/* This must be display none in all desktop styles as it is used to monitor mobile css for WT */
#mobile-css-test {
	display: none;
}

body {
	/*color: #55626b;*/
	/*color: #4f5c65;*/
	color: #333;
    line-height: 1.534em;
}

h1, h2, h3, h4, h5, .toggle a, .legend {
	/*color: #597382;*/
	color: #444;
}
a { 
	color: #3877a2;
	text-decoration: none;
	font-weight: bold;
}
a:active {
	outline: 0 none;
}
a:hover {
	color: #000;
	text-decoration: underline;
}

div.content a, div.figure-preview a {
	text-decoration: none;
	font-weight: normal;
	border-bottom: 1px dotted #387782;
}
div.content a:hover, #content ul.box-footer a:hover {
	text-decoration: none;
	border-bottom: 1px solid #000;
}
div.content ul.section-nav a,
div.content ul.figure-nav a,
div.content div.article-tools a,
div.content div.figure-browser a.nav,
#extranav div.content .box-footer a,
div.content a.fig-link,
div.figure-preview p.fig-link a,
div.content p.full-text-link a {
	font-weight: bold;
	border: 0 none;
}

div.content div.figure-content a.fig-link {
	margin-bottom: 1.0em;
	display: block;
}

div.content ul.section-nav a:hover,
div.content ul.figure-nav a:hover,
div.content div.article-tools a:hover,
div.content div.figure-browser a.nav:hover,
div.content a.fig-link:hover,
div.figure-preview p.fig-link a:hover,
#content ul.box-footer a:hover {
	border: 0 none;
}

div.content a.compound-ref {
	font-weight: bold;
}

div.content i + sub,
div.content i + sup {
    margin-left: 0.15em;
}

em, i {
	font-style: italic;
}
h1, h2, h3, h4, h4, strong, b {
	font-weight: bold;
}
cite {
	font-style: normal;
}
sup, sub {
	font-size: 85%;
	line-height: 0;
}
sup {
	vertical-align: super;
}
sub {
	position: relative;
	bottom: -0.6ex;
}
p, h1, h2, h3, h4, h5, ul, ol, dl {
	margin: 0 0 20px;
}
button {
	cursor: hand;
	cursor: pointer;
}
span.mb {
	font-family: "arial unicode ms","lucida grande","lucida sans unicode",sans-serif !important;
	font-size: inherit !important;
	font-weight: inherit !important;
	line-height: inherit !important;
	display: inline !important;
	visibility: visible !important;
	background: transparent none !important;
	padding: 0 !important;
}



/* list styles */
html body ul.bullet, ol.number, ol.ucletter, ol.lcletter, ol.ucroman, ol.lcroman {
	margin: 0 0 20px 3em;
	list-style-position: outside;
}
html body ul.bullet li, ol.number li, ol.ucletter li, ol.lcletter li, ol.ucroman li, ol.lcroman li {
	margin: 10px 0;
	list-style-position: outside;
}

html body ul.bullet, html body ul.bullet li {
	list-style-type: disc;
}
ul.bullet ul.bullet, ul.bullet li ul.bullet li {
	list-style-type: circle;
}
ol.number, ol.number li {
	list-style-type: decimal;
}
ol.ucletter, ol.ucletter li {
	list-style-type: upper-alpha;
}
ol.lcletter, ol.lcletter li {
	list-style-type: lower-alpha;
}
ol.ucroman, ol.ucroman li {
	list-style-type: upper-roman;
}
ol.lcroman, ol.lcroman li {
	list-style-type: lower-roman;
}
dl.norm dd {
	margin-left: 40px;
}


/*basic classes*/
.nature {
	color: #c03;
}
.jobs, .events {
	color: #000;
}
.journal-title, .source-title {
	font-style: italic;
	text-transform: capitalize;
}
.article-type {
	font-weight: bold;
}
.article-type .nfv {
	padding-left: 1em;
	text-transform: none;
}
.scp {
	text-transform: uppercase;
	font-size: 85%;
}
.article-type .journal-title {
	text-transform: uppercase;
}
.divider {
	padding: 0 0.2em;
}
.volume {
	font-weight: bold;
}
.volume span {
	font-weight:normal;
}
.hidden {
	position: absolute;
	left: 0; top: -500px;
	overflow: hidden;
	width: 1px; height: 1px;
}
.additional-data {
	position: absolute;
	left: 0; top: -999em;
	visibility: hidden;
}
.ugc {
	overflow: hidden;
}
.box {
	margin: 0 0 20px; padding: 9px 19px;
	border: 1px solid #e7e7e7;
}

.align-middle {
	vertical-align: middle;
}
.ad {
	line-height: 0 !important;
}



div.no-padding {
	padding: 0;
}
div.box-padding {
	padding: 9px;
}
.left-arrow a {
	padding-left: 12px;
	background: url(http://www.nature.com/view/images/arrow_small_left.gif) no-repeat 0 50%;
}
.up-arrow a {
	padding-left: 12px;
	background: url(http://www.nature.com/view/images/arrow_small_up.gif) no-repeat 0 50%;
}
.right-arrow a {
	padding-right: 12px;
	background: url(http://www.nature.com/view/images/arrow_small_right.gif) no-repeat 100% 50%;
}
.down-arrow a {
	padding-right: 12px;
	background: url(http://www.nature.com/view/images/arrow_small_down.gif) no-repeat 100% 50%;
}
body .scroll-highlight {
	background: #ff9;
}



#header {
	position: relative;
	min-height: 120px;
	clear: both;
	background-repeat: no-repeat;
	background-position: left top;
}
#header h1 {
	position: absolute;
	left: 0;
	text-indent: -9999em;
}
/*
[VIEW-2304]
Adding styles for when the header contains a link back to the journal searched
*/
#header h1.block-anchor {
    position: static;
    top: 0;
}
#header h1.block-anchor a {
    display: block;
    text-indent: -9999em;
    width: 410px;
    height: 120px;
    float: left;
    overflow: hidden;
}



#constrain-header form.search-form {
	padding: 5px 0 0 0;
	float: right;
}
#constrain-header form.search-form label,
#constrain-header form.search-form a {
	font-weight: bold;
}
#constrain-header form.search-form label,
#constrain-header form.search-form a,
#constrain-header form.search-form input.txt,
#constrain-header form.search-form select,
#constrain-header form.search-form button {
	display: block;
	float: left;
	font-size: 85%;
}
body.ie6 #constrain-header form.search-form fieldset {
	padding: 2px 0;
	float: left;
}
#constrain-header form.search-form input.txt,
#constrain-header form.search-form label,
#constrain-header form.search-form select,
#constrain-header form.search-form button {
	margin: 0 5px 0 0; padding: 1px;
}
body.ie6 #constrain-header form.search-form button,
body.ie7 #constrain-header form.search-form button,
body.ie8 #constrain-header form.search-form button {
	margin-top: -1px;
}

/* for when the search box appears inside the main part of the header */
#header form.search-form {
	margin: 0; padding: 5px 5px 5px 10px;
	position: absolute;
	right: 0; bottom: 0;
	background: transparent url(http://www.nature.com/view/images/bg_search.png) no-repeat 0 0;
	color: #fff;
	float: none;
}
#header form.search-form label,
#header form.search-form a {
	color: #fff;
}
body.ie6 #constrain-header form.search-form {
	margin: 0; padding: 5px 0 0 5px;
	min-width: 300px;
}
body.ie6 #header form.search-form a {
	margin-right: 5px;
}





