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Amendments and Corrections | 19 September 2018
Correction: Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia
- S. Degryse
- , C. E. de Bock
- , S. Demeyer
- , I. Govaerts
- , S. Bornschein
- , D. Verbeke
- , K. Jacobs
- , S. Binos
- , D. A. Skerrett-Byrne
- , H. C. Murray
- , N. M. Verrills
- , P. Van Vlierberghe
- , J. Cools
- & M. D. Dun
Leukemia 32 , 2731–2731

Rights & permissionsfor article Correction: Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia . Opens in a new window.
8 March 2016 | Open
Generation of the Fip1l1–Pdgfra fusion gene using CRISPR/Cas genome editing
- M Vanden Bempt
- , S Demeyer
- , N Mentens
- , E Geerdens
- , C E De Bock
- , I Wlodarska
- & J Cools
Leukemia 30 , 1913–1916

Rights & permissionsfor article Generation of the <i>Fip1l1–Pdgfra</i> fusion gene using CRISPR/Cas genome editing . Opens in a new window.
Research | 29 October 1998
The high-fat phenotype: Is leptin involved in the adaptive response to a high fat (high energy) diet?
- J Cooling
- , J Barth
- & J Blundell
International Journal of Obesity 22 , 1132–1135

Rights & permissionsfor article The high-fat phenotype: Is leptin involved in the adaptive response to a high fat (high energy) diet? . Opens in a new window.
28 July 1998
Differences in energy expenditure and substrate oxidation between habitual high fat and low fat consumers (phenotypes)
- J Cooling
- & J Blundell
International Journal of Obesity 22 , 612–618

Rights & permissionsfor article Differences in energy expenditure and substrate oxidation between habitual high fat and low fat consumers (phenotypes) . Opens in a new window.
25 October 2001
High-fat and low-fat phenotypes: habitual eating of high- and low-fat foods not related to taste preference for fat
- J Cooling
- & JE Blundell
European Journal of Clinical Nutrition 55 , 1016–1021

Rights & permissionsfor article High-fat and low-fat phenotypes: habitual eating of high- and low-fat foods not related to taste preference for fat . Opens in a new window.
Research | 12 February 2009
FIP1L1-PDGFRα D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRα T674I eosinophilic leukemia with single agent sorafenib
- E Lierman
- , L Michaux
- , E Beullens
- , P Pierre
- , P Marynen
- , J Cools
- & P Vandenberghe
Leukemia 23 , 845–851

Rights & permissionsfor article FIP1L1-PDGFRα D842V, a novel panresistant mutant, emerging after treatment of FIP1L1-PDGFRα T674I eosinophilic leukemia with single agent sorafenib . Opens in a new window.
24 May 2007
Interstitial del(14)(q) involving IGH: a novel recurrent aberration in B-NHL
- H Pospisilova
- , M Baens
- , L Michaux
- , M Stul
- , P Van Hummelen
- , P Van Loo
- , J Vermeesch
- , M Jarosova
- , Z Zemanova
- , K Michalova
- , I Van den Berghe
- , H D Alexander
- , A Hagemeijer
- , P Vandenberghe
- , J Cools
- , C De Wolf-Peeters
- , P Marynen
- & I Wlodarska
Leukemia 21 , 2079–2083

Rights & permissionsfor article Interstitial del(14)(q) involving <i>IGH</i>: a novel recurrent aberration in B-NHL . Opens in a new window.
17 January 2012
Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases
- E Lierman
- , S Smits
- , J Cools
- , B Dewaele
- , M Debiec-Rychter
- & P Vandenberghe
Leukemia 26 , 1693–1695

Rights & permissionsfor article Ponatinib is active against imatinib-resistant mutants of FIP1L1-PDGFRA and KIT, and against FGFR1-derived fusion kinases . Opens in a new window.
5 October 2006
Transition from EML1-ABL1 to NUP214-ABL1 positivity in a patient with acute T-lymphoblastic leukemia
- K De Keersmaecker
- , I Lahortiga
- , C Graux
- , P Marynen
- , J Maertens
- , J Cools
- & P Vandenberghe
Leukemia 20 , 2202–2204

Rights & permissionsfor article Transition from <i>EML1-ABL1</i> to <i>NUP214-ABL1</i> positivity in a patient with acute T-lymphoblastic leukemia . Opens in a new window.
1 January 1998
Retinal neovascularisation and posterior penetrating ocular injury
- R D Bourke
- , R J Cooling
- & J P Bolger
Eye 12 , 147–148

