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Amendments and Corrections | 1 February 2001
Erratum A Toll-like receptor recognizes bacterial DNA
- Hiroaki Hemmi
- , Osamu Takeuchi
- , Taro Kawai
- , Tsuneyasu Kaisho
- , Shintaro Sato
- , Hideki Sanjo
- , Makoto Matsumoto
- , Katsuaki Hoshino
- , Hermann Wagner
- , Kiyoshi Takeda
- & Shizuo Akira
Nature 409 , 646–646

Rights & permissionsfor article Erratum A Toll-like receptor recognizes bacterial DNA . Opens in a new window.
Amendments and Corrections | 1 April 2006
Erratum: A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA
- Ken J Ishii
- , Cevayir Coban
- , Hiroki Kato
- , Ken Takahashi
- , Yuichi Torii
- , Fumihiko Takeshita
- , Holger Ludwig
- , Gerd Sutter
- , Koichi Suzuki
- , Hiroaki Hemmi
- , Shintaro Sato
- , Masahiro Yamamoto
- , Satoshi Uematsu
- , Taro Kawai
- , Osamu Takeuchi
- & Shizuo Akira
Nature Immunology 7 , 427–427

Rights & permissionsfor article Erratum: A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA . Opens in a new window.
Research Highlights | 5 January 2009
Inhibition of IRF3-dependent antiviral responses by cellular and viral proteins
Cell Research 19 , 3–4

Rights & permissionsfor article Inhibition of IRF3-dependent antiviral responses by cellular and viral proteins . Opens in a new window.
Research | 9 April 2006
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
- Hiroki Kato
- , Osamu Takeuchi
- , Shintaro Sato
- , Mitsutoshi Yoneyama
- , Masahiro Yamamoto
- , Kosuke Matsui
- , Satoshi Uematsu
- , Andreas Jung
- , Taro Kawai
- , Ken J. Ishii
- , Osamu Yamaguchi
- , Kinya Otsu
- , Tohru Tsujimura
- , Chang-Sung Koh
- , Caetano Reis e Sousa
- , Yoshiharu Matsuura
- , Takashi Fujita
- & Shizuo Akira
Nature 441 , 101–105

Rights & permissionsfor article Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses . Opens in a new window.
Reviews | 19 January 2006
Innate immune recognition of viral infection
- Taro Kawai
- & Shizuo Akira
Nature Immunology 7 , 131–137

Rights & permissionsfor article Innate immune recognition of viral infection . Opens in a new window.
Research | 7 February 2008
TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines
- Ken J. Ishii
- , Tatsukata Kawagoe
- , Shohei Koyama
- , Kosuke Matsui
- , Himanshu Kumar
- , Taro Kawai
- , Satoshi Uematsu
- , Osamu Takeuchi
- , Fumihiko Takeshita
- , Cevayir Coban
- & Shizuo Akira
Nature 451 , 725–729

Rights & permissionsfor article TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines . Opens in a new window.
Research | 7 December 2000
A Toll-like receptor recognizes bacterial DNA
- Hiroaki Hemmi
- , Osamu Takeuchi
- , Taro Kawai
- , Tsuneyasu Kaisho
- , Shintaro Sato
- , Hideki Sanjo
- , Makoto Matsumoto
- , Katsuaki Hoshino
- , Hermann Wagner
- , Kiyoshi Takeda
- & Shizuo Akira
Nature 408 , 740–745

Rights & permissionsfor article A Toll-like receptor recognizes bacterial DNA . Opens in a new window.
Research | 5 October 2008
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
- Tatsuya Saitoh
- , Naonobu Fujita
- , Myoung Ho Jang
- , Satoshi Uematsu
- , Bo-Gie Yang
- , Takashi Satoh
- , Hiroko Omori
- , Takeshi Noda
- , Naoki Yamamoto
- , Masaaki Komatsu
- , Keiji Tanaka
- , Taro Kawai
- , Tohru Tsujimura
- , Osamu Takeuchi
- , Tamotsu Yoshimori
- & Shizuo Akira
Nature 456 , 264–268

