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If the number of bases removed or inserted from a segment of DNA is not a multiple of three (a), a different sequence with a different set of reading frames is transcribed to mRNA (b).


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If the number of bases removed or inserted from a segment of DNA is not a multiple of three (a), a different sequence with a different set of reading frames is transcribed to mRNA (b).
If the number of bases removed or inserted from a segment of DNA is not a multiple of three (a), a different sequence with a different set of reading frames is transcribed to mRNA (b).

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Just like the mechanical components in cars or computers, the molecules inside a cell can sometimes malfunction. When this happens during DNA replication, the result is an unpredictable change in the nucleotide sequence of an organism's DNA. This process, called mutation, is part of what determines changes in the characteristics of populations across multiple generations.

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