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T-loop.

  • Author: Jack Griffith

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T-loop.
The ends of mammalian chromosomes end in giant duplex loops, called t-loops. In this photo, telomeric DNA from cultured human tissue cells is shown arranged in a t-loop conformation.

This image is linked to the following Scitable pages:

Telomeres of Human Chromosomes

In the 1930s, Muller was surprised to note that telomeres were strangely resistant to mutagenic X-rays. Why are the unique properties of these chromosomal "end caps" so important?

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