#header div.logon {
	float: right;
	clear: right;
	color: #fff;
	padding: 5px;
}
#header div.logon p {
	text-align: right;
	margin: 0;
}
#header div.logon a {
	color: #fff;
	padding: 0 0 0 18px;
}
#header div.logon a.login,
#header div.logon a.logout:hover {
	background: url(http://www.nature.com/view/images/bg_login.gif) no-repeat 0 50%;
}
#header div.logon a.logout,
#header div.logon a.login:hover {
	background: url(http://www.nature.com/view/images/bg_logout.gif) no-repeat 0 50%;
}
#header .header-tabs {
	bottom: 0px;
	margin: 0;
	padding-left:2px;
	position: absolute;
}
#header .header-tabs li {display: inline;}
#header .header-tabs li a {
	background: #fff;
	border: 1px solid #909597;
	float: left;
	font-size: 93%;
	margin-left: 3px;
	padding: 0.1em 1em;
}
/* An active tab should have {border-bottom: 0;} */
ul.global-nav {
	margin: 0;
	float: left;
}
ul.global-nav li {
	float: left;
	padding: 0 20px 0 0;
}
ul.global-nav li a {
	display: block;
	color: #313131;
	font-size: 85%;
	font-weight: bold;
	padding: 5px 0 5px 15px;
	background: url(http://www.nature.com/view/images/bg_publications_links.gif) no-repeat 0 50%;
}
body ul.global-nav li a:hover {
	color: #f00;
}
ul.global-nav li.home a {
	font-family: garamond,georgia,serif;
	font-size: 108%;
	text-transform: lowercase;
	color: #c00;
	padding: 5px 0 5px 25px;
	background-image: url(http://www.nature.com/view/images/bg_nature_home.gif);
}

#leaderboard {
	position: relative;
	min-height: 92px;
	clear: both;
    z-index:1;
}
#leaderboard-ad {
	position: absolute;
	left: 0; top: 0;
	z-index: 1;
	overflow: visible;
	padding: 0 15px;
	background: transparent url(http://www.nature.com/view/images/bg_leaderboard_ad.gif) no-repeat 0 0;
}

#leaderboard-ad img {
	display: block;
	margin: 0; padding: 0;
}
#leaderboard ul.user-services {
	float: right;
	width: 203px;
	font-size: 85%;
	margin: 0;
}
#leaderboard ul.user-services li {
	margin: 0 0 1px;
	border: 1px solid #a2a2a2;
	border-top-color: #e6e6e6;
	border-left-color: #e6e6e6;
	background: #faf8f9 url(http://www.nature.com/view/images/bg_leaderboard_user_services.gif) repeat-x 0 100%;
}
#leaderboard ul.user-services a {
	display: block;
	padding: 0px 10px 0px 35px;
	background-repeat:no-repeat;
	background-position:10px 50%;
}


#header ul.user-services {
	float: right;
	margin-bottom: -5px;
}
#header ul.user-services li {
	float: left;
}
#header ul.user-services a {
	font-size: 85%;
	color: #fff;
	display: block;
	padding: 0 10px;
	background: url(http://www.nature.com/view/images/bg_register_list.png) no-repeat 0 100%; /* gif for ie6 is added in site styles */
}
#header ul.user-services a:hover {
	background: url(http://www.nature.com/view/images/bg_register_list_hover.png) no-repeat 0 100%;
}



ul.breadcrumbs, ul.prev-next-article {
	margin: 0 0 -5px; padding: 5px 0 0;
	float: left;
}
ul.prev-next-article {
	float: right;
}

#content ul.prev-next-article {
	margin: 0;
	padding: 0;
}
ul.breadcrumbs a, ul.prev-next-article a {
	text-transform: lowercase;
}
ul.breadcrumbs li, ul.prev-next-article li {
	display: inline;
	font-weight: bold;
}
ul.prev-next-article li.prev {
	padding-right: 5px;
}
body.ie6 ul.breadcrumbs, body.ie6 ul.prev-next-article {
	position: relative;
}




/* highlighting tool */
html.js-enabled #highlighting-tool {
	display: none;
}
#highlighting-tool {
	margin: 20px 0 0;
}
#highlighting-tool h2.highlighting-heading {
	margin: 0;
}
#highlighting-tool form {
	margin: 0;
}
#highlighting-tool label {
	display: block;
	margin: 0 20px 0 3px; padding: 1px 10px;
	float: left;
	cursor: auto;
}
#highlighting-tool input.checkbox {
	display: block;
	float: left;
	margin-top: 5px;
}
#highlighting-tool fieldset {
	margin: 0; padding: 0;
	border: 0;
}
#highlighting-tool button {
	float: right;
}
.js-enabled #highlighting-tool button {
	display: none;
}


.highlight-compound,
.highlight-chemical {
	background: #fbd6a1 url(http://www.nature.com/view/images/bg_highlight1.gif) repeat-x 0 0;
	cursor: help;
	font-weight: inherit !important;
}
.highlight-geneprot,
.highlight-protein {
	background: #cde5b1 url(http://www.nature.com/view/images/bg_highlight2.gif) repeat-x 0 0;
	cursor: help;
	font-weight: inherit !important;
}
.is-staging .highlight-entity-missing {
	background: #c00;
}
body.ie6 ul.compound-props span.highlight-compound,
body.ie6 ul.compound-props span.highlight-chemical,
body.ie6 ul.compound-props span.highlight-geneprot,
body.ie6 ul.compound-props span.highlight-protein,
body.ie7 ul.compound-props span.highlight-compound,
body.ie7 ul.compound-props span.highlight-chemical,
body.ie7 ul.compound-props span.highlight-geneprot,
body.ie7 ul.compound-props span.highlight-protein {
	font-weight: normal !important;
}

/* all except the .annotation rules can be deleted once macros have been reloaded  */
h1 .highlight-compound, 
h2 .highlight-compound, 
h3 .highlight-compound, 
h4 .highlight-compound, 
b .highlight-compound, 
span.legend .highlight-compound,
#acknowledgments .highlight-compound,
#author-information .highlight-compound,
#author-contributions .highlight-compound,
div.figures-at-a-glance .highlight-compound,
.section-nav .highlight-compound,
h1 .highlight-chemical, 
h2 .highlight-chemical, 
h3 .highlight-chemical, 
h4 .highlight-chemical, 
b .highlight-chemical, 
span.legend .highlight-chemical, 
#acknowledgments .highlight-chemical,
#author-information .highlight-chemical,
#author-contributions .highlight-chemical,
div.figures-at-a-glance .highlight-chemical,
.section-nav .highlight-chemical,
h1 .highlight-geneprot, 
h2 .highlight-geneprot, 
h3 .highlight-geneprot, 
h4 .highlight-geneprot, 
b .highlight-geneprot, 
span.legend .highlight-geneprot,
#acknowledgments .highlight-geneprot,
#author-information .highlight-geneprot,
#author-contributions .highlight-geneprot,
div.figures-at-a-glance .highlight-geneprot,
.section-nav .highlight-geneprot,
h1 .highlight-protein, 
h2 .highlight-protein, 
h3 .highlight-protein, 
h4 .highlight-protein, 
b .highlight-protein, 
span.legend .highlight-protein,
#acknowledgments .highlight-protein,
#author-information .highlight-protein,
#author-contributions .highlight-protein,
div.figures-at-a-glance .highlight-protein,
.section-nav .highlight-protein,
h1 .highlight-entity-missing, 
h2 .highlight-entity-missing, 
h3 .highlight-entity-missing, 
h4 .highlight-entity-missing, 
b .highlight-entity-missing, 
span.legend .highlight-entity-missing,
#acknowledgments .highlight-entity-missing,
#author-information .highlight-entity-missing,
#author-contributions .highlight-entity-missing,
div.figures-at-a-glance .highlight-entity-missing,
.section-nav .highlight-entity-missing,
h1 .annotation, 
h2 .annotation, 
h3 .annotation, 
h4 .annotation, 
b .annotation, 
span.legend .annotation,
#acknowledgments .annotation,
#author-information .annotation,
#author-contributions .annotation,
div.figures-at-a-glance .annotation,
.section-nav .annotation {
	background: transparent none !important;
	cursor: auto !important;
}

