CDKs, Plks and Aurora kinases are important kinase families in cell cycle regulation.
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CDKs, Plks and Aurora kinases are important kinase families in cell cycle regulation.
Different CDKs operate at different stages of the cell cycle and together make the driving force to direct the progression. Plks and Aurora kinases exert a fine spatiotemporal control of the cell cycle events in different ways, ranging from centrosome function, spindle assembly, and chromosome segregation to cytokinesis. Their mission is to maintain the fidelity of cell division.
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What regulates protein kinase activity during cell division? Interestingly, protein kinases phosphorylate each other as well as act on common targets.
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