Rights & permissionsfor article Retinal neovascularisation and posterior penetrating ocular injury . Opens in a new window.
14 March 2003
Vitreous surgery in the management of chronic endogenous posterior uveitis
- R A Scott
- , R J Haynes
- , G M Orr
- , R J Cooling
- , C E Pavésio
- & D G Charteris
Eye 17 , 221–227

Rights & permissionsfor article Vitreous surgery in the management of chronic endogenous posterior uveitis . Opens in a new window.
15 February 2007
A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome
- R La Starza
- , R Rosati
- , G Roti
- , P Gorello
- , A Bardi
- , B Crescenzi
- , V Pierini
- , O Calabrese
- , M Baens
- , C Folens
- , J Cools
- , P Marynen
- , M F Martelli
- , C Mecucci
- & A Cuneo
Leukemia 21 , 830–833

Rights & permissionsfor article A new NDE1/PDGFRB fusion transcript underlying chronic myelomonocytic leukaemia in Noonan Syndrome . Opens in a new window.
Research | 1 July 1987
Retinal relieving incisions
- P M Jacobs
- , R J Cooling
- , P K Leaver
- & D McLeod
Eye 1 , 500–503

Rights & permissionsfor article Retinal relieving incisions . Opens in a new window.
Research | 1 September 1988
Toxocariasis: A practical approach to management of ocular disease
- W J Dinning
- , S H Gillespie
- , R J Cooling
- & R M Maizels
Eye 2 , 580–582

Rights & permissionsfor article Toxocariasis: A practical approach to management of ocular disease . Opens in a new window.
Correspondence | 30 August 2002
The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma
- J Dierlamm
- , EM Murga Penas
- , M Daibata
- , H Tagushi
- , K Hinz
- , M Baens
- , J Cools
- , G Schilling
- , L Michaux
- , P Marynen
- , I Miyoshi
- & DK Hossfeld
Leukemia 16 , 1863–1864

Rights & permissionsfor article The novel t(11;12;18)(q21;q13;q21) represents a variant translocation of the t(11;18)(q21;q21) associated with MALT-type lymphoma . Opens in a new window.
Research | 11 September 2008
Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases
- K De Keersmaecker
- , M Versele
- , J Cools
- , G Superti-Furga
- & O Hantschel
Leukemia 22 , 2208–2216

Rights & permissionsfor article Intrinsic differences between the catalytic properties of the oncogenic NUP214-ABL1 and BCR-ABL1 fusion protein kinases . Opens in a new window.
11 January 2007
FIP1L1-PDGFRA in chronic eosinophilic leukemia and BCR-ABL1 in chronic myeloid leukemia affect different leukemic cells
- B Crescenzi
- , A Chase
- , R La Starza
- , D Beacci
- , V Rosti
- , A Gallì
- , G Specchia
- , M F Martelli
- , P Vandenberghe
- , J Cools
- , A V Jones
- , N C P Cross
- , P Marynen
- & C Mecucci
Leukemia 21 , 397–402

Rights & permissionsfor article <i>FIP1L1-PDGFRA</i> in chronic eosinophilic leukemia and <i>BCR-ABL1</i> in chronic myeloid leukemia affect different leukemic cells . Opens in a new window.
4 December 2000
Lean male high- and low-fat phenotypes—different routes for achieving energy balance
- J Cooling
- & JE Blundell
International Journal of Obesity 24 , 1561–1566

Rights & permissionsfor article Lean male high- and low-fat phenotypes—different routes for achieving energy balance . Opens in a new window.
1 January 1987
Retinal detachment following Nd:YAG posterior capsulotomy
- L A Ficker
- , S Vickers
- , M R C Capon
- , J Mellerio
- & R J Cooling
Eye 1 , 86–89

Rights & permissionsfor article Retinal detachment following Nd:YAG posterior capsulotomy . Opens in a new window.
1 January 1987
Intraocular argon laser photocoagulation
- R W Acheson
- , M Capon
- , R J Cooling
- , P K Leaver
- , J Marshall
- & D McLeod
Eye 1 , 97–105

Rights & permissionsfor article Intraocular argon laser photocoagulation . Opens in a new window.
Research | 1 May 1987
Ocular injuries associated with the use of airguns
Eye 1 , 422–429

