Development

Inside the Paper: Rewriting in blood: blood stem cells may have a surprising origin

Natalie DeWitt

A new labeling technique revives an old, discarded theory.

Published online: 21 June 2007; doi:10.1038/stemcells.2007.42

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Stem cell meeting 2007: Routes and roadblocks on the way to cures

Natalie DeWitt

While the basic side of stem cell research is prospering, several talks on translating research to therapy were sobering reminders of the challenges ahead.

Published online: 12 July 2007; doi:10.1038/stemcells.2007.52

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Human–animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate - pp988 - 992

Justin St John & Robin Lovell-Badge

Scientists are seeking permission to generate human embryonic stem cells to study disease by introducing human genetic material into an animal oocyte. This has raised ethical questions that centre on whether the entities being generated are actually human. The answer to these questions will determine how this area of research will be regulated and whether such work will be legal. The function of the extra-nuclear mitochondrial genome lies at the heart of these issues and forms the focus of this commentary.

doi:10.1038/ncb436

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Making healthy mice with two moms

Bryn Nelson

Engineered mice thrive in the absence of paternal imprinting

Published online: 30 August 2007; doi:10.1038/stemcells.2007.80

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