/*
.highlight3 {
	background: #f3c8d2 url(http://www.nature.com/aotf/images/bg_highlight3.gif) repeat-x 0 0;
}
.highlight4 {
	background: #bfd5ea url(http://www.nature.com/aotf/images/bg_highlight4.gif) repeat-x 0 0;
}
.highlight5 {
	background: #f7e4a0 url(http://www.nature.com/aotf/images/bg_highlight5.gif) repeat-x 0 0;
}
*/
span.highlight-off {
	background: transparent none !important;
}
div.popup p.gene-name {
	margin: 0;
}

h1.article-heading, h1.main-heading {
	color: #000;
	font-weight: normal;
	font-size: 197%;
	letter-spacing: -0.5px;
	line-height: 1.173;
	color: #222;
	margin: 0 0 20px;
}
h2.article-subheading {
	color: #000;
	font-weight: normal;
	font-size: 157%;
	letter-spacing: -0.5px;
	line-height: 1.173;
	color: #222;
	margin: -10px 0 20px;
}
h2.article-subheading span {
	display: block;
}
body.ie6 h1.article-heading {
	padding-top: 20px;
}

h1.article-heading span.multiple-title {
	display: block;
}
h1.article-heading span.multiple-title + span.multiple-title {
	padding-top: 0.83em;
}

h1.main-heading {
	margin: 0;
}
h2.sub-heading {
	font-size: 116%;
	margin: 10px 0 2px;
}
p.article-type {
	margin: 0 0 20px;
	color: #a1aeb7;
	text-transform: uppercase;
	letter-spacing: -0.5px;
	float: left;
}

a.enhanced {
	color:#F5821F;
}

div.standfirst, div.first-paragraph, 
div.content div.standfirst a, div.content div.first-paragraph a {
	font-weight: bold;
}

div.standfirst b, div.first-paragraph b {
	font-weight:normal;
}


/* display of the authors at the top of the article */
ul.citation-authors {
	font-weight: bold;
}

ul.authors {
	margin: 0 0 10px 0;
}
ul.authors li {
	display: inline;
}
ul.authors li span.fn sup {
	display: inline;
}

#author-extra-details li {
	margin: 0 0 10px;
}
.js-enabled ul.authors sup, .js-enabled #author-extra-details {
	display: none;
}
.js-enabled #author-extra-details.show-author {
	display: block;
}
div.author-search {
	font-size: 92%;
}
div.author-search li {
	float: left;
	margin: 0; padding: 0 4px 3px 7px;
	background: url(http://www.nature.com/view/images/bullet_small.gif) no-repeat 0 50%;
	white-space: nowrap;
}
div.author-search li.first {
	background-image: none;
	padding-left: 0;
}
div.author-search a {
	font-weight: bold;
	text-decoration: none;
}
.author-details {
	clear: both;
}
.author-details h3, .author-details h4, .author-details p.email {
	margin: 0;
}
div.popup ul.author-affiliations, 
div.popup ul.corresponding-authors {
	margin: 0;
	padding: 8px 0;
}
div.popup ul.author-img-wrapper {
	padding-left: 70px;
	background-repeat:no-repeat;
	background-position: 0 10px;
	min-height: 70px;
}
div.popup ul.author-affiliations li,
div.popup ul.corresponding-authors li {
	margin: 2px 0;
}
.popup p {
	margin: 0 0 8px;
}

#author-links {
	margin: 0 0 20px;
}
#author-links li {
	float: left;
	padding: 0 0.5em;
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat scroll 0 0.6ex;
}
#author-links li.first {
	padding-left: 0;
	background-image: none;
}

/* the these authors contributed equally section in the author popup */
div.popup ul.author-affiliations h3 {
	margin: 10px 0 0;
}
div.popup ul.affiliation-authors, div.popup ul.affiliation-authors li {
	display: inline;
}

div.related-content ul.authors {
	margin: 0 0 -2px;
}

li.author-toggle {
	white-space: nowrap;
}
li.authors-toggle a {
	padding-left:15px;
	background:#fff url(http://www.nature.com/view/images/contract_small.gif) no-repeat 0 50%;
	margin-left: 10px;
	white-space: nowrap;
}
li.authors-toggle a.collapsed {
	background-image:url(http://www.nature.com/view/images/expand_small.gif);
}
body.ie6 li.authors-toggle a {
	display: inline-block;
}


dl.citation, dl.citation-dates {
	margin: 0;
}
/*
VIEW-2313
No pagination on the inside this article pages so 
need to nudge the content down on this element
*/
div.inside-article dl.citation {
    margin-bottom: 20px;
}
dl.citation dt {
	display: none;
}
dl.citation dd {
	padding: 0 3px 0 0;
	display: inline;
}
dl.citation dd.doi {
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 0 0.4ex;
	padding-left: 10px;
	margin-left: 4px;
}
dl.citation dt.seq {
	display: inline;
}
dl.dates dt {
	padding: 0 3px 0 0;
	display: inline;
}
dl.dates dt.accepted,
dl.dates dt.published-online,
dl.dates dt.corrected-online,
dl.dates dt.first-decision,
dl.dates dt.revised {
	padding-left: 8px;
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 0 0.4ex;
}
dl.dates dt.first {
	padding-left: 0;
	background-image: none !important;
	/* important added as CSS builder adds the above rule with
	   background image below this rule, giving it higher priority */
}

