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web focus Microarrays
Review
This library contains links to a number of recently published articles about Microarrays from across the Nature Publishing Group. Click on the article type required to the left or below.
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Research
Nature

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
Coleen T.  Murphy, Steven A. McCarroll, Cornelia I. Bargmann, Andrew Fraser, Ravi S. Kamath, Julie Ahringer, Hao Li  & Cynthia  Kenyon
Nature 424, 277-283  2003
Abstract  | Full Text (HTML/ PDF)

Genetics of gene expression surveyed in maize, mouse and man
Eric E.  Schadt, Stephanie A. Monks, Thomas A. Drake, Aldons J. Lusis, Nam Che, Veronica Colinayo, Thomas G. Ruff, Stephen B. Milligan, John R. Lamb, Guy Cavet, Peter S. Linsley, Mao Mao, Roland B. Stoughton  & Stephen H.  Friend
Nature 422, 297-302  2003
Abstract  | Full Text (HTML/ PDF)

Gene expression profiling predicts clinical outcome of breast cancer
Laura J. van 't Veer, Hongyue Dai, Marc J. van de Vijver, Yudong D. He, Augustinus A. M. Hart, Mao Mao, Hans L. Peterse, Karin van der Kooy, Matthew J. Marton, Anke T. Witteveen, George J. Schreiber, Ron M. Kerkhoven, Chris Roberts, Peter S. Linsley, René Bernards  & Stephen H.  Friend
Nature 415, 530-536  2002
Abstract  | Full Text (HTML/ PDF)

Experimental annotation of the human genome using microarray technology
D. D.  Shoemaker, E. E. Schadt, C. D. Armour, Y. D. He, P. Garrett-Engele, P. D. McDonagh, P. M. Loerch, A. Leonardson, P. Y. Lum, G. Cavet, L. F. Wu, S. J. Altschuler, S. Edwards, J. King, J. S. Tsang, G. Schimmack, J. M. Schelter, J. Koch, M. Ziman, M. J. Marton, B. Li, P. Cundiff, T. Ward, J. Castle, M. Krolewski, M. R. Meyer, M. Mao, J. Burchard, M. J. Kidd, H. Dai, J. W. Phillips, P. S. Linsley, R. Stoughton, S. Scherer  & M. S.  Boguski
Nature 409, 922-927  2001
Abstract  | Full Text (HTML/ PDF)

Nature Biotechnology

Integration of chemical-genetic and genetic interaction data links bioactive compounds to cellular target pathways
Ainslie B  Parsons, Rene L Brost, Huiming Ding, Zhijian Li, Chaoying Zhang, Bilal Sheikh, Grant W Brown, Patricia M Kane, Timothy R Hughes  & Charles  Boone
Nature Biotechnology 22, 62-69  2003
Abstract  | Full Text (HTML/ PDF)

Analyzing antibody specificity with whole proteome microarrays
Gregory A  Michaud, Michael Salcius, Fang Zhou, Rhonda Bangham, Jaclyn Bonin, Hong Guo, Michael Snyder, Paul F Predki  & Barry I  Schweitzer
Nature Biotechnology 21, 1509-1512  2003
Full Text (HTML/ PDF)

Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis
William H  Robinson, Paulo Fontoura, Byung J Lee, Henry E Neuman de Vegvar, Jennifer Tom, Rosetta Pedotti, Carla D DiGennaro, Dennis J Mitchell, Derek Fong, Peggy P-K Ho, Pedro J Ruiz, Emanual Maverakis, David B Stevens, Claude C A Bernard, Roland Martin, Vijay K Kuchroo, Johannes M van Noort, Claude P Genain, Sandra Amor, Tomas Olsson, Paul J Utz, Hideki Garren  & Lawrence  Steinman
Nature Biotechnology 21, 1033-1039  2003
Abstract  | Full Text (HTML/ PDF)

A model of molecular interactions on short oligonucleotide microarrays
Li  Zhang, Michael F Miles  & Kenneth D  Aldape
Nature Biotechnology 21, 818-821  2003
Full Text (HTML/ PDF)

Nature Genetics

DNA helicase gene interaction network defined using synthetic lethality analyzed by microarray
Siew Loon  Ooi, Daniel D Shoemaker  & Jef D  Boeke
Nature Genetics 35, 277-286  2003
Abstract  | Full Text (HTML/ PDF)

Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data
Eran  Segal, Michael Shapira, Aviv Regev, Dana Pe'er, David Botstein, Daphne Koller  & Nir  Friedman
Nature Genetics 34, 166-176  2003
Abstract  | Full Text (HTML/ PDF)

Gene expression phenotypic models that predict the activity of oncogenic pathways
Erich  Huang, Seiichi Ishida, Jennifer Pittman, Holly Dressman, Andrea Bild, Mark Kloos, Mark D'Amico, Richard G Pestell, Mike West  & Joseph R  Nevins
Nature Genetics 34, 226-230  2003
Abstract  | Full Text (HTML/ PDF)

Treatment-specific changes in gene expression discriminate in vivo drug response in human leukemia cells
Meyling H.  Cheok, Wenjian Yang, Ching-Hon Pui, James R. Downing, Cheng Cheng, Clayton W. Naeve, Mary V. Relling  & William E.  Evans
Nature Genetics 34, 85-90  2003
Abstract  | Full Text (HTML/ PDF)

Evolution of gene expression in the Drosophila melanogaster subgroup
Scott A.  Rifkin, Junhyong Kim  & Kevin P.  White
Nature Genetics 33, 138-144  2003
Abstract  | Full Text (HTML/ PDF)

A molecular signature of metastasis in primary solid tumors
Sridhar  Ramaswamy, Ken N. Ross, Eric S. Lander  & Todd R.  Golub
Nature Genetics 33, 49-54  2002
Abstract  | Full Text (HTML/ PDF)

Identifying distinct classes of bladder carcinoma using microarrays
Lars  Dyrskjøt, Thomas Thykjaer, Mogens Kruhøffer, Jens Ledet Jensen, Niels Marcussen, Stephen Hamilton-Dutoit, Hans Wolf  & Torben F.  Ørntoft
Nature Genetics 33, 90-96  2002
Abstract  | Full Text (HTML/ PDF)

Genome-wide DNA replication profile for Drosophila melanogaster: a link between transcription and replication timing
Dirk Schübeler, David Scalzo, Charles Kooperberg, Bas van Steensel, Jeffrey Delrow  & Mark  Groudine
Nature Genetics 32, 438-442  2002
Abstract  | Full Text (HTML/ PDF)

Integrated genomic and epigenomic analyses pinpoint biallelic gene inactivation in tumors
Giuseppe  Zardo, Maarit I. Tiirikainen, Chibo Hong, Anjan Misra, Burt G. Feuerstein, Stanislav Volik, Colin C. Collins, Kathleen R. Lamborn, Andrew Bollen, Daniel Pinkel, Donna G. Albertson  & Joseph F.  Costello
Nature Genetics 32, 453-458  2002
Abstract  | Full Text (HTML/ PDF)

Variation in gene expression within and among natural populations
Marjorie F.  Oleksiak, Gary A. Churchill  & Douglas L.  Crawford
Nature Genetics 32, 261-266  2002
Abstract  | Full Text (HTML/ PDF)

The transcriptional program of meiosis and sporulation in fission yeast
Juan Mata, Rachel Lyne, Gavin Burns  & Jürg Bähler
Nature Genetics 32, 143-147  2002
Abstract  | Full Text (HTML/ PDF)

Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait
Daniel P.  Toma, Kevin P. White, Jerry Hirsch  & Ralph J.  Greenspan
Nature Genetics 31, 349-353  2002
Abstract  | Full Text (HTML/ PDF)

Large-scale prediction of Saccharomyces cerevisiae gene function using overlapping transcriptional clusters
Lani F.  Wu, Timothy R. Hughes, Armaity P. Davierwala, Mark D. Robinson, Roland Stoughton  & Steven J.  Altschuler
Nature Genetics 31, 255-265  2002
Abstract  | Full Text (HTML/ PDF)

A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer
Hiromu  Suzuki, Edward Gabrielson, Wei Chen, Ramaswamy Anbazhagan, Manon van Engeland, Matty P. Weijenberg, James G. Herman  & Stephen B.  Baylin
Nature Genetics 31, 141-149  2002
Abstract  | Full Text (HTML/ PDF)

MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia
Scott A.  Armstrong, Jane E. Staunton, Lewis B. Silverman, Rob Pieters, Monique L. den Boer, Mark D. Minden, Stephen E. Sallan, Eric S. Lander, Todd R. Golub  & Stanley J.  Korsmeyer
Nature Genetics 30, 41-47  2001
Abstract  | Full Text (HTML/ PDF)