Rights & permissionsfor article Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production . Opens in a new window.
Research | 9 July 2006
Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c⁺ lamina propria cells
- Satoshi Uematsu
- , Myoung Ho Jang
- , Nicolas Chevrier
- , Zijin Guo
- , Yutaro Kumagai
- , Masahiro Yamamoto
- , Hiroki Kato
- , Nagako Sougawa
- , Hidenori Matsui
- , Hirotaka Kuwata
- , Hiroaki Hemmi
- , Cevayir Coban
- , Taro Kawai
- , Ken J Ishii
- , Osamu Takeuchi
- , Masayuki Miyasaka
- , Kiyoshi Takeda
- & Shizuo Akira
Nature Immunology 7 , 868–874

Rights & permissionsfor article Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c<sup>+</sup> lamina propria cells . Opens in a new window.
15 June 1999
Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity
- Taro Kawai
- , Fumiko Nomura
- , Katsuaki Hoshino
- , Neal G Copeland
- , Debra J Gilbert
- , Nancy A Jenkins
- & Shizuo Akira
Oncogene 18 , 3471–3480

Rights & permissionsfor article Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity . Opens in a new window.
Research | 9 March 2015 | Open
TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus
- Taito Matsuda
- , Naoya Murao
- , Yuki Katano
- , Berry Juliandi
- , Jun Kohyama
- , Shizuo Akira
- , Taro Kawai
- & Kinichi Nakashima
Nature Communications 6 , 1–10

Rights & permissionsfor article TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus . Opens in a new window.
Research | 31 July 2013
Completion of the entire hepatitis C virus life cycle in genetically humanized mice
- Marcus Dorner
- , Joshua A. Horwitz
- , Bridget M. Donovan
- , Rachael N. Labitt
- , William C. Budell
- , Tamar Friling
- , Alexander Vogt
- , Maria Teresa Catanese
- , Takashi Satoh
- , Taro Kawai
- , Shizuo Akira
- , Mansun Law
- , Charles M. Rice
- & Alexander Ploss
Nature 501 , 237–241

Rights & permissionsfor article Completion of the entire hepatitis C virus life cycle in genetically humanized mice . Opens in a new window.
Research | 10 April 2014
Nucleic acid sensing by T cells initiates Th2 cell differentiation
- Takayuki Imanishi
- , Chitose Ishihara
- , Mohamed El Sherif Gadelhaq Badr
- , Akiko Hashimoto-Tane
- , Yayoi Kimura
- , Taro Kawai
- , Osamu Takeuchi
- , Ken J. Ishii
- , Shun'ichiro Taniguchi
- , Tetsuo Noda
- , Hisashi Hirano
- , Frank Brombacher
- , Glen N. Barber
- , Shizuo Akira
- & Takashi Saito
Nature Communications 5 , 1–12

Rights & permissionsfor article Nucleic acid sensing by T cells initiates Th2 cell differentiation . Opens in a new window.
Research | 18 March 2014 | Open
Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome
- Naoki Takemura
- , Takumi Kawasaki
- , Jun Kunisawa
- , Shintaro Sato
- , Aayam Lamichhane
- , Kouji Kobiyama
- , Taiki Aoshi
- , Junichi Ito
- , Kenji Mizuguchi
- , Thangaraj Karuppuchamy
- , Kouta Matsunaga
- , Shoichiro Miyatake
- , Nobuko Mori
- , Tohru Tsujimura
- , Takashi Satoh
- , Yutaro Kumagai
- , Taro Kawai
- , Daron M. Standley
- , Ken J. Ishii
- , Hiroshi Kiyono
- , Shizuo Akira
- & Satoshi Uematsu
Nature Communications 5 , 1–15

Rights & permissionsfor article Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome . Opens in a new window.
Research | 13 November 2005
A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA
- Ken J Ishii
- , Cevayir Coban
- , Hiroki Kato
- , Ken Takahashi
- , Yuichi Torii
- , Fumihiko Takeshita
- , Holger Ludwig
- , Gerd Sutter
- , Koichi Suzuki
- , Hiroaki Hemmi
- , Shintaro Sato
- , Masahiro Yamamoto
- , Satoshi Uematsu
- , Taro Kawai
- , Osamu Takeuchi
- & Shizuo Akira
Nature Immunology 7 , 40–48

