This library contains links to a number of recently published articles about Kinases in cancer from across the Nature Publishing Group. Click on the article type required to the left or below.
Lung cancer Intragenic ERBB2 kinase mutations in tumours Philip Stephens, Chris Hunter, Graham Bignell, Sarah Edkins, Helen Davies, Jon Teague, Claire Stevens, Sarah O'Meara, Raffaella Smith, Adrian Parker, Andy Barthorpe, Matthew Blow, Lisa Brackenbury, Adam Butler, Oliver Clarke, Jennifer Cole, Ed Dicks, Angus Dike, Anja Drozd, Ken Edwards, Simon Forbes, Rebecca Foster, Kristian Gray, Chris Greenman, Kelly Halliday, Katy Hills, Vivienne Kosmidou, Richard Lugg, Andy Menzies, Janet Perry, Robert Petty, Keiran Raine, Lewis Ratford, Rebecca Shepherd, Alexandra Small, Yvonne Stephens, Calli Tofts, Jennifer Varian, Sofie West, Sara Widaa, Andrew Yates, Francis Brasseur, Colin S. Cooper, Adrienne M. Flanagan, Margaret Knowles, Suet Y. Leung, David N. Louis, Leendert H. J. Looijenga, Bruce Malkowicz, Marco A. Pierotti, Bin Teh, Georgia Chenevix-Trench, Barbara L. Weber, Siu T. Yuen, Grace Harris, Peter Goldstraw, Andrew G. Nicholson, P. Andrew Futreal, Richard Wooster & Michael R. Stratton Nature 431, 525-526 2004 Full Text (HTML/ PDF)
Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB Sirith Douma, Theo van Laar, John Zevenhoven, Ralph Meuwissen, Evert van Garderen & Daniel S. Peeper Nature 430, 1034-1039 2004 Abstract
| Full Text (HTML/ PDF)
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy Hans-Guido Wendel, Elisa de Stanchina, Jordan S. Fridman, Abba Malina, Sagarika Ray, Scott Kogan, Carlos Cordon-Cardo, Jerry Pelletier & Scott W. Lowe Nature 428, 332-337 2004 Abstract
| Full Text (HTML/ PDF)
Bioluminescent imaging of Cdk2 inhibition in vivo Guo-Jun Zhang, Michal Safran, Wenyi Wei, Erik Sorensen, Peter Lassota, Nikolai Zhelev, Donna S Neuberg, Geoffrey Shapiro & William G Kaelin Nature Medicine 10, 643-648 2004 Abstract
| Full Text (HTML/ PDF)
mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways Pradip K Majumder, Phillip G Febbo, Rachel Bikoff, Raanan Berger, Qi Xue, Louis M McMahon, Judith Manola, James Brugarolas, Timothy J McDonnell, Todd R Golub, Massimo Loda, Heidi A Lane & William R Sellers Nature Medicine 10, 594-601 2004 Abstract
| Full Text (HTML/ PDF)
VX-680, a potent and selective small-molecule inhibitor of the Aurora kinases, suppresses tumor growth in vivo Elizabeth A Harrington, David Bebbington, Jeff Moore, Richele K Rasmussen, Abi O Ajose-Adeogun, Tomoko Nakayama, Joanne A Graham, Cecile Demur, Thierry Hercend, Anita Diu-Hercend, Michael Su, Julian M C Golec & Karen M Miller Nature Medicine 10, 262-267 2004 Abstract
| Full Text (HTML/ PDF)
Requirement of Src kinases Lyn, Hck and Fgr for BCR-ABL1-induced B-lymphoblastic leukemia but not chronic myeloid leukemia Yiguo Hu, Yuhua Liu, Shawn Pelletier, Elisabeth Buchdunger, Markus Warmuth, Doriano Fabbro, Michael Hallek, Richard A Van Etten & Shaoguang Li Nature Genetics 36, 453-461 2004 Abstract
| Full Text (HTML/ PDF)
Disease associated mutations at valine 804 in the RET receptor tyrosine kinase confer resistance to selective kinase inhibitors Francesca Carlomagno, Teresa Guida, Suresh Anaganti, Giancarlo Vecchio, Alfredo Fusco, Anderson J Ryan, Marc Billaud & Massimo Santoro Oncogene 23, 6056-6063 2004 Full Text (HTML/ PDF)
Tyrosine kinase inhibitor AG1024 exerts antileukaemic effects on STI571-resistant Bcr-Abl expressing cells and decreases AKT phosphorylation E Deutsch, L Maggiorella, B Wen, M L Bonnet, K Khanfir, V Frascogna, A G Turhan & J Bourhis British Journal of Cancer 91, 1735-1741 2004 Full
Text (HTML/ PDF)
Cyclin-dependent kinase inhibitor Roscovitine induces apoptosis in chronic lymphocytic leukemia cells I N Hahntow, F Schneller, M Oelsner, K Weick, I Ringshausen, F Fend, C Peschel & T Decker Leukemia 18, 747-755 2004 Full Text (HTML/ PDF)