Assembly of microarrays for genome-wide measurement of DNA copy number
Antoine M.  Snijders, Norma Nowak, Richard Segraves, Stephanie Blackwood, Nils Brown, Jeffrey Conroy, Greg Hamilton, Anna Katherine Hindle, Bing Huey, Karen Kimura, Sindy Law, Ken Myambo, Joel Palmer, Bauke Ylstra, Jingzhu Pearl Yue, Joe W. Gray, Ajay N. Jain, Daniel Pinkel  & Donna G.  Albertson
Nature Genetics 29, 263-264  2001
Full Text (HTML/ PDF)

Transcriptional regulation and function during the human cell cycle
Raymond J.  Cho, Mingxia Huang, Michael J. Campbell, Helin Dong, Lars Steinmetz, Lisa Sapinoso, Garret Hampton, Stephen J. Elledge, Ronald W. Davis  & David J.  Lockhart
Nature Genetics 27, 48-54  2001
Abstract  | Full Text (HTML/ PDF)

Mining the human genome using microarrays of open reading frames
Sharron G.  Penn, David R. Rank, David K. Hanzel  & David L.  Barker
Nature Genetics 26, 315-318  2000
Abstract  | Full Text (HTML/ PDF)

A computational analysis of whole-genome expression data reveals chromosomal domains of gene expression
Barak A.  Cohen, Robi D. Mitra, Jason D. Hughes  & George M.  Church
Nature Genetics 26, 183-186  2000
Abstract  | Full Text (HTML/ PDF)

Nature Medicine

Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators
Yanlin Yu, Javed Khan, Chand Khanna, Lee Helman, Paul S. Meltzer & Glenn Merlino
Nature Medicine 10, 175-181  2004
Abstract  | Full Text (HTML/ PDF)

Molecular determinants of resistance to antiandrogen therapy
Charlie D. Chen, Derek S. Welsbie, Chris Tran, Sung Hee Baek, Randy Chen, Robert Vessella, Michael G Rosenfeld  & Charles L  Sawyers
Nature Medicine 10, 33-39  2004
Abstract  | Full Text (HTML/ PDF)

Predicting hepatitis B viruspositive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learning
Qing-Hai  Ye, Lun-Xiu Qin, Marshonna Forgues, Ping He, Jin Woo Kim, Amy C. Peng, Richard Simon, Yan Li, Ana I. Robles, Yidong Chen, Zeng-Chen Ma, Zhi-Quan Wu, Sheng-Long Ye, Yin-Kun Liu, Zhao-You Tang  & Xin Wei  Wang
Nature Medicine 9, 416-423  2003
Abstract  | Full Text (HTML/ PDF)

HIV-1 Tat reprograms immature dendritic cells to express chemoattractants for activated T cells and macrophages
Elena  Izmailova, Frederic M.N. Bertley, Qian Huang, Norbert Makori, Christopher J. Miller, Richard A. Young  & Anna  Aldovini
Nature Medicine 9, 191-197  2003
Abstract  | Full Text (HTML/ PDF)

Gene-expression profiles predict survival of patients with lung adenocarcinoma
David G.  Beer, Sharon L.R. Kardia, Chiang-Ching Huang, Thomas J. Giordano, Albert M. Levin, David E. Misek, Lin Lin, Guoan Chen, Tarek G. Gharib, Dafydd G. Thomas, Michelle L. Lizyness, Rork Kuick, Satoru Hayasaka, Jeremy M.G. Taylor, Mark D. Iannettoni, Mark B. Orringer  & Samir  Hanash
Nature Medicine 8, 816-824  2002
Abstract  | Full Text (HTML/ PDF)

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
Christopher  Lock, Guy Hermans, Rosetta Pedotti, Andrea Brendolan, Eric Schadt, Hideki Garren, Annette Langer-Gould, Samuel Strober, Barbara Cannella, John Allard, Paul Klonowski, Angela Austin, Nagin Lad, Naftali Kaminski, Stephen J. Galli, Jorge R. Oksenberg, Cedric S. Raine, Renu Heller  & Lawrence  Steinman
Nature Medicine 8, 500-508  2002
Abstract  | Full Text (HTML/ PDF)

