The power stroke of the swinging cross-bridge model, via myosin-actin cycling
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The power stroke of the swinging cross-bridge model, via myosin-actin cycling
Actin (red) interacts with myosin, shown in globular form (pink) and a filament form (black line). The model shown is that of H. E. Huxley, modified to indicate bending (curved arrow) near the middle of the elongated cross bridge (subfragment 1, or S1) which provides the working stroke. This bending propels actin to the right approximately 10 nanometers (10 nm step). S2 tethers globular myosin to the thick filament (horizontal yellow line), which stays in place while the actin filament moves. Modified from Spudich (2001).
This image is linked to the following Scitable pages:
How do muscles contract? What molecules are necessary for a tissue to change its shape?
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