The 110 DCS blocks identified on the human genome are grouped according to their composition in terms of Tetraodon chromosomes, thus delineating 12 ancestral chromosomes containing 90 DCS blocks. The order of DCS within an ancestral chromosome is arbitrary. The 20 blocks denoted by the letters U, V, W, and Z could not be assigned to an ancestral chromosome because each has a unique composition, probably due to rearrangements in the human or Tetraodon genome.
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How are pufferfish helping us understand our own evolution? By mapping synteny in their short genome, scientists can find evolutionary patterns through this example of comparative genomics.
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