Human organs-on-chips for disease modelling, drug development and personalized medicine
This Review summarizes how human organ chip systems have been used to model complex diseases and rare genetic disorders
This Review summarizes how human organ chip systems have been used to model complex diseases and rare genetic disorders
Plants have uniquely adapted to manage endoplasmic reticulum stress triggered by protein misfolding. The authors review the dynamics of gene expression regulation underlying the unfolded protein response in plants, highlighting recent insights provided by systems-level approaches and omics data.