/*
dl.meta dd.volume, dl.meta.dates dd:not(:last-of-type) {
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 100% 0.4ex;
	padding-right: 10px;
	margin-right: 6px;
}
*/



h1.section-heading {
	margin: 18px 0 0; padding: 2px 0;
	font-size: 116%;
	letter-spacing: -0.5px;
}
div.content h2 {
	color: #111;
	margin: 0;
	/*margin: 20px 0 -17px;*/
}
div.section {
	clear: both;
}
div.section div.content {
	border-top: 1px solid #e7e7e7;
	zoom: 1;
}
div.no-nav div.content, div.no-title div.content {
	padding-top: 20px;
}
div.second div.content {
	padding-top: 0;
}
div.no-title div.content {
	border-top: 1px solid #fff; /* prevent margin collapse */
}
div.collapsed div.article-footer {
	margin-top:20px;
}
div.article-footer a {
	font-weight:normal;
}
html.js-enabled div.collapsed .content {
	display: none;
}
/*
[VIEW 2135]
Need to flash a class to apply display block to not ruin additional class styling
with inline styles of .css("display","block")
*/
html.js-enabled div.collapsed .calculateHeights {
	display: block;
}
html.js-enabled .toggle a {
	padding: 0 0 0 23px;
	text-decoration: none;
}
html.js-enabled body.ie6 .toggle a,
html.js-enabled body.ie7 .toggle a {
	position: relative;
}
html.js-enabled div.expanded .toggle a {
	background: url(http://www.nature.com/view/images/collapse.gif) no-repeat 0 50%;
}
html.js-enabled div.collapsed .toggle a {
	background: url(http://www.nature.com/view/images/expand.gif) no-repeat 0 50%;
}

ul.section-nav {
	font-size: 85%;
	color: #a2a7ab;
	margin: 0 0 0 -4px; padding: 5px 0 14px;
}
ul.section-nav li {
	display: inline;
	padding: 0 7px 0 4px;
	background: url(http://www.nature.com/view/images/bullet_small.gif) no-repeat 100% 50%;
	white-space: nowrap;
}
body.ie6 ul.section-nav li,
body.ie7 ul.section-nav li {
	float: left;
}
ul.section-nav li.last {
	background-image: none;
}


div.article-tools {
	float: right;
	margin: 0 0 20px 10px;
}
div.article-tools h2, div.article-tools h3 {
	margin: 0;
}
div.article-tools ul {
	margin: 0; padding: 10px 5px 5px;
	font-size: 85%;
}
div.article-tools ul ul {
	padding: 0;
	font-size: 100%;
}
div.article-tools li {
	margin: 0; padding: 0;
}
div.article-tools a {
	text-transform: lowercase;
}
body.ie6 div.article-tools a {
	width: 100px;
}
div.article-tools li a, ul.bookmarking a, p.download-refs a, div.download-popup li a {
	display: block;
	padding: 0 0 5px 30px;
	background-repeat: no-repeat;
	background-position: 0 0;
}
#content p.download-refs {
	margin-top: 0;
}
#content p.download-refs a {
	padding: 0 0 5px 40px;
	background-repeat: no-repeat;
	background-position: 11px 0;
	border: 0 none;
}
div.article-tools li.print {
	display: none;
}
html.js-enabled div.article-tools li.print {
	display: block;
}
div.article-tools li.japanese a {
	background-image: url(http://www.nature.com/view/images/icon_japan.gif);
}
div.article-tools li.english a {
	background-image: url(http://www.nature.com/view/images/icon_english.gif);
	background-position: 1px 4px;
}
div.article-tools li.print a {
	background-image: url(http://www.nature.com/view/images/icon_print.gif);
}
div.article-tools li.sendtofriend a {
	background-image: url(http://www.nature.com/view/images/icon_email.gif);
}
div.article-tools li.download-pdf a,
div.download-popup li.downloading-pdf a,
div.article-tools li.downloading-pdf a  {
	background-image: url(http://www.nature.com/view/images/icon_download_pdf.gif);
}
div.download-popup li.readcube a {
	background-image: url(http://www.nature.com/view/images/ReadCubeIcon.png);
}	
div.article-tools li.download-citation a, 
p.download-refs a {
	background-image: url(http://www.nature.com/view/images/icon_download_citation.gif);
}
div.article-tools li.order-reprints a,
div.article-tools li.rights a,
div.article-tools li.full-text a {
	background-image: url(http://www.nature.com/view/images/icon_order_reprints.gif);
}
div.article-tools h3 {
	padding: 0 0 10px;
}
ul.bookmarking li.delicious a {
	background-image: url(http://www.nature.com/view/images/icon_delicious.gif);
}
ul.bookmarking li.digg a {
	background-image: url(http://www.nature.com/view/images/icon_digg.gif);
}
ul.bookmarking li.facebook a {
	background-image: url(http://www.nature.com/view/images/icon_facebook.gif);
}
ul.bookmarking li.connotea a {
	background-image: url(http://www.nature.com/view/images/icon_connotea.gif);
}
ul.bookmarking li.twitter a {
	background-image: url(http://www.nature.com/view/images/icon_twitter.gif);
}
ul.bookmarking li.citeulike a {
	background-image: url(http://www.nature.com/view/images/icon_citeulike.gif);
}
html.js-enabled div.article-tools h3 {
	font-weight: normal;
	padding: 0;
}
html.js-enabled div.article-tools h3 a {
	background-image: url(http://www.nature.com/view/images/icon_share.gif);
}
html.js-enabled div.article-tools h3#toggle-download-links a {
	background-image: url(http://www.nature.com/view/images/download_popover.gif);
}
html.js-enabled div.article-tools ul.downloading,
html.js-enabled div.article-tools ul.bookmarking,
html.js-enabled div.document-delivery {
	display: none;
}
div.download-popup,
div.bookmarking-popup,
div.delivery-popup {
	position: absolute;
	z-index: 3;
	margin: 0 0 0 -7px; padding: 0 0 5px;
	width: 260px !important;
}
div.delivery-popup{
	width: 360px !important;
}

div.bookmarking-popup li {
	width: 120px;
	float: left;
}
div.download-popup li {
	float: left;
	width: 100%;
}
div.delivery-popup li{
	padding:0.5em 1em;
}
div.download-popup .title-bar,
div.bookmarking-popup .title-bar,
div.delivery-popup .title-bar {
	padding: 3px 5px;
	background: #b3b8be url(http://www.nature.com/view/images/bg_dark_grad.gif) repeat-x 0 0;
}
div.download-popup .title-bar h2,
div.bookmarking-popup .title-bar h2,
div.delivery-popup .title-bar h2 {
	color: #fff;
}
div.download-popup .popup-content,
div.bookmarking-popup .popup-content,
div.delivery-popup .popup-content {
	padding: 10px;
}
div.download-popup a,
div.bookmarking-popup a {
	font-size: 85%;
}
div.download-popup .downloading-pdf a {
	line-height: 1.2em;
	padding: 0 0 10px 30px;
	
}
div.download-popup .downloading-pdf a span {
	font-size: 90%;
	display: block;
	color: #565656;
}
div.download-popup a:hover,
div.bookmarking-popup a:hover {
	text-decoration: none;
}
/* this would have been a nice place to use display: compact if anything other than opera had something that even vaguely resembled support for it ... */
div.article-keywords {
	padding-left: 8em;
}
div.article-keywords h2, div.article-keywords ul {
	float: left;
}
div.article-keywords h2 {
	margin: 0 0 0 -8em;
}
body.ie6 div.article-keywords h2 {
	margin-left: -4em;
}
div.keywords {
	padding-bottom: 20px;
}
div.keywords h4, div.keywords p {
	display: inline;
	margin: 0;
}
/*
[VIEW-2161]
Article keywords inside of the pseudo-abstract shouldn't have the -ve margin
*/
#pseudo-abstract .article-keywords {
	padding-left: 0;
}
#pseudo-abstract .article-keywords h2 {
	margin-left: 0;
}

body.ie6 div.article-keywords ul, body.ie7 div.article-keywords ul {
	margin: -5px 0 15px;
	width: 100%;
}
body.ie6 div.article-keywords li, body.ie7 div.article-keywords li {
	display: inline;
	padding: 5px 10px 5px 5px;
	background: #f6f6f6 url(http://www.nature.com/view/images/bullet_small.gif) no-repeat 100% 50%;
}


div.article-keywords ul {
	margin: -5px 0 15px;
}
div.article-keywords li {
	float: left;
	padding: 5px 10px 5px 5px;
	background: #f6f6f6 url(http://www.nature.com/view/images/bullet_small.gif) no-repeat 100% 50%;
}


div.article-keywords li.last {
	padding-right: 5px;
	background-image: none;
}

/* VIEW-3105 Article Notes */
div.article-notes {
	margin-top: 20px;
}

p.correspondence, ul.correspondence, ul.correspondence li {
	display: inline;
}
ol.affiliations {
	margin: 0 0 10px;
}
ol.affiliations li {
	margin: 0 0 10px;
}
ol.affiliations h3, ol.affiliations ul li {
	display: inline;
}


