Like in the auditory ossicle chain (A), which connects the tympanic membrane to the fluid-filled cochlea to convey vibrations, the basic features of adhesion receptors include a molecular chain of adaptor proteins connecting the adhesion receptor's cytoplasmic domains (B: integrins; C: cadherins) to the cell cytoskeleton.
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How do cells forming organs or repairing tissues know when to stop growing? Adhesion receptors act as molecular fingertips that sense the environment and then coordinate behaviors.
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