Rights & permissionsfor article Ocular injuries associated with the use of airguns . Opens in a new window.
8 December 2005
Chronic myeloproliferative disorders: a tyrosine kinase tale
- K De Keersmaecker
- & J Cools
Leukemia 20 , 200–205

Rights & permissionsfor article Chronic myeloproliferative disorders: a tyrosine kinase tale . Opens in a new window.
Research | 4 May 2006
Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCRβ locus rearrangements and putative new T-cell oncogenes
- B Cauwelier
- , N Dastugue
- , J Cools
- , B Poppe
- , C Herens
- , A De Paepe
- , A Hagemeijer
- & F Speleman
Leukemia 20 , 1238–1244

Rights & permissionsfor article Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of <i>TCRβ</i> locus rearrangements and putative new T-cell oncogenes . Opens in a new window.
1 March 2000
Conservative management of double penetrating ocular injuries
Eye 14 , 249–251

Rights & permissionsfor article Conservative management of double penetrating ocular injuries . Opens in a new window.
Comments and Opinion | 21 October 2004
KIAA1509 is a novel PDGFRB fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32)
- R L Levine
- , M Wadleigh
- , D W Sternberg
- , I Wlodarska
- , I Galinsky
- , R M Stone
- , D J DeAngelo
- , D Gary Gilliland
- & J Cools
Leukemia 19 , 27–30

Rights & permissionsfor article <i>KIAA1509</i> is a novel <i>PDGFRB</i> fusion partner in imatinib-responsive myeloproliferative disease associated with a t(5;14)(q33;q32) . Opens in a new window.
Research | 1 July 1996
Retinal detachment complicating scleral-sutured posterior chamber intraocular lens surgery
Eye 10 , 501–508

Rights & permissionsfor article Retinal detachment complicating scleral-sutured posterior chamber intraocular lens surgery . Opens in a new window.
Research | 12 September 2004
Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia
- C. Graux
- , J. Cools
- , C. Melotte
- , H. Quentmeier
- , A. Ferrando
- , R. Levine
- , J.R. Vermeesch
- , M. Stul
- , B. Dutta
- , N. Boeckx
- , A. Bosly
- , P. Heimann
- , A. Uyttebroeck
- , N. Mentens
- , R. Somers
- , R.A.F. MacLeod
- , H.G. Drexler
- , A.T. Look
- , D.G. Gilliland
- , L. Michaux
- , P. Vandenberghe
- , I. Wlodarska
- , Peter Marynen
- & Anne Hagemeijer
Nature Genetics 36 , 1084–1089

Rights & permissionsfor article Fusion of <i>NUP214</i> to <i>ABL1</i> on amplified episomes in T-cell acute lymphoblastic leukemia . Opens in a new window.
1 May 1998
Vitreolensectomy in Marfan's syndrome
Eye 12 , 412–416

Rights & permissionsfor article Vitreolensectomy in Marfan's syndrome . Opens in a new window.
3 April 1998
Are high-fat and low-fat consumers distinct phenotypes? differences in the subjective and behavioural response to energy and nutrient challenges
- J Cooling
- & J Blundell
European Journal of Clinical Nutrition 52 , 193–201

Rights & permissionsfor article Are high-fat and low-fat consumers distinct phenotypes? differences in the subjective and behavioural response to energy and nutrient challenges . Opens in a new window.
Correspondence | 25 November 2004
e6-a2 BCR-ABL1 fusion in T-cell acute lymphoblastic leukemia
- H Quentmeier
- , J Cools
- , R A F MacLeod
- , P Marynen
- , C C Uphoff
- & H G Drexler
Leukemia 19 , 295–296

Rights & permissionsfor article e6-a2 <i>BCR-ABL1</i> fusion in T-cell acute lymphoblastic leukemia . Opens in a new window.
15 December 2005
Cryptic chromosomal aberrations waiting to be discovered
- I Lahortiga
- & J Cools
Leukemia 20 , 210–211

Rights & permissionsfor article Cryptic chromosomal aberrations waiting to be discovered . Opens in a new window.
1 November 1995
Letter
Eye 9 , 813–814