#corresponding-authors h2 {
	margin-bottom: 3px;
}
#corresponding-authors {
	margin-bottom: 20px;
}



cite.book {
	font-style: italic;
}
ol.references {
	list-style: decimal;
	padding: 0 0 10px 40px;
}
ol.references li {
	list-style: decimal;
	margin: 0 0 10px;
}
ol.references li li {
	list-style: none;
	margin: 10px 0;
	padding: 0 3px;
	display: inline;
}
ol.alpha, ol.alpha li {
	list-style: none outside none;
}

ol.references ul {
	margin: 0;
	display: block;
	background: #fff;
}
ol.references ul li {
	float: right;
}
ol.references ul.context li {
	display: block;
	float: none;
}
ol.references li.show-context-item {
	float: left;
}
#content ol.references a.ref-return {
	padding: 0 15px 0 10px;
	background: url(http://www.nature.com/view/images/arrow_small_up.gif) no-repeat 100% 50%;
	border-bottom: 0 none;
	font-weight: bold;
}


#content ol.references li.show-context-item a {
	display: block;
	padding: 0 0 0 15px;
	background: url(http://www.nature.com/view/images/expand_small.gif) no-repeat 0 50%;
	border-bottom: 0 none;
}
#content ol.references li.show-context-item a.collapse {
	background: url(http://www.nature.com/view/images/contract_small.gif) no-repeat 0 50%;
}
ol.references ul.context {
	margin: 0 0 10px -22px;
	padding: 0 10px;
	border-left: 10px solid #e7e7e7;
	border-top: 1px solid #fff;
	border-bottom: 1px solid #fff;
	text-align: left;
}
ol.references ul.context ul.section-nav li {
	display: inline;
	padding: 0 7px 0 4px;
}
ol.references div.cit-note {
	margin-left: -40px;
}
ol.references h2.cit-head {
	margin: 0 0 10px -40px;
}



#supplementary-information h2 {
	margin: 0 0 0 -5px; padding: 10px 0 0 25px;
	background: url(http://www.nature.com/view/images/icon_download_compressed.gif) no-repeat 0 10px;
}
#supplementary-information ol {
	list-style: decimal;
	padding: 10px 0 0 20px;
	margin: -17px 0 0 0;
}

body.ie6 #supplementary-information h2 {
	margin: 0; padding: 10px 0 0 20px;
	zoom: 1;
}
body.ie6 #supplementary-information ol {
	margin: 0 0 0 -10px;
	padding: 10px 0 10px 10px;
	zoom: 1;
}
body.ie7 #supplementary-information ol {
	margin: -10px 0 0;
	padding: 10px 0 10px 25px;
	zoom: 1;
}
body.ie6 #supplementary-information ol li {
	padding: 0; margin: 0 0 0 20px;
	vertical-align: top;
}
body.ie6 #supplementary-information ol li dl {
	margin-top: -1.2em;
}
body.ie7 #supplementary-information ol li dl {
	margin-top: -1.3em;
}

#supplementary-information h2.pdf {
	background-image: url(http://www.nature.com/view/images/icon_download_pdf_color.gif);
}
#supplementary-information h2.image {
	background-image: url(http://www.nature.com/view/images/icon_download_bitmap.gif);
}
#supplementary-information h2.html,
#supplementary-information h2.xml {
	background-image: url(http://www.nature.com/view/images/icon_download_markup_language.gif);
}
#supplementary-information h2.svg {
	background-image: url(http://www.nature.com/view/images/icon_download_svg.gif);
}
#supplementary-information h2.excel {
	background-image: url(http://www.nature.com/view/images/icon_download_excel.gif);
}
#supplementary-information h2.word,
#supplementary-information h2.wordperfect {
	background-image: url(http://www.nature.com/view/images/icon_download_word.gif);
}
#supplementary-information h2.movies,
#supplementary-information h2.video {
	background-image: url(http://www.nature.com/view/images/icon_download_movie.gif);
}
#supplementary-information h2.audio {
	background-image: url(http://www.nature.com/view/images/icon_download_audio.gif);
}
#supplementary-information h2.powerpoint {
	background-image: url(http://www.nature.com/view/images/icon_download_powerpoint.gif);
}
#supplementary-information h2.postscript {
	background-image: url(http://www.nature.com/view/images/icon_download_postscript.gif);
}
#supplementary-information ol li {
	margin: 10px 0;
	list-style: decimal;
}
#supplementary-information dd p {
	margin: 0 0 10px;
}


#accessions h2 {
	margin-bottom: 0;
}
#accessions h3 {
	clear: both;
	font-weight: normal;
	margin: 0 0 10px;
}
div.accessions {
	float: left;
	margin: 0 20px 0 0;
}
ul.accessions {
	float: left;
	margin: 0 20px 0 0;
}
ul.accessions a {
	display: block;
}
div.content ul.accessions a,
div.content ul.accessions a:hover {
	border-bottom: 0;
}

#accessions div.primary + div.secondary {
	margin-top: 10px;
}

ul.pdb a {
	padding-left: 25px;
	background: url(http://www.nature.com/view/images/icon_pdb.gif) no-repeat 0 50%;
}
ul.view-3d a {
	padding-left: 25px;
	background: url(http://www.nature.com/view/images/icon_3dview.gif) no-repeat 0 50%;
}

/* comments */
#comments h2 {
	color: #c00;
}
#comments p.view-all {
	text-align: right;
}
#comments p.view-all a {
	font-weight: bold;
	text-decoration: none;
	border-bottom: 0 none;
}
p.comment-rss a {
	padding-left: 20px;
	background: url(http://www.nature.com/view/images/icon_newsfeeds.gif) no-repeat 0 0;
	font-weight: bold;
	border-bottom: 0 none;
}
p.comment-rss a:hover {
	border-bottom: 0 none;
}

ol.comments ul, ol.comments ol {
	list-style-position: inside;
	margin: 20px 0; padding: 0 0 0 25px;
	clear: both;
}

ol.comments ul, ol.comments ul li {
	list-style: disc;
}
ol.comments ol, ol.comments ol li { 
	list-style: decimal;
}

ol.comments li.box {
	zoom: 1;
	background: #fff url(http://www.nature.com/view/images/bg_comment_grad.gif) repeat-x 0 0;
}
ol.comments dt {
	float: left;
	padding-right: 0.2em;
}
ol.comments dt.hide {
	position:absolute;
	left:-5000px;
	top:-5000px;
}
#comments ol.comments dd > *:first-child {
	margin-top: 0;
}
#comments ol.comments p.datetime {
	margin: 0;
	padding: 5px 5px 5px 30px;
	background: url(http://www.nature.com/view/images/icon_comment.gif) no-repeat 0 50%;
	position: relative;
	float: left;
}
/*
a.comment-id {
	float: right;
}
*/
#comments ol.comments p.moderation {
	/*margin: -10px 0 0 0;
	padding: 0 5px 5px 30px;
	clear: both;*/
	margin: 0; padding: 5px;
	float: right;
}     