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning
Margaret A.  Shipp, Ken N. Ross, Pablo Tamayo, Andrew P. Weng, Jeffery L. Kutok, Ricardo C.T. Aguiar, Michelle Gaasenbeek, Michael Angelo, Michael Reich, Geraldine S. Pinkus, Tane S. Ray, Margaret A. Koval, Kim W. Last, Andrew Norton, T. Andrew Lister, Jill Mesirov, Donna S. Neuberg, Eric S. Lander, Jon C. Aster  & Todd R.  Golub
Nature Medicine 8, 68-74  2002
Abstract  | Full Text (HTML/ PDF)

The EMBO Journal

Genome-wide location of yeast RNA polymerase III transcription machinery
Olivier  Harismendy, Christiane-Gabrielle Gendrel, Pascal Soularue, Xavier Gidrol, André Sentenac, Michel Werner  & Olivier  Lefebvre
The EMBO Journal 22, 4738-4747  2003
Abstract  | Full Text (HTML/ PDF)

Genome-wide analysis of nuclear mRNA export pathways in Drosophila
Andrea  Herold, Luis Teixeira  & Elisa  Izaurralde
The EMBO Journal 22, 2472-2483  2003
Abstract  | Full Text (HTML/ PDF)

EMBO Reports

Monitoring global messenger RNA changes in externally controlled microarray experiments
Jeroen  van de Peppel, Patrick Kemmeren, Harm van Bakel, Marijana Radonjic, Dik van Leenen  & Frank C.P.  Holstege
EMBO reports 4, 387-393  2003
Abstract  | Full Text (HTML/ PDF)

European Journal of Human Genetics

Simple two-color array-based approach for mutation detection
Paolo  Fortina, Kathleen Delgrosso, Taku Sakazume, Rosa Santacroce, Stephane Moutereau, Hung-Ju Su, David Graves, Steven McKenzie  & Saul  Surrey
European Journal of Human Genetics 8, 884-894 
Full Text (HTML/ PDF)

Genes and Immunity

Mining microarray data to identify transcription factors expressed in nave resting but not activated T lymphocytes
C  Argyropoulos, G C Nikiforidis, M Theodoropoulou, P Adamopoulos, S Boubali, T N Georgakopoulos, F Paliogianni, A G Papavassiliou  & A  Mouzaki
Genes and Immunity 5, 16-25  2004
Full Text (HTML/ PDF)

Analysis of gene expression profiles in human systemic lupus erythematosus using oligonucleotide microarray
G-M  Han, S-L Chen, N Shen, S Ye, C-D Bao  & Y-Y  Gu
Genes and Immunity 4, 177-186  2003
Full Text (HTML/ PDF)

Discovery of distinctive gene expression profiles in rheumatoid synovium using cDNA microarray technology: evidence for the existence of multiple pathways of tissue destruction and repair
T C T M  van der Pouw Kraan, F A van Gaalen, T W J Huizinga, E Pieterman, F C Breedveld  & C L  Verweij
Genes and Immunity 4, 187-196  2003
Full Text (HTML/ PDF)

Leukemia

DNA microarrays for comparison of gene expression profiles between diagnosis and relapse in precursor-B acute lymphoblastic leukemia: choice of technique and purification influence the identification of potential diagnostic markers
F J T  Staal, M van der Burg, L F A Wessels, B H Barendregt, M R M Baert, C M M van den Burg, C Van Huffel, A W Langerak, V H J van der Velden, M J T Reinders  & J J M  van Dongen
Leukemia 17, 1324-1332  2003
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Oncogene

Expression profiles of non-small cell lung cancers on cDNA microarrays: Identification of genes for prediction of lymph-node metastasis and sensitivity to anti-cancer drugs
Takefumi  Kikuchi, Yataro Daigo, Toyomasa Katagiri, Tatsuhiko Tsunoda, Koichi Okada, Soji Kakiuchi, Hitoshi Zembutsu, Yoichi Furukawa, Masafumi Kawamura, Koichi Kobayashi, Kohzoh Imai  & Yusuke  Nakamura
Oncogene 22, 2192-2205  2003
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Genome-wide screening for complete genetic loss in prostate cancer by comparative hybridization onto cDNA microarrays
Jeremy  Clark, Sandra Edwards, Andrew Feber, Penny Flohr, Megan John, Ian Giddings, Sue Crossland, Michael R Stratton, Richard Wooster, Colin Campbell  & Colin S  Cooper
Oncogene 22, 1247-1252  2003
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