RTK activation involves the joining together and phosphorylation of proteins.
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RTK activation involves the joining together and phosphorylation of proteins.
On the left, an unactivated RTK receptor (pink) encounters a ligand (red). Upon binding, the receptor forms a complex of proteins that phosphorylate each other. In turn, this phosphorylation affects other proteins in the cell that change gene transcription (not shown).
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Signal binding to membrane receptor tyrosine kinases (RTKs) activates an enzyme called a kinase. Learn how kinases initiate a signaling cascade that relays information to the nucleus.
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