Cancer stem cells

Getting to the stem of chronic myeloid leukaemia - pp341 - 350

Michael Savona & Moshe Talpaz

doi:10.1038/nrc2368

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OncoMed scores drug deal for $1.4 billion with Glaxo

doi:10.1038/451511e

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Stem cell meeting 2008: in with the old, in with the new

Monya Baker & Natalie DeWitt

Although excitement around advances in reprogramming somatic cells shows no signs of abating, new ideas regarding the field are surfacing.

Published online: 17 July 2008; doi:10.1038/stemcells.2008.108

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Leukaemia: A provoking end? - pp407

Nicola McCarthy

doi:10.1038/nrc2412

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Cancer stem cells – old concepts, new insights - pp947 - 958

L Vermeulen, M R Sprick, K Kemper, G Stassi & J P Medema

Published online: 15 February 2008; doi:10.1038/cdd.2008.20

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In Brief - pp411

doi:10.1038/nrc2414

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Cancer and embryonic stem cells share genetic fingerprints

Monya Baker

At least two modules of genes promote stemness

Published online: 17 April 2008; doi:10.1038/stemcells.2008.62

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Skin cancer needs beta-catenin

Monya Baker

Without beta-catenin cancer stem cells no longer support tumours

Published online: 03 April 2008; doi:10.1038/stemcells.2008.57

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Radiation therapy: Sensitizing stem cells - pp246 - 247

Patrick Goymer

doi:10.1038/nrc2358

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Drug makers chase cancer stem cells - pp366 - 367

Charlie Schmidt

doi:10.1038/nbt0408-366c

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BRCA1 and stem cells: tumour typecasting - pp377 - 379

Matthew J. Smalley, Jorge S. Reis-Filho & Alan Ashworth

Phenotypic variation between tumour types is likely to reflect the nature of the cell of origin and the genes involved in pathogenesis. Compared with most sporadic breast cancers, those arising in carriers of BRCA1 mutations usually have distinctive pathological characteristics. A new study suggests that a role for BRCA1 in the determination of stem-cell fate may explain this phenomenon.

doi:10.1038/ncb0408-377

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Cancer and stem cells: Beckman conference

Monya Baker

Cancer cells emerge when checkpoints fail

Published online: 13 March 2008; doi:10.1038/stemcells.2008.47

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Stuck on youth

Jen Middleton

Some cancer stem cells retain an embryonic pathway

Published online: 24 January 2008; doi:10.1038/stemcells.2008.23

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Twins yield leukaemia stem cells

Heidi Ledford

doi:10.1038/news.2008.447

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MicroRNA reins in tumor-initiating cells

Sarah Webb

A microRNA that silences two oncogenes is quiet in cancer stem cells

Published online: 03 January 2008; doi:10.1038/stemcells.2007.137

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Stem cell self-renewal versus differentiation: Tumor suppressor Mei-P26 and miRNAs control the balance - pp713 - 715

Run Shen & Ting Xie

doi:10.1038/cr.2008.79

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Stem cells: MicroRNAs promote differentiation - pp245

Patrick Goymer

doi:10.1038/nrc2357

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