
Natalie DeWitt
304 monkey oocytes yield 35 blastocysts, 2 cell lines
Published online: 21 November 2007; doi:10.1038/stemcells.2007.118
New genetic engineering tools for human embryonic stem cells
Elie Dolgin
Phage and zinc fingers allow precise genetic tinkering
Published online: 08 November 2007; doi:10.1038/stemcells.2007.115
Full Text - New genetic engineering tools for human embryonic stem cells
Healthy chimeras span species
Elie Dolgin
Embryonic stem cells make interspecies mouse
Published online: 01 November 2007; doi:10.1038/stemcells.2007.111
No role for Oct4 in regenerating adult tissues
Sarah Webb
doi:10.1038/stemcells.2007.103
Many ways to pluripotency - pp1114 - 1116
Robin Lovell-Badge
Stem cells derived from the postimplantation mouse embryo resemble human embryonic stem cells.
doi:10.1038/nbt1007-1114
Full Text - Many ways to pluripotency | PDF (908 KB) - Many ways to pluripotency
Embryonic stem cells make their own niche
Monya Baker
Niches-in-dishes may yield clues to differentiation
Published online: 27 September 2007; doi:10.1038/stemcells.2007.94
Different cell lines, different neurons
Monya Baker
Embryonic stem cells seem preprogrammed to create particular subtypes of cells
Published online: 23 August 2007; doi:10.1038/stemcells.2007.77
Of very young mice and men - pp603
Natalie de Souza
doi:10.1038/nmeth0807-603
Full Text - Of very young mice and men | PDF (96 KB) - Of very young mice and men
Korean stem cells unmasked
Ewen Callaway
doi:10.1038/news070730-9
Activated eggs offer route to stem cells - pp116
David Cyranoski
Technique could sidestep need for viable embryos.
Published online: 11 July 2007; doi:10.1038/448116a
Full Text - Activated eggs offer route to stem cells | PDF (382 KB) - Activated eggs offer route to stem cells
Cooperative study of 59 human embryonic stem cell lines finds reassuring similarity
Monya Baker
Published online: 28 June 2007; doi:10.1038/stemcells.2007.48
Full Text - Cooperative study of 59 human embryonic stem cell lines finds reassuring similarity
Monkey stem cells cloned - pp891
Monya Baker
Advance could renew enthusiasm for the field
Published online: 20 June 2007; doi:10.1038/447891a
Full Text - Monkey stem cells cloned | PDF (197 KB) - Monkey stem cells cloned
Cultured ES cells come unstuck
Natalie DeWitt
A clinically approved kinase inhibitor can stop human ES cells from clumping, and should make them easier to grow.
Published online: 07 June 2007; doi:10.1038/stemcells.2007.1
Parsing pluripotency: the role of Sox2
Natalie DeWitt
Sox2, a protein known to be necessary to keep embryonic stem cells from differentiating, does so by an unexpected mechanism.
Published online: 07 June 2007; doi:10.1038/stemcells.2007.8
Alternative energy for embryonic stem cell research
Markus Grompe
The ethical concerns regarding the destruction of human life outweigh the potential benefits of producing new embryo-derived cell lines
Published online: 11 October 2007; doi:10.1038/stemcells.2007.100
Full Text - Alternative energy for embryonic stem cell research
Animal-human chimeras: Summary of UK Academy of Medical Sciences Report
Natalie DeWitt
Highly varied experiments require case-by-base review.
Published online: 02 August 2007; doi:10.1038/stemcells.2007.67
Full Text - Animal-human chimeras: Summary of UK Academy of Medical Sciences Report
A theological argument for chimeras
Ted Peters
On what theological grounds would one protect the line between species?
Published online: 14 June 2007; doi:10.1038/stemcells.2007.31
Scientific definition by political request
Monya Baker
The NIH must set criteria for pluripotency in human cells
Published online: 17 October 2007; doi:10.1038/stemcells.2007.102
Stem cells by any other name
Monya Baker
The US registry formerly known as 'embryonic'.
Published online: 11 October 2007; doi:10.1038/stemcells.2007.101
Irrational Japanese regulations hinder human embryonic stem cell research
Norio Nakatsuji
Although the principles regulating the research are sound, their implementation is onerous.
Published online: 09 August 2007; doi:10.1038/stemcells.2007.66
Full Text - Irrational Japanese regulations hinder human embryonic stem cell research
Survey: US Couples willing to donate embryos
Monya Baker
Most IVF patients would give embryos for stem cells
Published online: 26 July 2007; doi:10.1038/stemcells.2007.65
Stem cells: Primates join the club - pp485 - 486
Ian Wilmut & Jane Taylor
Researchers have achieved the testing goal of generating embryonic stem cells from the cells of an adult primate. The procedure used could provide insights into a variety of diseases, if it can be applied in humans.
Published online: 21 November 2007; doi:10.1038/450485a
Full Text - Stem cellsPrimates join the club | PDF (235 KB) - Stem cellsPrimates join the club
Fertilized eggs reprogram adult-cell genomes
Monya Baker
Findings that fertilized eggs can be used to clone mice raise an old question: how can a single cell manipulate DNA to support an entire organism's development?
Published online: 07 June 2007; doi:10.1038/stemcells.2007.4
A conversation with Ian Wilmut, Director of the Centre for Regenerative Medicine, University of Edinburgh
Monya Baker
Dolly the sheep came not from the union of sperm and egg but from the mammary cell of one sheep and the unfertilized egg of another. Her birth, more than 10 years ago showed that nuclei from specialized adult cells can be reprogrammed into all the cells of an organism.
Published online: 07 June 2007; doi:10.1038/stemcells.2007.5
From skin cell to stem cell
Monya Baker
Mouse skin cells made pluripotent by genetic modification can give rise to all types of tissue.
Published online: 07 June 2007; doi:10.1038/stemcells.2007.6
Mice cloned using fertilized eggs
Monya Baker
Unfertilized eggs have long been the limiting resource for attempts to make genetically tailored human embryonic stem cells. If a new technique for cloning mice from fertilized eggs works in humans, they might not be necessary.
Published online: 07 June 2007; doi:10.1038/stemcells.2007.7
A conversation with Shinya Yamanaka, Professor at Kyoto University
Monya Baker
A technique to transform specialized cells could pave the way to create patient-specific "embryonic" stem cells, without requiring eggs or embryos.
Published online: 07 June 2007; doi:10.1038/stemcells.2007.9
Full Text - A conversation with Shinya Yamanaka, Professor at Kyoto University
Man or beast? Man and beast!
Ian Wilmut
Scientists should try putting human nuclei into animal eggs. These part-animal cells could produce some of the most powerful tools yet for unravelling human disease. Even if this procedure doesn't lead to embryonic stem cells, the attempt has something to teach us.
Published online: 07 June 2007; doi:10.1038/stemcells.2007.3
Affairs of the heart
Natalie DeWitt
At the NIH meeting on cardiovascular regenerative medicine, researchers debate what cells, if any, can heal.
Published online: 15 November 2007; doi:10.1038/stemcells.2007.114
Japan to ease restrictions on ES cell research
Monya Baker
Published online: 14 June 2007; doi:10.1038/stemcells.2007.34
