Many of the mammalian cell cycle genes were first identified and studied in yeast.
- Author: Kathleen Collins,Tyler Jacks,Nikola P. Pavletich
Keywords
Flag Inappropriate
Delete Content
Many of the mammalian cell cycle genes were first identified and studied in yeast.
In each cell division cycle, chromosomes are replicated once (DNA synthesis or S-phase) and segregated to create two genetically identical daughter cells (mitosis or M-phase). These events are spaced by intervals of growth and reorganization (gap phases G1 and G2). Cells can stop cycling after division, entering a state of quiescence (G0). Commitment to traverse an entire cycle is made in late G1. Progress through the cycle is accomplished in part by the regulated activity of numerous CDK-cyclin complexes.
This image is linked to the following Scitable pages:
Think yeast just belongs in the kitchen? Mitosis in baker's yeast can also tell us about mutations that cause cancer.
Comments
CloseComments
Please Post Your Comment