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Characterizing signals of selection in humans

  • Author: Stephen F. Schaffner ,Pardis C. Sabeti

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Characterizing signals of selection in humans
The process of identifying evolutionary adaptation involves many steps, from identifying signals of selection in the genome to finding and characterizing the target element and polymorphism. For the signals of selections found thus far, some have been fully elucidated, while others are only just being described. For most, we do not yet have a strong evolutionary explanation. Here are just a few examples of the signals identified thus far. The gray arrow represents that while convergent evolution greatly strengthens the case for selection, it is not always present. The * indicates new changes found in the previously identified gene.

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Are you lactose intolerant? Many people are. In fact, the ability to digest lactose may be an example of adaptive evolution in the human lineage.

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