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Research | 6 December 2019
A TGF-β-MTA1-SOX4-EZH2 signaling axis drives epithelial–mesenchymal transition in tumor metastasis
- Lina Li
- , Jian Liu
- , Hongsheng Xue
- , Chunxiao Li
- , Qun Liu
- , Yantong Zhou
- , Ting Wang
- , Haijuan Wang
- , Haili Qian
- & Tao Wen
Oncogene , 1–15

Rights & permissionsfor article A TGF-β-MTA1-SOX4-EZH2 signaling axis drives epithelial–mesenchymal transition in tumor metastasis . Opens in a new window.
Research | 20 September 2019 | Open
Inactivation of NF-κB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction
- Wen-Song Zhang
- , An Pan
- , Xu Zhang
- , Ang Ying
- , Gaoxiang Ma
- , Bao-Lin Liu
- , Lian-Wen Qi
- , Qun Liu
- & Ping Li
Nature Communications 10 , 1–10

Rights & permissionsfor article Inactivation of NF-κB2 (p52) restrains hepatic glucagon response via preserving PDE4B induction . Opens in a new window.
Amendments and Corrections | 1 February 2007
Erratum: Corrigendum: Structural basis for modulation of Kv4 K⁺ channels by auxiliary KChIP subunits
- Huayi Wang
- , Yan Yan
- , Qun Liu
- , Yanhua Huang
- , Yue Shen
- , Linjie Chen
- , Yi Chen
- , Qiuyue Yang
- , Quan Hao
- , KeWei Wang
- & Jijie Chai
Nature Neuroscience 10 , 263–263

Rights & permissionsfor article Erratum: Corrigendum: Structural basis for modulation of Kv4 K<sup>+</sup> channels by auxiliary KChIP subunits . Opens in a new window.
Research | 3 December 2018 | Open
Nitrogen additions stimulate litter humification in a subtropical forest, southwestern China
- Qun Liu
- , Liyan Zhuang
- , Xiangyin Ni
- , Chengming You
- , Wanqin Yang
- , Fuzhong Wu
- , Bo Tan
- , Kai Yue
- , Yang Liu
- , Li Zhang
- & Zhenfeng Xu
Scientific Reports 8 , 1–8

Rights & permissionsfor article Nitrogen additions stimulate litter humification in a subtropical forest, southwestern China . Opens in a new window.
Correspondence | 16 March 2018
The uncertainty of population relationship and divergence time inferred by the multiple sequentially Markovian coalescent model
- Xing-Yan Yang
- , Shan-Shan Dai
- , He-Qun Liu
- , Min-Sheng Peng
- & Ya-Ping Zhang
Journal of Human Genetics 63 , 775–777

Rights & permissionsfor article The uncertainty of population relationship and divergence time inferred by the multiple sequentially Markovian coalescent model . Opens in a new window.
Research | 16 August 2017 | Open
Spatial Regression and Prediction of Water Quality in a Watershed with Complex Pollution Sources
- Xiaoying Yang
- , Qun Liu
- , Xingzhang Luo
- & Zheng Zheng
Scientific Reports 7 , 1–11

Rights & permissionsfor article Spatial Regression and Prediction of Water Quality in a Watershed with Complex Pollution Sources . Opens in a new window.
Research | 20 September 2017 | Open
Survival and prognostic factors in hypertrophic cardiomyopathy: a meta-analysis
- Qun Liu
- , Diandian Li
- , Alan E. Berger
- , Roger A. Johns
- & Li Gao
Scientific Reports 7 , 1–10

Rights & permissionsfor article Survival and prognostic factors in hypertrophic cardiomyopathy: a meta-analysis . Opens in a new window.
Research | 29 March 2019 | Open
Transcriptomic analysis of the prothoracic gland from two lepidopteran insects, domesticated silkmoth Bombyx mori and wild silkmoth Antheraea pernyi
- Hai-Xu Bian
- , Dong-Bin Chen
- , Xi-Xi Zheng
- , Hong-Fang Ma
- , Yu-Ping Li
- , Qun Li
- , Run-Xi Xia
- , Huan Wang
- , Yi-Ren Jiang
- , Yan-Qun Liu
- & Li Qin
Scientific Reports 9 , 1–12