Rights & permissionsfor article Letter . Opens in a new window.
19 February 2004
Clinical and molecular features of FIP1L1-PDFGRA (+) chronic eosinophilic leukemias
- P Vandenberghe
- , I Wlodarska
- , L Michaux
- , P Zachée
- , M Boogaerts
- , D Vanstraelen
- , M-C Herregods
- , A Van Hoof
- , D Selleslag
- , F Roufosse
- , M Maerevoet
- , G Verhoef
- , J Cools
- , D G Gilliland
- , A Hagemeijer
- & P Marynen
Leukemia 18 , 734–742

Rights & permissionsfor article Clinical and molecular features of <i>FIP1L1-PDFGRA</i> (+) chronic eosinophilic leukemias . Opens in a new window.
Research | 1 May 1995
Retinal detachment and giant retinal tears in aniridia
- J G F Dowler
- , C J Lyons
- & R J Cooling
Eye 9 , 268–270

Rights & permissionsfor article Retinal detachment and giant retinal tears in aniridia . Opens in a new window.
Research | 29 October 2010
PHF6 mutations in adult acute myeloid leukemia
- P Van Vlierberghe
- , J Patel
- , O Abdel-Wahab
- , C Lobry
- , C V Hedvat
- , M Balbin
- , C Nicolas
- , A R Payer
- , H F Fernandez
- , M S Tallman
- , E Paietta
- , A Melnick
- , P Vandenberghe
- , F Speleman
- , I Aifantis
- , J Cools
- , R Levine
- & A Ferrando
Leukemia 25 , 130–134

Rights & permissionsfor article <i>PHF6</i> mutations in adult acute myeloid leukemia . Opens in a new window.
Research | 1 November 1996
Giant retinal tear and retinal detachment with underlying retinitis pigmentosa and hearing loss
Eye 10 , 697–700

Rights & permissionsfor article Giant retinal tear and retinal detachment with underlying retinitis pigmentosa and hearing loss . Opens in a new window.
Research | 10 April 2008
Activity of tyrosine kinase inhibitors against human NUP214-ABL1-positive T cell malignancies
- A Quintás-Cardama
- , W Tong
- , T Manshouri
- , F Vega
- , P A Lennon
- , J Cools
- , D G Gilliland
- , F Lee
- , J Cortes
- , H Kantarjian
- & G Garcia-Manero
Leukemia 22 , 1117–1124

Rights & permissionsfor article Activity of tyrosine kinase inhibitors against human <i>NUP214-ABL1</i>-positive T cell malignancies . Opens in a new window.
Research | 1 November 1992
Four-quadrant local anaesthesia technique for vitreoretinal surgery
- J D Stevens
- , W A Franks
- , G Orr
- , P K Leaver
- & R J Cooling
Eye 6 , 583–586

Rights & permissionsfor article Four-quadrant local anaesthesia technique for vitreoretinal surgery . Opens in a new window.
Research | 20 November 2017 | Open
Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T-cell model system
- S Bornschein
- , S Demeyer
- , R Stirparo
- , O Gielen
- , C Vicente
- , E Geerdens
- , B Ghesquière
- , S Aerts
- , J Cools
- & C E de Bock
Leukemia 32 , 941–951

Rights & permissionsfor article Defining the molecular basis of oncogenic cooperation between TAL1 expression and Pten deletion in T-ALL using a novel pro-T-cell model system . Opens in a new window.
Research | 24 July 2017
The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling
- T Girardi
- , S Vereecke
- , S O Sulima
- , Y Khan
- , L Fancello
- , J W Briggs
- , C Schwab
- , J Op de Beeck
- , J Verbeeck
- , J Royaert
- , E Geerdens
- , C Vicente
- , S Bornschein
- , C J Harrison
- , J P Meijerink
- , J Cools
- , J D Dinman
- , K R Kampen
- & K De Keersmaecker
Leukemia 32 , 809–819

Rights & permissionsfor article The T-cell leukemia-associated ribosomal RPL10 R98S mutation enhances JAK-STAT signaling . Opens in a new window.
Research | 30 August 2017 | Open
Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia
- S Degryse
- , C E de Bock
- , S Demeyer
- , I Govaerts
- , S Bornschein
- , D Verbeke
- , K Jacobs
- , S Binos
- , D A Skerrett-Byrne
- , H C Murray
- , N M Verrills
- , P Van Vlierberghe
- , J Cools
- & M D Dun
Leukemia 32 , 788–800