#comments #recaptcha_table {
	margin-top: 10px;
}

html.js-enabled #comments ol.comments p.moderation {
	position: absolute;
	left: -999em;
}

ol.comments dl {
	margin: 0;
	padding-left: 30px;
	clear: both;
}
ol.comments dt {
	font-weight: bold;
}
#comments p.comment-notice {
	margin: 5px 0;
}

#comment-form {
	margin: 0 0 18px 0;
}

#comment-form textarea {
	width: 100%;
	height: 100px;
	margin: 5px 0; padding: 0;
}

#comment-form textarea:focus {
	border-color: #999;
}
#comment-form .submit {
	background: #fff url(http://www.nature.com/view/images/bg_button.gif) repeat-x 0 100%;
	border: 1px solid #e7e7e7;
	margin: 0; padding: 2px 15px;
	float: right;
	overflow: visible;
	cursor: pointer;
	color: #58626b;
}
#comment-form .submit:hover {
	color: #000;
	border: 1px solid #999;
}
#comment-form #comment-preview-button {
	margin: 0 5px 0 0;
}
html.js-enabled #comment-preview-button {
	display: none;
}

span.comment-agreed {
	display: block;
	float: left;
}

#comment-help h3 {
	margin-bottom: 0;
}
#comment-help li {
	margin: 10px 0;
}
html.js-enabled #comment-help h3 a {
	font-weight: bold;
	display: block;
	padding: 0 0 0 15px;
	background: url(http://www.nature.com/view/images/expand_small.gif) no-repeat 0 4px;
	border-bottom: 0 none;
	color: #111;
}
html.js-enabled #comment-help h3 a.collapse {
	background: url(http://www.nature.com/view/images/contract_small.gif) no-repeat 0 4px;
}
html.js-enabled #comment-help ul {
	display: none;
}


.comment-status {
	padding: 10px; margin: 0 0 20px;
	border: 1px solid #fc0;
	background: #ffefb0;
}
.comment-error {
	padding: 10px;
	border: 1px solid #c00;
	background: #fac7c7;
}
.comment-status h1, .comment-status ul {
	margin: 0;
}
.comment-error h1 {
	color: #c00;
	margin: 0;
}
form .comment-error {
	margin-bottom: 10px;
}







dl.corrections {
	margin: 20px 0 0;
}
dl.corrections dt {
	font-weight: bold;
	float: left;
	padding: 0 0.3em 0 0;
}
dl.corrections dd {
	margin: 20px 0;
}


/* Q and A page */
dt.question {
	font-weight: bold;
}

div.illustration {
	margin: 0; padding: 10px;
	width: auto;
}
div.illustration-left {
	padding: 0 10px 10px 0;
	float: left;
	clear: left;
}
div.illustration-right {
	padding: 10px 0 10px 10px;
	float: right;
	clear: right;
}
/*[VIEW-3072]*/
div div.fullWidthIllustration { margin:0 0 15px; padding:0; }
div div.fullWidthIllustration div.box { padding:13px; }
div div.fullWidthIllustration div.box p.credit { padding:0; margin-bottom:0; }

/*
[VIEW 1791]
IE7 needs the same treatment as both IE6 and 7 treat the floats incorrectly
*/
body.ie6 div.illustration-right,
body.ie7 div.illustration-right {
	clear: none;
	padding-top:0;
}
div.fig-box div.illustration-center {
	padding:0;
}
div.illustration-center {
	clear:both;
}
div.fig-box div.illustration .box {
	border:0;
	background:none;
}
div.fig-box div.description {
	background:none;
}
div.content div.illustration-center div {
	margin: 0 auto;
}
div.illustration div {
	background: #f5f6f7;
}
div.illustration div.box {
	margin: 0; padding: 0;
}
div.illustration img {
	display: block;
}
div.illustration div.description p {
	color:#666;
	font-size: 85%;
	line-height: 1.5em;
	margin: 10px 0;
	padding: 0 10px;
}
div.illustration div.description .glyph {
	display: inline;
}
div.illustration p.credit {
	color:#909090;
	font-size: 75%;
	font-style: italic;
	line-height: 1.4em;
	text-align:right;
	margin: 5px 0 5px 0;
	padding: 0 10px;
}

/* book reviews */
div.additional-review {
	margin: 20px 0;
}
#content div.additional-review div.content {
	border-top: 0 none;
}
div.additional-review div.content h2 {
	margin: 10px 0 0;
}
div.book-review {
	margin: 0 0 -1px;
	padding-bottom: 1px;
}
body.ie6 div.primary-review div.illustration {
	padding: 0 10px 0 0;
}
/* clearing */
div.additional-review:after {
     visibility: hidden;
     display: block;
     font-size: 0;
     content: ' ';
     clear: both;
     height: 0;
 }
div.additional-review {
	display: inline-block;
}
/* start commented backslash hack \*/
body.ie6 div.additional-review {
	height: 1%;
}
div.additional-review {
	display: block;
}
/* close commented backslash hack */



.bookshelf {
	font-weight: normal;
	color: #c00;
	margin: 10px 0 0;
}
.review-title {
	margin: 0;
}
p.isbn {
	margin:0;
}
p.review-meta {
	margin:0 0 20px 0;
}
p.buy-this {
	font-weight: bold;
	margin: 5px 0 20px 0; padding: 0;
}
p.buy-this span {
	padding: 0 0.5em;
}
p.buy-this a,
p.buy-this a:hover {
	border: 0 none;
	font-weight: bold;
}


div.side-note,
div.pull-quote {
	width: 30%;
	float: right;
	clear: right;
	margin: 0 0 10px 10px; padding: 10px 20px 10px 10px;
	border: 1px solid #e7e7e7;
	background: #f6f6f8 url(http://www.nature.com/view/images/bg_pullquote.gif) no-repeat 100% 0;
}
div.side-note {
	background: #f6f6f8 none;
}
body.ie6 div.side-note,
body.ie6 div.pull-quote {
	clear: none;
}
div.side-note blockquote p,
div.pull-quote blockquote p {
	margin: 0;
	font-weight: bold;
}
div.pull-quote p.stated-by {
	text-align: right;
	margin: 5px -10px 0 0;
	font-size: 85%;
	font-style: italic;
}




span.legend {
	font-weight: bold;
}
h2.sub-heading span.from {
	display: block;
}

p.back {
	float: right;
	border: 1px solid #e7e7e7;
	margin: 10px 0; padding: 5px;
	clear: right;
}
p.back a {
	font-weight: normal;
}

div.related-index-box {
	clear: both;
	margin: 0;
}

div.figure-related, div.table-related, div.compound-related, div.scheme-related, div.box-related {
	margin-top: 20px;
}
div.box-related div.figure-content > *:first-child {
	margin-top: 0;
}

div.box-related div.figure-content {
	padding-top: 1px;
	padding-bottom: 1px;
}
div.box-related div.illustration {
	padding: 0;
	float: none;
	clear: both;
}
div.box-related div.illustration div.box {
	border: 0 none;
}
div.box-related li.index {
	visibility: hidden; /* needed to expaned the figure nav under the box since there is no index link */
}

