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The hSWI/SNF complex disrupts a nucleosome core structure in an ATP-dependent manner

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The hSWI/SNF complex disrupts a nucleosome core structure in an ATP-dependent manner
The ATP-dependent disruption of nucleosome (PH GAL41) by the hSWI/SNF complex. N, naked DNA; open circles, increased DNase 1 cleavage; closed circles, decreased DNase 1 cleavage. Ten base-pair repeats calculated from the 5' end of the DNA fragment are indicated on the left.

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Chromatin Remodeling and DNase 1 Sensitivity

When genes are coiled and compacted into chromatin, they're no longer accessible to transcription factors. So how does the cell know where to uncoil in a process called chromatin remodeling?

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