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Research | 1 November 2019 | Open
Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels
- Zsolt Bagi
- , Yvonne Couch
- , Zuzana Broskova
- , Francisco Perez-Balderas
- , Tianrong Yeo
- , Simon Davis
- , Roman Fischer
- , Nicola R. Sibson
- , Benjamin G. Davis
- & Daniel C. Anthony
Scientific Reports 9 , 1–10

Rights & permissionsfor article Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels . Opens in a new window.
Research | 17 July 2019 | Open
SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication
- Swagata Halder
- , Ignacio Torrecilla
- , Martin D. Burkhalter
- , Marta Popović
- , John Fielden
- , Bruno Vaz
- , Judith Oehler
- , Domenic Pilger
- , Davor Lessel
- , Katherine Wiseman
- , Abhay Narayan Singh
- , Iolanda Vendrell
- , Roman Fischer
- , Melanie Philipp
- & Kristijan Ramadan
Nature Communications 10 , 1–18

Rights & permissionsfor article SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication . Opens in a new window.
Amendments and Corrections | 27 June 2018
Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
- Suzana Markolovic
- , Qinqin Zhuang
- , Sarah E. Wilkins
- , Charlotte D. Eaton
- , Martine I. Abboud
- , Maximiliano J. Katz
- , Helen E. McNeil
- , Robert K. Leśniak
- , Charlotte Hall
- , Weston B. Struwe
- , Rebecca Konietzny
- , Simon Davis
- , Ming Yang
- , Wei Ge
- , Justin L. P. Benesch
- , Benedikt M. Kessler
- , Peter J. Ratcliffe
- , Matthew E. Cockman
- , Roman Fischer
- , Pablo Wappner
- , Rasheduzzaman Chowdhury
- , Mathew L. Coleman
- & Christopher J. Schofield
Nature Chemical Biology 14 , 988–988

Rights & permissionsfor article Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3<i>S</i>)-lysyl hydroxylation of TRAFAC GTPases . Opens in a new window.
Research | 6 June 2019 | Open
Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells
Nature Communications 10 , 1–17

Rights & permissionsfor article Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells . Opens in a new window.
Research | 6 June 2019
Palaeoproteomics resolves sloth relationships
- Samantha Presslee
- , Graham J. Slater
- , François Pujos
- , Analía M. Forasiepi
- , Roman Fischer
- , Kelly Molloy
- , Meaghan Mackie
- , Jesper V. Olsen
- , Alejandro Kramarz
- , Matías Taglioretti
- , Fernando Scaglia
- , Maximiliano Lezcano
- , José Luis Lanata
- , John Southon
- , Robert Feranec
- , Jonathan Bloch
- , Adam Hajduk
- , Fabiana M. Martin
- , Rodolfo Salas Gismondi
- , Marcelo Reguero
- , Christian de Muizon
- , Alex Greenwood
- , Brian T. Chait
- , Kirsty Penkman
- , Matthew Collins
- & Ross D. E. MacPhee
Nature Ecology & Evolution 3 , 1121–1130

Rights & permissionsfor article Palaeoproteomics resolves sloth relationships . Opens in a new window.
Research | 1 May 2019
A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau
- Fahu Chen
- , Frido Welker
- , Chuan-Chou Shen
- , Shara E. Bailey
- , Inga Bergmann
- , Simon Davis
- , Huan Xia
- , Hui Wang
- , Roman Fischer
- , Sarah E. Freidline
- , Tsai-Luen Yu
- , Matthew M. Skinner
- , Stefanie Stelzer
- , Guangrong Dong
- , Qiaomei Fu
- , Guanghui Dong
- , Jian Wang
- , Dongju Zhang
- & Jean-Jacques Hublin
Nature 569 , 409–412

Rights & permissionsfor article A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau . Opens in a new window.
Research | 26 July 2017 | Open
New criteria for the molecular identification of cereal grains associated with archaeological artefacts
Scientific Reports 7 , 1–7

Rights & permissionsfor article New criteria for the molecular identification of cereal grains associated with archaeological artefacts . Opens in a new window.
Research | 27 February 2019
Colonic epithelial cell diversity in health and inflammatory bowel disease
- Kaushal Parikh
- , Agne Antanaviciute
- , David Fawkner-Corbett
- , Marta Jagielowicz
- , Anna Aulicino
- , Christoffer Lagerholm
- , Simon Davis
- , James Kinchen
- , Hannah H. Chen
- , Nasullah Khalid Alham
- , Neil Ashley
- , Errin Johnson
- , Philip Hublitz
- , Leyuan Bao
- , Joanna Lukomska
- , Rajinder Singh Andev
- , Elisabet Björklund
- , Benedikt M. Kessler
- , Roman Fischer
- , Robert Goldin
- , Hashem Koohy
- & Alison Simmons
Nature 567 , 49–55

