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Research | 13 August 2019 | Open
Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns
Nature Communications 10 , 1–15

Rights & permissionsfor article Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns . Opens in a new window.
Amendments and Corrections | 1 September 2005
Erratum: Building specificity with nonspecific RNA-binding proteins
- Ravinder Singh
- & Juan Valcárcel
Nature Structural & Molecular Biology 12 , 824–824

Rights & permissionsfor article Erratum: Building specificity with nonspecific RNA-binding proteins . Opens in a new window.
Amendments and Corrections | 1 August 2007
Erratum: U2AF-homology motif interactions are required for alternative splicing regulation by SPF45
- Lorenzo Corsini
- , Sophie Bonnal
- , Jerome Basquin
- , Michael Hothorn
- , Klaus Scheffzek
- , Juan Valcárcel
- & Michael Sattler
Nature Structural & Molecular Biology 14 , 785–785

Rights & permissionsfor article Erratum: U2AF-homology motif interactions are required for alternative splicing regulation by SPF45 . Opens in a new window.
Comments and Opinion | 18 June 2018
Elisa Izaurralde 1959–2018
- Matthias W. Hentze
- & Juan Valcárcel
Nature Structural & Molecular Biology 25 , 547–547

Rights & permissionsfor article Elisa Izaurralde 1959–2018 . Opens in a new window.
News and Views | 24 June 2016
Viral cell biology: Influenza raids the splicing store
- Juan Valcárcel
- & Juan Ortín
Nature Microbiology 1 , 1–2

Rights & permissionsfor article Viral cell biology: Influenza raids the splicing store . Opens in a new window.
Research | 10 May 2016 | Open
The complete local genotype–phenotype landscape for the alternative splicing of a human exon
Nature Communications 7 , 1–8

Rights & permissionsfor article The complete local genotype–phenotype landscape for the alternative splicing of a human exon . Opens in a new window.
Research | 4 March 2019
A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons
- Antonio Torres-Méndez
- , Sophie Bonnal
- , Yamile Marquez
- , Jonathan Roth
- , Marta Iglesias
- , Jon Permanyer
- , Isabel Almudí
- , Dave O’Hanlon
- , Tanit Guitart
- , Matthias Soller
- , Anne-Claude Gingras
- , Fátima Gebauer
- , Fabian Rentzsch
- , Benjamin J. Blencowe
- , Juan Valcárcel
- & Manuel Irimia
Nature Ecology & Evolution 3 , 691–701

Rights & permissionsfor article A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons . Opens in a new window.
Research | 16 August 2009
Nucleosome positioning as a determinant of exon recognition
Nature Structural & Molecular Biology 16 , 996–1001

Rights & permissionsfor article Nucleosome positioning as a determinant of exon recognition . Opens in a new window.
News and Views | 17 December 2008
Spliceosome meets telomerase
- Sophie Bonnal
- & Juan Valcárcel
Nature 456 , 879–880

Rights & permissionsfor article Spliceosome meets telomerase . Opens in a new window.
News and Views | 5 May 2010
Breaking the second genetic code
- J. Ramón Tejedor
- & Juan Valcárcel
Nature 465 , 45–46

Rights & permissionsfor article Breaking the second genetic code . Opens in a new window.
Research | 11 March 1993
The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA
Nature 362 , 171–175

Rights & permissionsfor article The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA . Opens in a new window.
News and Views | 1 July 2007
Powering a two-stroke RNA engine
- Josep Vilardell
- & Juan Valcárcel
Nature Structural & Molecular Biology 14 , 574–576

Rights & permissionsfor article Powering a two-stroke RNA engine . Opens in a new window.
Research | 16 December 1999
Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF³⁵ and the 3′ splice site AG
Nature 402 , 838–841

Rights & permissionsfor article Inhibition of <i>msl-2</i> splicing by Sex-lethal reveals interaction between U2AF<sup>35</sup> and the 3′ splice site AG . Opens in a new window.
Correspondence | 1 September 2004
Estimating rates of alternative splicing in mammals and invertebrates
- E D Harrington
- , S Boue
- , Juan Valcarcel
- , Jens G Reich
- & Peer Bork
Nature Genetics 36 , 916–917

