About this site

Why focus on RNAi?

RNA interference, which encompasses a variety of post-transcriptional gene-silencing mechanisms mediated by short RNA molecules, has emerged as a tremendously important research area in the past decade. Our knowledge about RNAi was originally confined to petunias and other plant species, but has since expanded to many other organisms. Its roles in development and disease are increasingly being appreciated, as is the diversity and complexity of the RNA molecules involved. In addition, many investigators now exploit RNAi as a tool for targeted gene knockdown, generating invaluable data at both a single-gene and genome-wide level. Also, the prospect of RNAi-based therapies is steadily becoming more realistic.

What is the Gateway's purpose?

In this RNAi Gateway, we aim to help readers navigate through primary literature and comments on RNAi published in NPG's research and review journals. You will find papers in all fields related to RNAi, including basic research about the biology and function of small RNA molecules and the complexes that process and utilize them, the application of RNAi as a technology for gene knockdowns and screening, and its development as a potential therapeutic. To facilitate targeted searching, the site allows you to browse material by organism or subject categories and to sign-up for periodic newsletter alerts and RSS feeds. The RNAi Gateway will be updated with new published content on a regular basis.

Our goal is to make this a site that you will find both stimulating and informative, so we welcome your feedback. Should you have any questions or suggestions, please email rnaigateway@nature.com.

RNAi Gateway editors: Angela Eggleston, Nathalie Le Bot, Nicole Rusk, Rachel Smallridge

Managing editor: Nick Campbell

Managing director: Steven Inchcoombe

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