Rights & permissionsfor article Colonic epithelial cell diversity in health and inflammatory bowel disease . Opens in a new window.
Research | 8 November 2018 | Open
Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion
Nature Communications 9 , 1–10

Rights & permissionsfor article Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion . Opens in a new window.
Research | 18 September 2018 | Open
A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes
Nature Communications 9 , 1–14

Rights & permissionsfor article A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes . Opens in a new window.
Research | 25 September 2018 | Open
Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation
- Jade Bailey
- , Simon Davis
- , Andrew Shaw
- , Marina Diotallevi
- , Roman Fischer
- , Matthew A. Benson
- , Hanneng Zhu
- , James Brown
- , Shoumo Bhattacharya
- , Benedikt M. Kessler
- , Keith M. Channon
- & Mark J. Crabtree
Scientific Reports 8 , 1–13

Rights & permissionsfor article Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation . Opens in a new window.
Research | 3 October 2018 | Open
Ancient proteins from ceramic vessels at Çatalhöyük West reveal the hidden cuisine of early farmers
- Jessica Hendy
- , Andre C. Colonese
- , Ingmar Franz
- , Ricardo Fernandes
- , Roman Fischer
- , David Orton
- , Alexandre Lucquin
- , Luke Spindler
- , Jana Anvari
- , Elizabeth Stroud
- , Peter F. Biehl
- , Camilla Speller
- , Nicole Boivin
- , Meaghan Mackie
- , Rosa R. Jersie-Christensen
- , Jesper V. Olsen
- , Matthew J. Collins
- , Oliver E. Craig
- & Eva Rosenstock
Nature Communications 9 , 1–10

Rights & permissionsfor article Ancient proteins from ceramic vessels at Çatalhöyük West reveal the hidden cuisine of early farmers . Opens in a new window.
Research | 25 July 2018
53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ
Nature 560 , 122–127

Rights & permissionsfor article 53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ . Opens in a new window.
Research | 11 September 2018 | Open
Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis
- Sarah K. Williams
- , Richard Fairless
- , Olaf Maier
- , Patricia C. Liermann
- , Kira Pichi
- , Roman Fischer
- , Ulrich L. M. Eisel
- , Roland Kontermann
- , Andreas Herrmann
- , Babette Weksler
- , Nacho Romero
- , Pierre-Olivier Couraud
- , Klaus Pfizenmaier
- & Ricarda Diem
Scientific Reports 8 , 1–14

Rights & permissionsfor article Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis . Opens in a new window.
Research | 18 June 2018
The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases
- Suzana Markolovic
- , Qinqin Zhuang
- , Sarah E. Wilkins
- , Charlotte D. Eaton
- , Martine I. Abboud
- , Maximiliano J. Katz
- , Helen E. McNeil
- , Robert K. Leśniak
- , Charlotte Hall
- , Weston B. Struwe
- , Rebecca Konietzny
- , Simon Davis
- , Ming Yang
- , Wei Ge
- , Justin L. P. Benesch
- , Benedikt M. Kessler
- , Peter J. Ratcliffe
- , Matthew E. Cockman
- , Roman Fischer
- , Pablo Wappner
- , Rasheduzzaman Chowdhury
- , Mathew L. Coleman
- & Christopher J. Schofield
Nature Chemical Biology 14 , 688–695

Rights & permissionsfor article The Jumonji-C oxygenase JMJD7 catalyzes (3<i>S</i>)-lysyl hydroxylation of TRAFAC GTPases . Opens in a new window.
Research | 4 June 2018 | Open
Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion
Scientific Reports 8 , 1–12

Rights & permissionsfor article Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion . Opens in a new window.
Research | 11 July 2018 | Open
A TFEB nuclear export signal integrates amino acid supply and glucose availability
Nature Communications 9 , 1–15