Rights & permissionsfor article Transcriptomic analysis of the prothoracic gland from two lepidopteran insects, domesticated silkmoth <i>Bombyx mori</i> and wild silkmoth <i>Antheraea pernyi</i> . Opens in a new window.
Research | 19 December 2016 | Open
Distinct urine metabolome after Asian ginseng and American ginseng intervention based on GC-MS metabolomics approach
- Liu Yang
- , Qing-Tao Yu
- , Ya-Zhong Ge
- , Wen-Song Zhang
- , Yong Fan
- , Chung-Wah Ma
- , Qun Liu
- & Lian-Wen Qi
Scientific Reports 6 , 1–11

Rights & permissionsfor article Distinct urine metabolome after Asian ginseng and American ginseng intervention based on GC-MS metabolomics approach . Opens in a new window.
Research | 13 December 2016 | Open
Structural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion
- Menglong Hu
- , Hongmin Zhang
- , Qun Liu
- & Quan Hao
Scientific Reports 6 , 1–8

Rights & permissionsfor article Structural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion . Opens in a new window.
Research | 29 July 2016 | Open
Mitofusin 2 regulates the oocytes development and quality by modulating meiosis and mitochondrial function
- Qun Liu
- , Lina Kang
- , Lingjuan Wang
- , Ling Zhang
- & Wenpei Xiang
Scientific Reports 6 , 1–8

Rights & permissionsfor article Mitofusin 2 regulates the oocytes development and quality by modulating meiosis and mitochondrial function . Opens in a new window.
Research | 1 June 2016 | Open
4-Trifluoromethyl-p-quinols as dielectrophiles: three-component, double nucleophilic addition/aromatization reactions
- Jinhuan Dong
- , Lou Shi
- , Ling Pan
- , Xianxiu Xu
- & Qun Liu
Scientific Reports 6 , 1–11

Rights & permissionsfor article 4-Trifluoromethyl-<i>p</i>-quinols as dielectrophiles: three-component, double nucleophilic addition/aromatization reactions . Opens in a new window.
Research | 26 February 2015 | Open
Rapid preparation of rare ginsenosides by acid transformation and their structure-activity relationships against cancer cells
- Kai Quan
- , Qun Liu
- , Jin-Yi Wan
- , Yi-Jing Zhao
- , Ru-Zhou Guo
- , Raphael N. Alolga
- , Ping Li
- & Lian-Wen Qi
Scientific Reports 5 , 1–7

Rights & permissionsfor article Rapid preparation of rare ginsenosides by acid transformation and their structure-activity relationships against cancer cells . Opens in a new window.
Research | 5 June 2015 | Open
Plasmon coupling in vertical split-ring resonator metamolecules
- Pin Chieh Wu
- , Wei-Lun Hsu
- , Wei Ting Chen
- , Yao-Wei Huang
- , Chun Yen Liao
- , Ai Qun Liu
- , Nikolay I. Zheludev
- , Greg Sun
- & Din Ping Tsai
Scientific Reports 5 , 1–5

Rights & permissionsfor article Plasmon coupling in vertical split-ring resonator metamolecules . Opens in a new window.
Research | 1 October 2014
Isoquinoline alkaloids from Zanthoxylum simulans and their biological evaluation
- Sheng-Hui Yang
- , Yan-Qun Liu
- , Jun-Feng Wang
- , Yue-Hu Wang
- , Wei-Wei Pan
- , Wen-Bing Sheng
- , Rui Cai
- & Xiao-Jiang Zhou
The Journal of Antibiotics 68 , 289–292

Rights & permissionsfor article Isoquinoline alkaloids from <i>Zanthoxylum simulans</i> and their biological evaluation . Opens in a new window.
Research | 21 October 2012
Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter
- Romina Mancusso
- , G. Glenn Gregorio
- , Qun Liu
- & Da-Neng Wang
Nature 491 , 622–626

Rights & permissionsfor article Structure and mechanism of a bacterial sodium-dependent dicarboxylate transporter . Opens in a new window.
Research | 4 June 2014
PA-1, a novel synthesized pyrrolizidine alkaloid, inhibits the growth of Escherichia coli and Staphylococcus aureus by damaging the cell membrane
- Na Li
- , Sheng-nan Tan
- , Jian Cui
- , Na Guo
- , Wei Wang
- , Yuan-gang Zu
- , Shuang Jin
- , Xian-xiu Xu
- , Qun Liu
- & Yu-jie Fu
The Journal of Antibiotics 67 , 689–696

