Many concepts that are now commonly accepted were foreshadowed by Boveri, including cell-cycle checkpoints, oncogenes and tumour-suppressor genes, tumour predisposition, and the relationship between genetic instability
and cancer.
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In cancer, one of the leading causes of death in the US, cells divide wildly out of control. Can tumor suppressor genes and proto-oncogenes provide clues on how to stop this process?
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