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April 07, 2013 | By:  Eric Sawyer
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#DROS2013 Day 4

Highlights from day 4:

Transcription factor talk from my (academic) aunt. I went to a talk by a grad student in the lab of my summer advisor's graduate advisor (my academic aunt?) on using bacterial 1-hybrid assays to catalog bHLH transcription factor motifs. Eventually, we should be able to have a motif for every transcription factor in flies.

Fly hearts double as kidneys. Not only does GFP tagged with a secretory sequence end up in the fly heart, but the heart also expresses orthologs of proteins that are kidney-specific in humans.

Cell-cell connections might serve as buffers for noisy gene expression. In the fly egg, ring canals maintain wide connections between populations of somatic cells. Proteins expressed in one cell can diffuse to others, perhaps maintaining homogeneity in the egg.

Undergrads rule! My friend and colleague Bethany gave the only undergraduate talk at the conference, on her work with microtubule severing proteins in the fly testis.

4 Comments
Comments
May 04, 2013 | 01:24 AM
Posted By:  Eric Sawyer
Sorry for the delayed response--That is in fact the correct abstract. The lab's page is here: http://sitemaker.umich.edu/han.zhe.lab/home_page

You can find a list of publications there if you are interested in learning more.
April 16, 2013 | 05:14 AM
Posted By:  Anjali A
i think that abstract is not the correct one. Can you tell me more about this topic??
April 12, 2013 | 12:40 AM
Posted By:  Eric Sawyer
Fly hearts serve some of the functions that kidneys do in other taxa. GFP fused to a secretory tag ends up in the heart, and the fly heart expresses proteins that are associated with the kidney in other species. I believe this is the abstract: http://www.dros-conf.org/2013/abstracts/text/f13531013.htm
April 10, 2013 | 11:55 AM
Posted By:  Anjali A
What did you mean by "Fly hearts double as kidneys"??
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