Rights & permissionsfor article PA-1, a novel synthesized pyrrolizidine alkaloid, inhibits the growth of <i>Escherichia coli</i> and <i>Staphylococcus aureus</i> by damaging the cell membrane . Opens in a new window.
Research | 10 December 2018 | Open
Fall webworm genomes yield insights into rapid adaptation of invasive species
- Ningning Wu
- , Sufang Zhang
- , Xiaowei Li
- , Yanghui Cao
- , Xiaojing Liu
- , Qinghua Wang
- , Qun Liu
- , Huihui Liu
- , Xiao Hu
- , Xuguo J. Zhou
- , Anthony A. James
- , Zhen Zhang
- , Yongping Huang
- & Shuai Zhan
Nature Ecology & Evolution 3 , 105–115

Rights & permissionsfor article Fall webworm genomes yield insights into rapid adaptation of invasive species . Opens in a new window.
Research | 6 October 2005
Structure of the CED-4–CED-9 complex provides insights into programmed cell death in Caenorhabditis elegans
- Nieng Yan
- , Jijie Chai
- , Eui Seung Lee
- , Lichuan Gu
- , Qun Liu
- , Jiaqing He
- , Jia-Wei Wu
- , David Kokel
- , Huilin Li
- , Quan Hao
- , Ding Xue
- & Yigong Shi
Nature 437 , 831–837

Rights & permissionsfor article Structure of the CED-4–CED-9 complex provides insights into programmed cell death in <i>Caenorhabditis elegans</i> . Opens in a new window.
Research | 12 August 2007
The structural basis for activation of plant immunity by bacterial effector protein AvrPto
- Weiman Xing
- , Yan Zou
- , Qun Liu
- , Jianing Liu
- , Xi Luo
- , Qingqiu Huang
- , She Chen
- , Lihuang Zhu
- , Ruchang Bi
- , Quan Hao
- , Jia-Wei Wu
- , Jian-Min Zhou
- & Jijie Chai
Nature 449 , 243–247

Rights & permissionsfor article The structural basis for activation of plant immunity by bacterial effector protein AvrPto . Opens in a new window.
Research | 20 June 2018 | Open
Expression patterns of programmed death ligand 1 correlate with different microenvironments and patient prognosis in hepatocellular carcinoma
- Chao-Qun Liu
- , Jing Xu
- , Zhong-Guo Zhou
- , Li-Lian Jin
- , Xing-Juan Yu
- , Gang Xiao
- , Jie Lin
- , Shi-Mei Zhuang
- , Yao-Jun Zhang
- & Limin Zheng
British Journal of Cancer 119 , 80–88

Rights & permissionsfor article Expression patterns of programmed death ligand 1 correlate with different microenvironments and patient prognosis in hepatocellular carcinoma . Opens in a new window.
Research | 4 June 2018 | Open
Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling
- Yi-Tong Lu
- , Lan-Zhu Li
- , Yi-Lin Yang
- , Xiaojian Yin
- , Qun Liu
- , Lei Zhang
- , Kang Liu
- , Baolin Liu
- , Jia Li
- & Lian-Wen Qi
Cell Death & Disease 9 , 1–14

Rights & permissionsfor article Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling . Opens in a new window.
Research | 23 March 2018 | Open
Cut Based Method for Comparing Complex Networks
- Qun Liu
- , Zhishan Dong
- & En Wang
Scientific Reports 8 , 1–11

Rights & permissionsfor article Cut Based Method for Comparing Complex Networks . Opens in a new window.
Research | 17 May 2018
Suppression of MIF-induced neuronal apoptosis may underlie the therapeutic effects of effective components of Fufang Danshen in the treatment of Alzheimer's disease
- Cheng-jie Liang
- , Jia-huang Li
- , Zhen Zhang
- , Ju-yan Zhang
- , Shu-qun Liu
- & Jie Yang
Acta Pharmacologica Sinica 39 , 1421–1438