Rights & permissionsfor article A TFEB nuclear export signal integrates amino acid supply and glucose availability . Opens in a new window.
Research | 28 March 2018
Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
- Evanna L. Mills
- , Dylan G. Ryan
- , Hiran A. Prag
- , Dina Dikovskaya
- , Deepthi Menon
- , Zbigniew Zaslona
- , Mark P. Jedrychowski
- , Ana S. H. Costa
- , Maureen Higgins
- , Emily Hams
- , John Szpyt
- , Marah C. Runtsch
- , Martin S. King
- , Joanna F. McGouran
- , Roman Fischer
- , Benedikt M. Kessler
- , Anne F. McGettrick
- , Mark M. Hughes
- , Richard G. Carroll
- , Lee M. Booty
- , Elena V. Knatko
- , Paul J. Meakin
- , Michael L. J. Ashford
- , Louise K. Modis
- , Gino Brunori
- , Daniel C. Sévin
- , Padraic G. Fallon
- , Stuart T. Caldwell
- , Edmund R. S. Kunji
- , Edward T. Chouchani
- , Christian Frezza
- , Albena T. Dinkova-Kostova
- , Richard C. Hartley
- , Michael P. Murphy
- & Luke A. O’Neill
Nature 556 , 113–117

Rights & permissionsfor article Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 . Opens in a new window.
Research | 26 July 2017 | Open
Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2
Scientific Reports 7 , 1–13

Rights & permissionsfor article Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2 . Opens in a new window.
Research | 15 April 2016 | Open
Integrative Phosphoproteomics Links IL-23R Signaling with Metabolic Adaptation in Lymphocytes
Scientific Reports 6 , 1–12

Rights & permissionsfor article Integrative Phosphoproteomics Links IL-23R Signaling with Metabolic Adaptation in Lymphocytes . Opens in a new window.
Research | 23 May 2016 | Open
Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses
Scientific Reports 6 , 1–12

Rights & permissionsfor article Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses . Opens in a new window.
Research | 18 March 2015
Ancient proteins resolve the evolutionary history of Darwin’s South American ungulates
- Frido Welker
- , Matthew J. Collins
- , Jessica A. Thomas
- , Marc Wadsley
- , Selina Brace
- , Enrico Cappellini
- , Samuel T. Turvey
- , Marcelo Reguero
- , Javier N. Gelfo
- , Alejandro Kramarz
- , Joachim Burger
- , Jane Thomas-Oates
- , David A. Ashford
- , Peter D. Ashton
- , Keri Rowsell
- , Duncan M. Porter
- , Benedikt Kessler
- , Roman Fischer
- , Carsten Baessmann
- , Stephanie Kaspar
- , Jesper V. Olsen
- , Patrick Kiley
- , James A. Elliott
- , Christian D. Kelstrup
- , Victoria Mullin
- , Michael Hofreiter
- , Eske Willerslev
- , Jean-Jacques Hublin
- , Ludovic Orlando
- , Ian Barnes
- & Ross D. E. MacPhee
Nature 522 , 81–84

Rights & permissionsfor article Ancient proteins resolve the evolutionary history of Darwin’s South American ungulates . Opens in a new window.

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Extracellular vesicle integrins act as a nexus for platelet adhesion in cerebral microvessels

SPRTN protease and checkpoint kinase 1 cross-activation loop safeguards DNA replication

Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

Diabetes causes marked inhibition of mitochondrial metabolism in pancreatic β-cells

Palaeoproteomics resolves sloth relationships

A late Middle Pleistocene Denisovan mandible from the Tibetan Plateau

New criteria for the molecular identification of cereal grains associated with archaeological artefacts

Colonic epithelial cell diversity in health and inflammatory bowel disease

Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes

Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation

Ancient proteins from ceramic vessels at Çatalhöyük West reveal the hidden cuisine of early farmers

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ

Anti-TNFR1 targeting in humanized mice ameliorates disease in a model of multiple sclerosis

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases

Proteo-metabolomics reveals compensation between ischemic and non-injured contralateral kidneys after reperfusion

A TFEB nuclear export signal integrates amino acid supply and glucose availability

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

Novel strategies to mimic transmembrane tumor necrosis factor-dependent activation of tumor necrosis factor receptor 2

Integrative Phosphoproteomics Links IL-23R Signaling with Metabolic Adaptation in Lymphocytes

Abrogation of collagen-induced arthritis by a peptidyl arginine deiminase inhibitor is associated with modulation of T cell-mediated immune responses

Ancient proteins resolve the evolutionary history of Darwin’s South American ungulates

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