div.table-related, div.table-related div.figure-content, div.inline-table div.figure-content {
	padding: 0;
}
div.compound-related div.figure-content {
	overflow-x:auto;
	position:relative
}
body.ie6 div.compound-related div.figure-content {
	width:98.8%; /* ie6 needs a width for overflow to work, taking border/padding into account */
}
div.related-content div.figure-content div.figure-img-wrapper {
	width: 100%;
	overflow-x: auto;
	margin-bottom: 1em;
}

body.ie7 div.related-content div.figure-content div.figure-img-wrapper,
body.ie7 div.compound-related div.figure-content {
	overflow-y: hidden;
}
/* add space to make room for the scrollbar */
body.ie6 div.related-content div.figure-content div.figure-img-wrapper img,
body.ie7 div.related-content div.figure-content div.figure-img-wrapper img {
	padding: 0 0 25px;
}
div.related-content div.figure-content {
	padding-left: 5px;
	padding-right: 5px;
}
div.related-content div.figure-content div.description {
	margin-left: 5px;
	margin-right: 5px;
}

div.reviewInfo {
	margin-top: 20px;
}
div.reviewInfo h4 {
	margin-bottom: 10px;
}

div.table-wrapper {
	width: 100%;
	overflow-x: auto;
	position: relative; /* fixes issues with sub/sup inside table in IE 6/7 */
}
table.data {
	border-collapse: collapse;
	min-width: 100%;
}
body.ie6 table.data {
	margin-left: -1px;
}
table.data th, table.data td {
	padding: 5px;
	text-align: left;
}
table.data tr {
	background: #f6f6f6;
}
table.data tr.odd, table.data tfoot tr {
	background: #fff;
}
table.data tfoot p {
	margin: 10px 0;
}
table.data tbody td, table.data thead th {
	border-left: 1px solid #ccc;
}
table.data thead th {
	font-weight: bold;
	border-bottom: 1px solid #ccc;
}
table.data td.rowsep {
	border-bottom: 1px solid #ccc;
}
table.data tbody td:first-child, table.data thead th:first-child {
	border-left: 0 none;
}

table.data img.chemimg, 
img.chemimg-box {
	display: block;
	margin: 0 auto 20px auto;
	float: none;
}
img.chemimg-box {
	border: 1px solid #e7e7e7;
	padding: 10px;
}


div.jmol {
	width: 500px;
	float: left
}
div.jmol-instructions {
	float: right;
	width: 430px;
}
div.jmol-instructions h2 {
	margin-top: 10px;
}
p.all-compounds {
	float: left;
}
ul.view-compound {
	margin: 20px 0;
	clear: both;
}

ul.compound-props {
	margin: 20px 0;
}
ul.compound-props span {
	font-weight: bold;
}
div.jmol-instructions dt {
	float: left;
	padding-right: 0.3em;
	font-weight: bold;
}
ul.compound-props li.inchi,
ul.compound-props li.smiles {
	/*
	[VIEW-2892]
	remove white-space:nowrap
	relpace with word-wrap:break-word
	*/
	word-wrap: break-word;
}
ul.compound-props ul.compound-data {
	display: inline;
	padding-left: 0.3em;
}
ul.compound-props ul.compound-data li {
	display: inline;
	padding-right: 0.3em;
}
ul.compound-props li, div.jmol-instructions dd {
	margin-bottom: 10px;
}

/*
[VIEW-2366]
Chrome default styles for HTML5 <figure> includes margin: 1em 40px;
global.html5.css not included on nchembio so including this here
*/
figure {
    margin: 0;
}
div.figure {
	clear: both;
	margin: 0 0 19px;
}
div.figure span.legend {
	display: block;
	margin: -3px 0 0;
	padding: 3px 0;
	color: #111;
}
div.fig-box span.legend {
	margin-bottom:10px;
}
div.figure span.subLegend {
	font-weight:normal;
	display:block;
}

div.restrict-width a.fig-link {
    float:left;
    margin:0 10px 10px 0;
}

div.figure-content {
	margin: 0; padding: 17px 10px 20px;
	border-bottom: 0;
}
div.fig-box div.figure-content {
	background:#FAFAFA;
}
div.box-thumb div.figure-content, div.inline-table div.figure-content {
	border-bottom: 1px solid #e7e7e7;
}
div.no-figure-nav div.figure-content {
	border-bottom: 1px solid #e7e7e7;
	/*margin-bottom: 20px;*/
}
div.figure-content div.description p, 
div.figure-content p.copy {
	font-size: 92%;
	line-height: 1.507em;
	margin: 18px 0;
}
div.figure-content div.description p.credit {
	font-size: 85%;
	font-style: italic;
}
img.fig {
	display: block;
}
img[src*='__chars'] {
	opacity: 0.6; /* ugh images for characters. Reduce opacity to try to make them stand out less from the rest of the text */
}
ul.figure-nav {
	margin: 0; padding: 0 20px;
	border: 1px solid #e7e7e7;
	border-top: 0;
	background: url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
	font-size: 85%;
	position: relative;
}
body.ie6 ul.figure-nav {
	margin-left: 2px;
}
body.ie6 div.related-content ul.figure-nav {
	margin-left: 0;
}


ul.figure-nav li {
	margin: 0 auto;
}
ul.figure-nav li.prev {
	position: absolute;
	left: 10px; top: 0;
}
ul.figure-nav li.next {
	position: absolute;
	right: 10px; top: 0;
}
ul.figure-nav a {
	margin: 0; 
	padding-top: 0;
	padding-bottom: 0;
	display: block;
	text-align: center;
	font-weight: bold;
}
ul.figure-nav li.index {
	text-align: center;
}
ul.figure-nav li.index a {
	display: inline;
}

ul.figure-nav li.prev a {
	padding-right: 20px;
	border-right: 1px solid #eaeaec;
	text-align: left;
}
ul.figure-nav li.next a {
	padding-left: 20px;
	border-left: 1px solid #eaeaec;
	text-align: right;
}
body.ie6 ul.figure-nav li.index {
	padding: 1px;
}

/*
div.table div.description {
	padding: 0 0 0 110px;
	min-height: 100px;
	background: url(http://www.nature.com/view/images/bg_table.gif) no-repeat 0 0;
}
*/
div.table a.table-link, div.table a.table-link span, a.box-link, a-link span {
	display: block;
}
div.table a.table-link, div.box a.box-link {
	width: 120px;
	padding: 110px 0 0 0;
	background: url(http://www.nature.com/view/images/bg_table.gif) no-repeat 0 0;
	border-bottom: 0;
}
div.table a.table-link span, div.box a.box-link span {
	padding: 0 0 0 25px;
	background: url(http://www.nature.com/view/images/icon_full_figure.gif) no-repeat 2px 50%;
}