Rights & permissionsfor article Suppression of MIF-induced neuronal apoptosis may underlie the therapeutic effects of effective components of Fufang Danshen in the treatment of Alzheimer's disease . Opens in a new window.
Research | 29 November 2017
Mitochondrial genomes uncover the maternal history of the Pamir populations
- Min-Sheng Peng
- , Weifang Xu
- , Jiao-Jiao Song
- , Xing Chen
- , Xierzhatijiang Sulaiman
- , Liuhong Cai
- , He-Qun Liu
- , Shi-Fang Wu
- , Yun Gao
- , Najmudinov Tojiddin Abdulloevich
- , Manilova Elena Afanasevna
- , Khudoidodov Behruz Ibrohimovich
- , Xi Chen
- , Wei-Kang Yang
- , Miao Wu
- , Gui-Mei Li
- , Xing-Yan Yang
- , Allah Rakha
- , Yong-Gang Yao
- , Halmurat Upur
- & Ya-Ping Zhang
European Journal of Human Genetics 26 , 124–136

Rights & permissionsfor article Mitochondrial genomes uncover the maternal history of the Pamir populations . Opens in a new window.
Research | 23 March 2017 | Open
Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus
- Xiao-Juan Li
- , Qing-Yu Ma
- , You-Ming Jiang
- , Xiao-Hui Bai
- , Zhi-Yi Yan
- , Qun Liu
- , Qiu-Xia Pan
- , Yue-Yun Liu
- & Jia-Xu Chen
Scientific Reports 7 , 1–13

Rights & permissionsfor article Xiaoyaosan exerts anxiolytic-like effects by down-regulating the TNF-α/JAK2-STAT3 pathway in the rat hippocampus . Opens in a new window.
Research | 8 March 2017 | Open
A network-based method for mechanistic investigation of Shexiang Baoxin Pill’s treatment of cardiovascular diseases
- Hai-Yang Fang
- , Hua-Wu Zeng
- , Li-Mei Lin
- , Xing Chen
- , Xiao-Na Shen
- , Peng Fu
- , Chao Lv
- , Qun Liu
- , Run-Hui Liu
- , Wei-Dong Zhang
- & Jing Zhao
Scientific Reports 7 , 1–11

Rights & permissionsfor article A network-based method for mechanistic investigation of Shexiang Baoxin Pill’s treatment of cardiovascular diseases . Opens in a new window.
Research | 24 May 2017 | Open
Characterization of the Adult Head Transcriptome and Identification of Migration and Olfaction Genes in the Oriental Armyworm Mythimna separate
- Hai-Xu Bian
- , Hong-Fang Ma
- , Xi-Xi Zheng
- , Ming-Hui Peng
- , Yu-Ping Li
- , Jun-Fang Su
- , Huan Wang
- , Qun Li
- , Run-Xi Xia
- , Yan-Qun Liu
- & Xing-Fu Jiang
Scientific Reports 7 , 1–11

Rights & permissionsfor article Characterization of the Adult Head Transcriptome and Identification of Migration and Olfaction Genes in the Oriental Armyworm <i>Mythimna separate</i> . Opens in a new window.
Research | 23 February 2017 | Open
Ginsenoside Rg5 increases cardiomyocyte resistance to ischemic injury through regulation of mitochondrial hexokinase-II and dynamin-related protein 1
- Yi-Lin Yang
- , Jia Li
- , Kang Liu
- , Lei Zhang
- , Qun Liu
- , Baolin Liu
- & Lian-Wen Qi
Cell Death & Disease 8 , e2625–e2625

Rights & permissionsfor article Ginsenoside Rg5 increases cardiomyocyte resistance to ischemic injury through regulation of mitochondrial hexokinase-II and dynamin-related protein 1 . Opens in a new window.
Research | 1 April 2016
Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication
- Ming-Shan Wang
- , Rong-wei Zhang
- , Ling-Yan Su
- , Yan Li
- , Min-Sheng Peng
- , He-Qun Liu
- , Lin Zeng
- , David M Irwin
- , Jiu-Lin Du
- , Yong-Gang Yao
- , Dong-Dong Wu
- & Ya-Ping Zhang
Cell Research 26 , 556–573

Rights & permissionsfor article Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication . Opens in a new window.
Research | 18 July 2016
Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations
- Hongjun Yu
- , Hideyuki Takeuchi
- , Megumi Takeuchi
- , Qun Liu
- , Joshua Kantharia
- , Robert S Haltiwanger
- & Huilin Li
Nature Chemical Biology 12 , 735–740

Rights & permissionsfor article Structural analysis of Notch-regulating Rumi reveals basis for pathogenic mutations . Opens in a new window.
Research | 5 February 2016 | Open
Miltirone exhibits antileukemic activity by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction pathways
- Ling Zhou
- , Lifeng Jiang
- , Maolei Xu
- , Qun Liu
- , Ning Gao
- , Ping Li
- & E-Hu Liu
Scientific Reports 6 , 1–10