Rights & permissionsfor article Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia . Opens in a new window.
Research | 25 June 2015
Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia
- K Durinck
- , W Van Loocke
- , J Van der Meulen
- , I Van de Walle
- , M Ongenaert
- , P Rondou
- , A Wallaert
- , C E de Bock
- , N Van Roy
- , B Poppe
- , J Cools
- , J Soulier
- , T Taghon
- , F Speleman
- & P Van Vlierberghe
Leukemia 29 , 2317–2327

Rights & permissionsfor article Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia . Opens in a new window.
Research | 3 May 2011
Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice
- J P R Jacobsen
- , W B Siesser
- , B D Sachs
- , S Peterson
- , M J Cools
- , V Setola
- , J H A Folgering
- , G Flik
- & M G Caron
Molecular Psychiatry 17 , 694–704

Rights & permissionsfor article Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in tryptophan hydroxylase 2 (Tph2) loss-of-function mice . Opens in a new window.
27 January 2005
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
- F Speleman
- , B Cauwelier
- , N Dastugue
- , J Cools
- , B Verhasselt
- , B Poppe
- , N Van Roy
- , J Vandesompele
- , C Graux
- , A Uyttebroeck
- , M Boogaerts
- , B De Moerloose
- , Y Benoit
- , D Selleslag
- , J Billiet
- , A Robert
- , F Huguet
- , P Vandenberghe
- , A De Paepe
- , P Marynen
- & A Hagemeijer
Leukemia 19 , 358–366

Rights & permissionsfor article A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of <i>HOXA10</i> and <i>HOXA11</i> in a subset of T-cell acute lymphoblastic leukemias . Opens in a new window.
Research | 12 October 2006
Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the TCRβ-HOXA rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique
- B Cauwelier
- , H Cavé
- , C Gervais
- , M Lessard
- , C Barin
- , C Perot
- , J Van den Akker
- , F Mugneret
- , C Charrin
- , M P Pagès
- , M-J Grégoire
- , P Jonveaux
- , M Lafage-Pochitaloff
- , M J Mozzicconacci
- , C Terré
- , I Luquet
- , P Cornillet-Lefebvre
- , B Laurence
- , G Plessis
- , C Lefebvre
- , D Leroux
- , H Antoine-Poirel
- , C Graux
- , L Mauvieux
- , P Heimann
- , C Chalas
- , E Clappier
- , B Verhasselt
- , Y Benoit
- , B D Moerloose
- , B Poppe
- , N Van Roy
- , K D Keersmaecker
- , J Cools
- , F Sigaux
- , J Soulier
- , A Hagemeijer
- , A D Paepe
- , N Dastugue
- , R Berger
- & F Speleman
Leukemia 21 , 121–128

Rights & permissionsfor article Clinical, cytogenetic and molecular characteristics of 14 T-ALL patients carrying the <i>TCRβ-HOXA</i> rearrangement: a study of the Groupe Francophone de Cytogénétique Hématologique . Opens in a new window.
9 October 2008
Five years since the discovery of FIP1L1–PDGFRA: what we have learned about the fusion and other molecularly defined eosinophilias
- J Gotlib
- & J Cools
Leukemia 22 , 1999–2010

Rights & permissionsfor article Five years since the discovery of <i>FIP1L1–PDGFRA</i>: what we have learned about the fusion and other molecularly defined eosinophilias . Opens in a new window.
6 July 2006
Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast
- C Graux
- , J Cools
- , L Michaux
- , P Vandenberghe
- & A Hagemeijer
Leukemia 20 , 1496–1510

Rights & permissionsfor article Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: from thymocyte to lymphoblast . Opens in a new window.
Research | 16 October 2008
Heterogeneous patterns of amplification of the NUP214-ABL1 fusion gene in T-cell acute lymphoblastic leukemia
- C Graux
- , M Stevens-Kroef
- , M Lafage
- , N Dastugue
- , C J Harrison
- , F Mugneret
- , K Bahloula
- , S Struski
- , M J Grégoire
- , N Nadal
- , E Lippert
- , S Taviaux
- , A Simons
- , R P Kuiper
- , A V Moorman
- , K Barber
- , A Bosly
- , L Michaux
- , P Vandenberghe
- , I Lahortiga
- , K De Keersmaecker
- , I Wlodarska
- , J Cools
- , A Hagemeijer
- & H A Poirel
Leukemia 23 , 125–133

Rights & permissionsfor article Heterogeneous patterns of amplification of the <i>NUP214-ABL1</i> fusion gene in T-cell acute lymphoblastic leukemia . Opens in a new window.