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Research | 19 July 2019 | Open
β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer
- Piera Tocci
- , Roberta Cianfrocca
- , Valeriana Di Castro
- , Laura Rosanò
- , Andrea Sacconi
- , Sara Donzelli
- , Silvia Bonfiglio
- , Gabriele Bucci
- , Enrico Vizza
- , Gabriella Ferrandina
- , Giovanni Scambia
- , Giovanni Tonon
- , Giovanni Blandino
- & Anna Bagnato
Nature Communications 10 , 1–15

Rights & permissionsfor article β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer . Opens in a new window.
20 January 1999
Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
Oncogene 18 , 477–485

Rights & permissionsfor article Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy . Opens in a new window.
4 July 2005
δEF1 repressor controls selectively p53 family members during differentiation
- Giulia Fontemaggi
- , Aymone Gurtner
- , Alexander Damalas
- , Antonio Costanzo
- , Yujiro Higashi
- , Ada Sacchi
- , Sabrina Strano
- , Giulia Piaggio
- & Giovanni Blandino
Oncogene 24 , 7273–7280

Rights & permissionsfor article δEF1 repressor controls selectively p53 family members during differentiation . Opens in a new window.
3 May 2004
HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function
Oncogene 23 , 5185–5192

Rights & permissionsfor article HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function . Opens in a new window.
20 February 2002
Monoclonal antibodies raised against Xenopus p53 interact with human p73
Oncogene 21 , 1304–1308

Rights & permissionsfor article Monoclonal antibodies raised against Xenopus p53 interact with human p73 . Opens in a new window.
Research | 24 June 1999
Interaction of c-Abl and p73α and their collaboration to induce apoptosis
- Reuven Agami
- , Giovanni Blandino
- , Moshe Oren
- & Yosef Shaul
Nature 399 , 809–813

Rights & permissionsfor article Interaction of c-Abl and p73α and their collaboration to induce apoptosis . Opens in a new window.
14 October 1998
Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs
- Yingcai Wang
- , Giovanni Blandino
- , Moshe Oren
- & David Givol
Oncogene 17 , 1923–1930

Rights & permissionsfor article Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs . Opens in a new window.
Research | 2 October 2002
The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults
- Paola Zacchi
- , Monica Gostissa
- , Takafumi Uchida
- , Clio Salvagno
- , Fabio Avolio
- , Stefano Volinia
- , Ze'ev Ronai
- , Giovanni Blandino
- , Claudio Schneider
- & Giannino Del Sal
Nature 419 , 853–857

Rights & permissionsfor article The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults . Opens in a new window.
27 April 1999
Induced p21^waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin
Oncogene 18 , 2643–2649

Rights & permissionsfor article Induced p21waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin . Opens in a new window.
31 July 1997
Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells
Oncogene 15 , 607–611

Rights & permissionsfor article Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells . Opens in a new window.
Research | 8 January 2019 | Open
Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells
- Teresa Bellissimo
- , Claudia Tito
- , Federica Ganci
- , Andrea Sacconi
- , Silvia Masciarelli
- , Giuseppe Di Martino
- , Natale Porta
- , Mirko Cirenza
- , Melissa Sorci
- , Luciana De Angelis
- , Paolo Rosa
- , Antonella Calogero
- , Alessandro Fatica
- , Vincenzo Petrozza
- , Giulia Fontemaggi
- , Giovanni Blandino
- & Francesco Fazi
Cell Death & Disease 10 , 1–12

Rights & permissionsfor article Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells . Opens in a new window.
Research | 11 September 2018 | Open
Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model
- Laura Belloni
- , Silvia Di Cocco
- , Francesca Guerrieri
- , Abigail D. G. Nunn
- , Silvia Piconese
- , Debora Salerno
- , Barbara Testoni
- , Claudio Pulito
- , Federica Mori
- , Matteo Pallocca
- , Andrea Sacconi
- , Elisa Vivoli
- , Fabio Marra
- , Sabrina Strano
- , Giovanni Blandino
- , Massimo Levrero
- & Natalia Pediconi
Scientific Reports 8 , 1–12

Rights & permissionsfor article Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model . Opens in a new window.
Research | 9 January 2018
HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome
Oncogene 37 , 1369–1385

Rights & permissionsfor article HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome . Opens in a new window.
Research | 4 July 2017 | Open
Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities
- Claudio Pulito
- , Federica Mori
- , Andrea Sacconi
- , Frauke Goeman
- , Maria Ferraiuolo
- , Patrizia Pasanisi
- , Carlo Campagnoli
- , Franco Berrino
- , Maurizio Fanciulli
- , Rebecca J Ford
- , Massimo Levrero
- , Natalia Pediconi
- , Ludovica Ciuffreda
- , Michele Milella
- , Gregory R Steinberg
- , Mario Cioce
- , Paola Muti
- , Sabrina Strano
- & Giovanni Blandino
Cell Discovery 3 , 1–19

