Welcome to RNAi Gateway

The RNAi Gateway provides a convenient portal into publications relevant to every aspect of RNAi from journals throughout Nature Publishing Group. The gateway was active between November 2008 and July 2011, and now provides an archive of RNAi related articles.

  • Latest Highlight

    Role for microRNAs in regulation of insulin sensitivity FREE

    Nature, 30 June 2011

    Markus Stoffel and colleagues have shown that microRNA 103 and microRNA 107 are negative regulators of insulin sensitivity. Silencing these microRNAs in obese mice improved glucose homeostasis and insulin sensitivity by preventing miRNA mediated inhibition of a key regulator of the insulin receptor, caveolin-1, which subsequently enhanced insulin signalling and insulin-stimulated glucose uptake. Gain of miR-103/107 function in either liver or fat tissue impaired glucose homeostasis. These two microRNAs could therefore serve as therapeutic targets for treating diabetes.

Current Content

Find out what's new in RNAi by browsing research reports, reviews, news and comment — all conveniently collected here from Nature Publishing Group's wide range of journals. To select the very latest developments by category, click on any of the links below.

  • Podcast

    30 October 2008

    Tune in to find out more about the expanding world of small RNAs. Get the low-down on where we find them, what we know (and don't know) about what they do and even how they evolved.