Rights & permissionsfor article Miltirone exhibits antileukemic activity by ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction pathways . Opens in a new window.
Research | 22 September 2015 | Open
Atomic description of the immune complex involved in heparin-induced thrombocytopenia
- Zheng Cai
- , Serge V. Yarovoi
- , Zhiqiang Zhu
- , Lubica Rauova
- , Vincent Hayes
- , Tatiana Lebedeva
- , Qun Liu
- , Mortimer Poncz
- , Gowthami Arepally
- , Douglas B. Cines
- & Mark I. Greene
Nature Communications 6 , 1–10

Rights & permissionsfor article Atomic description of the immune complex involved in heparin-induced thrombocytopenia . Opens in a new window.
Research | 5 January 2016 | Open
Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis
- Chiara Ardiccioni
- , Oliver B. Clarke
- , David Tomasek
- , Habon A. Issa
- , Desiree C. von Alpen
- , Heather L. Pond
- , Surajit Banerjee
- , Kanagalaghatta R. Rajashankar
- , Qun Liu
- , Ziqiang Guan
- , Chijun Li
- , Brian Kloss
- , Renato Bruni
- , Edda Kloppmann
- , Burkhard Rost
- , M. Chiara Manzini
- , Lawrence Shapiro
- & Filippo Mancia
Nature Communications 7 , 1–9

Rights & permissionsfor article Structure of the polyisoprenyl-phosphate glycosyltransferase GtrB and insights into the mechanism of catalysis . Opens in a new window.
Research | 23 June 2015 | Open
Divergence of dim-light vision among bats (order: Chiroptera) as estimated by molecular and electrophysiological methods
- He-Qun Liu
- , Jing-Kuan Wei
- , Bo Li
- , Ming-Shan Wang
- , Rui-Qi Wu
- , Joshua D. Rizak
- , Li Zhong
- , Lu Wang
- , Fu-Qiang Xu
- , Yong-Yi Shen
- , Xin-Tian Hu
- & Ya-Ping Zhang
Scientific Reports 5 , 1–13

Rights & permissionsfor article Divergence of dim-light vision among bats (order: Chiroptera) as estimated by molecular and electrophysiological methods . Opens in a new window.
Research | 16 December 2014 | Open
Bacteria can mobilize nematode-trapping fungi to kill nematodes
- Xin Wang
- , Guo-Hong Li
- , Cheng-Gang Zou
- , Xing-Lai Ji
- , Tong Liu
- , Pei-Ji Zhao
- , Lian-Ming Liang
- , Jian-Ping Xu
- , Zhi-Qiang An
- , Xi Zheng
- , Yue-Ke Qin
- , Meng-Qing Tian
- , You-Yao Xu
- , Yi-Cheng Ma
- , Ze-Fen Yu
- , Xiao-Wei Huang
- , Shu-Qun Liu
- , Xue-Mei Niu
- , Jin-Kui Yang
- , Ying Huang
- & Ke-Qin Zhang
Nature Communications 5 , 1–9

Rights & permissionsfor article Bacteria can mobilize nematode-trapping fungi to kill nematodes . Opens in a new window.
Research | 26 May 2013
Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP
- Ruifeng Qi
- , Evans Boateng Sarbeng
- , Qun Liu
- , Katherine Quynh Le
- , Xinping Xu
- , Hongya Xu
- , Jiao Yang
- , Jennifer Li Wong
- , Christina Vorvis
- , Wayne A Hendrickson
- , Lei Zhou
- & Qinglian Liu
Nature Structural & Molecular Biology 20 , 900–907

Rights & permissionsfor article Allosteric opening of the polypeptide-binding site when an Hsp70 binds ATP . Opens in a new window.
Research | 24 December 2006
Structural basis for modulation of Kv4 K⁺ channels by auxiliary KChIP subunits
- Huayi Wang
- , Yan Yan
- , Qun Liu
- , Yanhua Huang
- , Yue Shen
- , Linjie Chen
- , Yi Chen
- , Qiuyue Yang
- , Quan Hao
- , KeWei Wang
- & Jijie Chai
Nature Neuroscience 10 , 32–39

Rights & permissionsfor article Structural basis for modulation of Kv4 K<sup>+</sup> channels by auxiliary KChIP subunits . Opens in a new window.