Showing 1–50 of 97526 results

  1. Research |

    • ...severe cases of FD cite liver failure as a cause of... ...this study, we demonstrate impaired liver function and elevation of various... liver injury markers in Asah1P361R/P361R... ...significant storage pathology within various liver cell types. Lipidomic analyses... ...serum and liver tissue....
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    • ...of Tregs in the neonatal liver under steady-state conditions are... ...of neonatal Tregs in the liver. We found a wave... ...-derived Treg influx into the liver during 1–2 weeks of... ...rapidly resulted in Th1-type liver inflammation and metabolic disorder.... ...in the neonatal liver than in the...
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    • ...in two models of noninfectious liver injury: hemorrhagic shock with... .../− mice had significantly increased liver damage at 6 h after... ...areas of cell death in liver. Caspase-8, a mediator... ...of apoptosis were found in livers of GsdmD−/− mice... ...mild ROS-induced liver injury. However,...
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    • Autotaxin has been associated with liver disease severity and transplant-free... ...Patients reaching an end-point, liver transplantation or death, (discovery... ...increasing autotaxin activity and shorter liver transplant-free survival (discovery... ...risk of liver transplantation or... ...liver...
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    • ...patients also suffering from decompensated liver cirrhosis. In the current... ...in a mouse model of liver fibrosis induced by CCl4 and... ...elevated in hepatocytes of fibrotic livers when compared to normal livers. This upregulation of Dll4... ...-dependent manner. Liver fibroblasts transfected...
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    • Liver failure with hemophagocytic lymphohistiocytosis (... ...lymphohistiocytosis after definite diagnosis of liver failure and to provide clues... ...of HLH in patients with liver failure. Eleven patients diagnosed... with liver failure and HLH were retrospectively... ...of liver failure... ...liver...
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  16. Reviews |

    • ...studies on Alagille syndrome, polycystic liver diseases, fibropolycystic liver diseases (Caroli disease and... ...fibrosis) and cystic fibrosis-related liver disease. In particular, knowledge... ...syndrome, and investigations in polycystic liver diseases have highlighted the role... ...liver...
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    • ...used anti-diabetic agent, and liver glucokinase (GK) has been... ...db/db mice, and increased liver glucose-6-phosphate/glucose-1... ...by analyzing metabolites (serum, liver, and feces) based on... ...enriched BBR distribution in the liver, and liver G-6-P had the... ...with liver BBR levels...liver
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    • ...-hematopoietic or hematopoietic cells during liver injury. This study established... ...of IL-1α in the liver pathology caused by blood-stage... ...on parasitemia control. In the liver, the absence of IL-... ...of IL-1α in the liver of infected mice was inflammatory... ...-1α in liver inflammation...
  20. Reviews |

    • ...the crossroads of the gut, liver, brain and white adipose... ...several diseases affecting the gut–liver axis and to metabolic diseases... ...medical need—such has cholestatic liver diseases and non-alcoholic steatohepatitis...
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    • ...3D model of intestine and liver slices from hamsters that were... ...interior of central veins in liver slices. The three chemically... ...induced signs of cytotoxicity to liver slices. Our results suggest... ...of precision-cut intestinal and liver slices represent a reliable 3D...
  26. Research | | Open

    • ...TR1 cell recruitment to the liver and draining lymph nodes,... ...the pro-inflammatory capacity of liver and liver-proximal myeloid dendritic cells and... ...cells. Thus, autoreactivity against liver-enriched autoantigens in liver autoimmunity is not disease-specific... ...various liver...
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    • ...acetaminophen (APAP)-induced acute liver injury using a PLD2 inhibitor... ...of APAP challenge caused acute liver damage. CAY10594 administration markedly... blocked the acute liver injury in a dose-dependent... ...the pathological progress of acute liver injury, GSH levels are... ...liver...
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  30. Comments and Opinion |

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    • ...organ innervation and regulation. The liver contains sympathetic, parasympathetic, and... ...affect each other. SCI-induced liver inflammation precedes and may exacerbate... ...data through RNA sequencing of liver tissue from rats with chronic... ...associated with known liver pathologies. UCSC...
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    • ...and mutant mice with a liver-specific gene deletion of Liver receptor homolog 1 (Lrh-... ...as well as individuals with liver cancer induced by diethylnitrosamine (... ...measurements in discriminating DEN-induced liver cancer from healthy liver tissue, and are uniquely...
  37. Research |

    • ...II diabetes as adults. The liver is susceptible to fetal undernutrition... ...that influence adult metabolism. Methods Liver samples of male offspring from... ...increased hypoxia signaling in the liver.
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    • ...alcoholic intoxication, and obesity cause liver fibrosis, which progresses to... decompensated liver cirrhosis, a disease for... ...anti-fibrotic therapies for established liver fibrosis, the development of... ...IC-2 sheets) remarkably reduced liver fibrosis induced by chronic CCl4... ...liver...
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    • ...candidate for ameliorating CMD. The liver is the target of BBR... so that liver-site accumulation could be important... ...shell is developed for effective liver deposition of BBR. The... ...the accumulation of BBR in liver is increased by 248.8... ...of-concept for a liver-targeting strategy to...
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