Rights & permissionsfor article Estimating rates of alternative splicing in mammals and invertebrates . Opens in a new window.
News and Views | 1 January 2003
Getting to the heart of a splicing enhancer
- Daniel Bilbao
- & Juan Valcárcel
Nature Structural & Molecular Biology 10 , 6–7

Rights & permissionsfor article Getting to the heart of a splicing enhancer . Opens in a new window.
Research | 17 December 2001
Alternative splicing and genome complexity
- David Brett
- , Heike Pospisil
- , Juan Valcárcel
- , Jens Reich
- & Peer Bork
Nature Genetics 30 , 29–30

Rights & permissionsfor article Alternative splicing and genome complexity . Opens in a new window.
Research | 21 December 2017 | Open
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1
Nature Communications 8 , 1–18

Rights & permissionsfor article Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1 . Opens in a new window.
Research | 13 December 2017 | Open
Molecular basis of differential 3′ splice site sensitivity to anti-tumor drugs targeting U2 snRNP
- Luisa Vigevani
- , André Gohr
- , Thomas Webb
- , Manuel Irimia
- & Juan Valcárcel
Nature Communications 8 , 1–15

Rights & permissionsfor article Molecular basis of differential 3′ splice site sensitivity to anti-tumor drugs targeting U2 snRNP . Opens in a new window.
Research | 24 February 2013
CPEB1 coordinates alternative 3′-UTR formation with translational regulation
Nature 495 , 121–125

Rights & permissionsfor article CPEB1 coordinates alternative 3′-UTR formation with translational regulation . Opens in a new window.
Reviews | 5 November 2012
The spliceosome as a target of novel antitumour drugs
Nature Reviews Drug Discovery 11 , 847–859

Rights & permissionsfor article The spliceosome as a target of novel antitumour drugs . Opens in a new window.
Research | 24 June 2007
U2AF-homology motif interactions are required for alternative splicing regulation by SPF45
- Lorenzo Corsini
- , Sophie Bonnal
- , Jerome Basquin
- , Michael Hothorn
- , Klaus Scheffzek
- , Juan Valcárcel
- & Michael Sattler
Nature Structural & Molecular Biology 14 , 620–629

Rights & permissionsfor article U2AF-homology motif interactions are required for alternative splicing regulation by SPF45 . Opens in a new window.
Reviews | 2 August 2005
Building specificity with nonspecific RNA-binding proteins
- Ravinder Singh
- & Juan Valcárcel
Nature Structural & Molecular Biology 12 , 645–653

Rights & permissionsfor article Building specificity with nonspecific RNA-binding proteins . Opens in a new window.
Research | 13 July 2011
Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF
- Cameron D. Mackereth
- , Tobias Madl
- , Sophie Bonnal
- , Bernd Simon
- , Katia Zanier
- , Alexander Gasch
- , Vladimir Rybin
- , Juan Valcárcel
- & Michael Sattler
Nature 475 , 408–411

Rights & permissionsfor article Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF . Opens in a new window.

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Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns

Erratum: Building specificity with nonspecific RNA-binding proteins

Erratum: U2AF-homology motif interactions are required for alternative splicing regulation by SPF45

Elisa Izaurralde 1959–2018

Viral cell biology: Influenza raids the splicing store

The complete local genotype–phenotype landscape for the alternative splicing of a human exon

A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons

Nucleosome positioning as a determinant of exon recognition

Spliceosome meets telomerase

Breaking the second genetic code

The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA

Powering a two-stroke RNA engine

Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF³⁵ and the 3′ splice site AG

Estimating rates of alternative splicing in mammals and invertebrates

Getting to the heart of a splicing enhancer

Alternative splicing and genome complexity

Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1

Molecular basis of differential 3′ splice site sensitivity to anti-tumor drugs targeting U2 snRNP

CPEB1 coordinates alternative 3′-UTR formation with translational regulation

The spliceosome as a target of novel antitumour drugs

U2AF-homology motif interactions are required for alternative splicing regulation by SPF45

Building specificity with nonspecific RNA-binding proteins

Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF

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