Rights & permissionsfor article Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities . Opens in a new window.
Research | 21 July 2017
Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence
- Federica Ganci
- , Andrea Sacconi
- , Valentina Manciocco
- , Renato Covello
- , Maria Benevolo
- , Francesca Rollo
- , Sabrina Strano
- , Sara Valsoni
- , Silvio Bicciato
- , Giuseppe Spriano
- , Paola Muti
- , Giulia Fontemaggi
- & Giovanni Blandino
Modern Pathology 30 , 1387–1401

Rights & permissionsfor article Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence . Opens in a new window.
Research | 21 February 2017 | Open
PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer
- Michele Milella
- , Italia Falcone
- , Fabiana Conciatori
- , Silvia Matteoni
- , Andrea Sacconi
- , Teresa De Luca
- , Chiara Bazzichetto
- , Vincenzo Corbo
- , Michele Simbolo
- , Isabella Sperduti
- , Antonina Benfante
- , Anais Del Curatolo
- , Ursula Cesta Incani
- , Federico Malusa
- , Adriana Eramo
- , Giovanni Sette
- , Aldo Scarpa
- , Marina Konopleva
- , Michael Andreeff
- , James Andrew McCubrey
- , Giovanni Blandino
- , Matilde Todaro
- , Giorgio Stassi
- , Ruggero De Maria
- , Francesco Cognetti
- , Donatella Del Bufalo
- & Ludovica Ciuffreda
Scientific Reports 7 , 1–15

Rights & permissionsfor article PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer . Opens in a new window.
Research | 11 May 2014
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers
- Francesca Cottini
- , Teru Hideshima
- , Chunxiao Xu
- , Martin Sattler
- , Martina Dori
- , Luca Agnelli
- , Elisa ten Hacken
- , Maria Teresa Bertilaccio
- , Elena Antonini
- , Antonino Neri
- , Maurilio Ponzoni
- , Magda Marcatti
- , Paul G Richardson
- , Ruben Carrasco
- , Alec C Kimmelman
- , Kwok-Kin Wong
- , Federico Caligaris-Cappio
- , Giovanni Blandino
- , W Michael Kuehl
- , Kenneth C Anderson
- & Giovanni Tonon
Nature Medicine 20 , 599–606

Rights & permissionsfor article Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers . Opens in a new window.
Research | 29 May 2012
Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC
- Giovanni Blandino
- , Mariacristina Valerio
- , Mario Cioce
- , Federica Mori
- , Luca Casadei
- , Claudio Pulito
- , Andrea Sacconi
- , Francesca Biagioni
- , Giancarlo Cortese
- , Sergio Galanti
- , Cesare Manetti
- , Gennaro Citro
- , Paola Muti
- & Sabrina Strano
Nature Communications 3 , 1–11

Rights & permissionsfor article Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC . Opens in a new window.
Research | 27 September 2009
The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis
- Giulia Fontemaggi
- , Stefania Dell'Orso
- , Daniela Trisciuoglio
- , Tal Shay
- , Elisa Melucci
- , Francesco Fazi
- , Irene Terrenato
- , Marcella Mottolese
- , Paola Muti
- , Eytan Domany
- , Donatella Del Bufalo
- , Sabrina Strano
- & Giovanni Blandino
Nature Structural & Molecular Biology 16 , 1086–1093

Rights & permissionsfor article The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis . Opens in a new window.
27 November 1997
Induction of Mdm2 and enhancement of cell survival by bFGF
- Eitan Shaulian
- , Dalia Resnitzky
- , Ohad Shifman
- , Giovanni Blandino
- , Abraham Amsterdam
- , Avner Yayon
- & Moshe Oren
Oncogene 15 , 2717–2725

Rights & permissionsfor article Induction of Mdm2 and enhancement of cell survival by bFGF . Opens in a new window.

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β-arrestin1/YAP/mutant p53 complexes orchestrate the endothelin A receptor signaling in high-grade serous ovarian cancer

Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy

δEF1 repressor controls selectively p53 family members during differentiation

HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function

Monoclonal antibodies raised against Xenopus p53 interact with human p73

Interaction of c-Abl and p73α and their collaboration to induce apoptosis

Induced p53 expression in lung cancer cell line promotes cell senescence and differentially modifies the cytotoxicity of anti-cancer drugs

The prolyl isomerase Pin1 reveals a mechanism to control p53 functions after genotoxic insults

Induced p21^waf expression in H1299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin

Oncogenes belonging to the CSF-1 transduction pathway direct p53 tumor suppressor effects to monocytic differentiation in 32D cells

Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells

Targeting a phospho-STAT3-miRNAs pathway improves vesicular hepatic steatosis in an in vitro and in vivo model

HSP90 inhibition alters the chemotherapy-driven rearrangement of the oncogenic secretome

Metformin-induced ablation of microRNA 21-5p releases Sestrin-1 and CAB39L antitumoral activities

Altered peritumoral microRNA expression predicts head and neck cancer patients with a high risk of recurrence

PTEN status is a crucial determinant of the functional outcome of combined MEK and mTOR inhibition in cancer

Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers

Metformin elicits anticancer effects through the sequential modulation of DICER and c-MYC

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis

Induction of Mdm2 and enhancement of cell survival by bFGF

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