Rights & permissionsfor article A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA . Opens in a new window.
Research | 25 September 2005
Essential function for the kinase TAK1 in innate and adaptive immune responses
- Shintaro Sato
- , Hideki Sanjo
- , Kiyoshi Takeda
- , Jun Ninomiya-Tsuji
- , Masahiro Yamamoto
- , Taro Kawai
- , Kunihiro Matsumoto
- , Osamu Takeuchi
- & Shizuo Akira
Nature Immunology 6 , 1087–1095

Rights & permissionsfor article Essential function for the kinase TAK1 in innate and adaptive immune responses . Opens in a new window.
Research | 23 July 2006
Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling
- Masahiro Yamamoto
- , Toru Okamoto
- , Kiyoshi Takeda
- , Shintaro Sato
- , Hideki Sanjo
- , Satoshi Uematsu
- , Tatsuya Saitoh
- , Naoki Yamamoto
- , Hiroaki Sakurai
- , Ken J Ishii
- , Shoji Yamaoka
- , Taro Kawai
- , Yoshiharu Matsuura
- , Osamu Takeuchi
- & Shizuo Akira
Nature Immunology 7 , 962–970

Rights & permissionsfor article Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling . Opens in a new window.
Research | 7 September 2004
Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
- Taro Kawai
- , Shintaro Sato
- , Ken J Ishii
- , Cevayir Coban
- , Hiroaki Hemmi
- , Masahiro Yamamoto
- , Kenta Terai
- , Michiyuki Matsuda
- , Jun-ichiro Inoue
- , Satoshi Uematsu
- , Osamu Takeuchi
- & Shizuo Akira
Nature Immunology 5 , 1061–1068

Rights & permissionsfor article Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6 . Opens in a new window.
Research | 27 April 2008
Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2
- Tatsukata Kawagoe
- , Shintaro Sato
- , Kazufumi Matsushita
- , Hiroki Kato
- , Kosuke Matsui
- , Yutaro Kumagai
- , Tatsuya Saitoh
- , Taro Kawai
- , Osamu Takeuchi
- & Shizuo Akira
Nature Immunology 9 , 684–691

Rights & permissionsfor article Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2 . Opens in a new window.
Reviews | 20 April 2010
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors
- Taro Kawai
- & Shizuo Akira
Nature Immunology 11 , 373–384

Rights & permissionsfor article The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors . Opens in a new window.
Research | 28 August 2005
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
- Taro Kawai
- , Ken Takahashi
- , Shintaro Sato
- , Cevayir Coban
- , Himanshu Kumar
- , Hiroki Kato
- , Ken J Ishii
- , Osamu Takeuchi
- & Shizuo Akira
Nature Immunology 6 , 981–988

Rights & permissionsfor article IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction . Opens in a new window.

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Erratum A Toll-like receptor recognizes bacterial DNA

Erratum: A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

Inhibition of IRF3-dependent antiviral responses by cellular and viral proteins

Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

Innate immune recognition of viral infection

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

A Toll-like receptor recognizes bacterial DNA

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c⁺ lamina propria cells

Death-associated protein kinase 2 is a new calcium/calmodulin-dependent protein kinase that signals apoptosis through its catalytic activity

TLR9 signalling in microglia attenuates seizure-induced aberrant neurogenesis in the adult hippocampus

Completion of the entire hepatitis C virus life cycle in genetically humanized mice

Nucleic acid sensing by T cells initiates Th2 cell differentiation

Blockade of TLR3 protects mice from lethal radiation-induced gastrointestinal syndrome

A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA

Essential function for the kinase TAK1 in innate and adaptive immune responses

Key function for the Ubc13 E2 ubiquitin-conjugating enzyme in immune receptor signaling

Interferon-α induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6

Sequential control of Toll-like receptor–dependent responses by IRAK1 and IRAK2

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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