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Scientific American

January 1, 2004

1 min read

Decoding Schizophrenia

A fuller understanding of signaling in the brain of people with this disorder offers new hope for improved therapy

By Daniel C. Javitt and Joseph T. Coyle

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Recent Advances in the Phencyclidine Model of Schizophrenia. D. C. Javitt and S. R. Zukin in American Journal of Psychiatry, Vol. 148, No. 10, pages 1301-1308; October 1991.

Efficacy of High-Dose Glycine in the Treatment of Enduring Negative Symptoms of Schizophrenia. U. Heresco-Levy, D. C. Javitt, M. Ermilov, C. Mordel, G. Silipo and M. Lichtenstein in Archives of General Psychiatry, Vol. 56, No. 1, pages 29-36; January 1999.

The Emerging Role of Glutamate in the Pathophysiology and Treatment of Schizophrenia. D. C. Goff and J. T. Coyle in American Journal of Psychiatry, Vol. 158, No. 9, pages 1367?1377; September 2001.

Revolution #9. Directed by Tim McCann. Wellspring Media, 2001. VHS and DVD release, 2003.

More by Daniel C. Javitt and Joseph T. Coyle
Scientific American Magazine Vol 290 Issue 1This article was originally published with the title “Decoding Schizophrenia” in Scientific American Magazine Vol. 290 No. 1 ()
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