Cancer stem cells

Epigenetic regulation of normal and malignant hematopoiesis - pp6697 - 6714

K L Rice, I Hormaeche & J D Licht

doi:10.1038/sj.onc.1210755

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Leukemia might elbow out blood makers

Monya Baker

A new mouse model helps researchers study human cancer cells

Published online: 01 November 2007; doi:10.1038/stemcells.2007.112

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Cancer stem cells: Underground movement - pp812 - 813

Nicola McCarthy

doi:10.1038/nrc2257

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Making a tumour's bed: glioblastoma stem cells and the vascular niche - pp733 - 736

Richard J. Gilbertson & Jeremy N. Rich

doi:10.1038/nrc2246

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Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis - pp791 - 799

John Stingl & Carlos Caldas

doi:10.1038/nrc2212

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Cancer stem cell sightings and slightings

Bruce Goldman

Experts debate the rarity and relevance of 'tumour-initiating cells'

Published online: 27 September 2007; doi:10.1038/stemcells.2007.93

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Stem cells not all to blame

Monya Baker

Cells driving tumor growth may not be all that rare

Published online: 16 August 2007; doi:10.1038/stemcells.2007.75

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Stem cell meeting 2007: Routes and roadblocks on the way to cures

Natalie DeWitt

While the basic side of stem cell research is prospering, several talks on translating research to therapy were sobering reminders of the challenges ahead.

Published online: 12 July 2007; doi:10.1038/stemcells.2007.52

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Human–animal cytoplasmic hybrid embryos, mitochondria, and an energetic debate - pp988 - 992

Justin St John & Robin Lovell-Badge

Scientists are seeking permission to generate human embryonic stem cells to study disease by introducing human genetic material into an animal oocyte. This has raised ethical questions that centre on whether the entities being generated are actually human. The answer to these questions will determine how this area of research will be regulated and whether such work will be legal. The function of the extra-nuclear mitochondrial genome lies at the heart of these issues and forms the focus of this commentary.

doi:10.1038/ncb436

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