.full {
	clear: both;
}
ul.resources {
	margin: 0;
}
#constrain ul.resources a {
	padding: 0 0 0 25px;
	border-bottom: 0;
}
ul.resources .full a {
	background: url(http://www.nature.com/view/images/icon_full_figure.gif) no-repeat 2px 0;
}
ul.resources .slides a {
	background: url(http://www.nature.com/view/images/icon_powerpoint.gif) no-repeat 4px 0;
}
div.figure-related ul.resources {
	margin: 0 5px;
}
#constrain ul.resources li {
	padding: 0; margin: 0;
}


div.figures-at-a-glance {
	margin: 20px 0;
	clear: both;
}
div.figures-at-a-glance h2 {
	margin-bottom: 0;
}

div.figure-browser {
	overflow: hidden;
	position: relative;
}

html.js-enabled div.figure-browser-loading {
	height: 120px;
	position: absolute;
	left: 0; top: 0;
	z-index: 4;
	background: #e1e4e9;
	overflow: hidden;
}
html.js-enabled div.figure-browser-loading img {
	position: absolute;
	left: 50%; top: 50%;
	margin: -16px 0 0 -16px;
}
html.js-enabled div.figure-browser {
	background: #e1e4e9;
	width:100%;
	height: 120px;
}
html.js-enabled div.figure-browser ol {
	visibility: hidden;
}


html.js-enabled div.figure-browser a.nav {
	display: block;
	width: 25px; height: 100px;
	background-color: #ccc;
	position: absolute;
	top: 10px;
	z-index: 3;
}
html.js-enabled div.figure-browser a.nav span,
html.js-enabled div.figure-preview a.nav span {
	display: block;
	width: 1px; height: 1px;
	overflow: hidden;
}
html.js-enabled a.inactive {
	cursor: default;
	opacity: 0.2;
	/* order is important - see http://www.quirksmode.org/css/opacity.html */
	-ms-filter:"progid:DXImageTransform.Microsoft.Alpha(Opacity=20)";
	filter: alpha(opacity=20);
}
html.js-enabled body.ie6 div.figure-preview a.nav span {
	display: none;
}
html.js-enabled div.figure-browser a.left {
	left: 0;
	background: url(http://www.nature.com/view/images/figure_browser_left.gif) no-repeat 0 50%;
}
html.js-enabled div.figure-browser a.right {
	right: 0;
	background: url(http://www.nature.com/view/images/figure_browser_right.gif) no-repeat 0 50%;
}


html.js-enabled div.figure-browser div.masking span.legend, 
html.js-enabled div.figure-browser div.masking div.description,
html.js-enabled div.figure-browser div.masking div.larger {
	display: none;
}


html.js-enabled div.figure-browser div.masking {
	width: auto; height: 120px;
	position: absolute;
	top: 0; left: 0;
	overflow: hidden;
}
html.js-enabled div.figure-browser div.masking ol {
	margin: 0; padding: 0;
	position: absolute;
	top: 0; left: 0;
}
html.js-enabled body.ie8 div.figure-browser div.masking ol {
	top: -20px;
}
html.js-enabled div.figure-browser div.masking li {
	position: absolute;
	top: 0; left: 0;
}

html.js-enabled div.figure-preview {
	position: absolute;
	left: 100px; top: 600px;
	width: 725px;
	display: block;
	background: #fff;
	box-shadow: 5px 5px 10px rgba(0,0,0,0.45);
	-moz-box-shadow: 5px 5px 10px rgba(0,0,0,0.45);
	-webkit-box-shadow: 5px 5px 10px rgba(0,0,0,0.45);
	z-index: 3;
}
html.js-enabled div.figure-preview-highlight {
	border-bottom: 1px solid #999;
	border-right: 1px solid #999;
}
html.js-enabled div.figure-preview span.legend {
	padding: 5px 30px 5px 10px;
	display: block;
	background: #afb8c1 url(http://www.nature.com/view/images/bg_dark_grad.gif) repeat-x 0 0;
	color: #fff;
	position: relative;
}
html.js-enabled div.figure-preview span.legend a {
	color: #fff;
	border-color: #fff;
}
html.js-enabled div.figure-preview button.close {
	position: absolute;
	top: 8px; right: 10px;
} 

 html.js-enabled body.ie6 div.figure-preview button.close {
	position: absolute;
	top: 4px; right: 10px;  
	background-color: #ccc;
	color: #000;
	width: 16px;
	height: auto;
	text-align:centre;
	border: solid 1px #fff;
	font-size:0.9em;    
	font-weight:bold;
	line-height: inherit;    
	vertical-align: top;
	text-indent: 0	;  
	background-image: none;  
	padding: 0 0 0 1px;
}



html.js-enabled div.figure-preview div.fig {
	margin: 20px 20px 10px; padding: 0;
}
html.js-enabled div.figure-preview div.fig img {
	margin: 0;
	display: block;
}
html.js-enabled div.figure-preview div.description {
	padding: 0; margin: 0 20px;
}
html.js-enabled div.figure-preview p.fig-link {
	margin: -10px 0 0 0; padding: 0 0 20px;
	text-align: right;
}
html.js-enabled div.figure-preview p.subLinks {
	text-align:right;
}
html.js-enabled div.figure-preview p.subLinks a {
	margin-left:1.5em;
}






.js-enabled .popup {
	position: absolute;
	left: 0; top: 0;
	z-index: 11; /* needs to be above breadcrumbs */
	display: none;
	max-width: 650px;
	/*background: #f5f6f8;*/
	background: #fff;
	box-shadow: 5px 5px 10px rgba(0,0,0,0.45);
	-moz-box-shadow: 5px 5px 10px rgba(0,0,0,0.45);
	-webkit-box-shadow: 5px 5px 10px rgba(0,0,0,0.45);
}
.js-enabled .popup .arrow {
	position: absolute;
	left: 10px; bottom: -15px;
	width: 50px; height: 15px;
	background: url(http://www.nature.com/view/images/popup_box_arrow_down.png) no-repeat 0 0;
}
.js-enabled .popup div.arrow-top {
	top: -15px;
	background: url(http://www.nature.com/view/images/popup_box_arrow_up.gif) no-repeat 0 100%;
}
.js-enabled body.ie6 .popup .arrow {
	bottom: -16px;
}
.js-enabled body.ie6 .popup div.arrow-top {
	top: -16px;
}
.js-enabled .popup-highlight {
	border-bottom: 1px solid #999;
	border-right: 1px solid #999;
}
.js-enabled .popup-highlight .arrow {
	background-image: url(http://www.nature.com/view/images/popup_box_arrow_down.gif)
}
.js-enabled div.popup-shown {
	display: block;
}
.js-enabled .popup h2 {
	margin: 0;
	float: left;
	padding-right: 20px;
}
.js-enabled button.close {
	width: 15px; height: 13px;
	background: #ccc url(http://www.nature.com/view/images/icon_close.gif) no-repeat 0 0;
	border: 1px solid #fff;
	text-indent: -1000em;
}


.js-enabled .popup button.close {
	position: absolute;
	right: 5px; top: 5px;
}
/* generic popup class for used in ie 6 */
html.js-enabled body.ie6 div.popup-highlight {
	width: 600px;
}
html.js-enabled body.ie6 div.compound-popup {
	width: 150px !important;
}
/* popup used on highlighted items */
html.js-enabled body.ie6 div.highlight-popup {
	width: 300px !important;
}
.js-enabled .popup ul.compound-links {
	margin: 10px 0 0;
}
.js-enabled .popup ul.compound-links a {
	font-size: 85%;
}
 div.content .email{
	display: block;
}
.js-enabled div.content .email{
	display: none;
}
.js-enabled .popup .email {
	display: block;
	margin: -8px 0 8px;
}

#quick-nav {
	margin: 0 0 18px; padding: 5px 9px;
	background: #9bc4e0 url(http://www.nature.com/view/images/bg_quick_nav.gif) repeat-x 0 0;
	color: #fff;
}
#quick-nav ul {
	margin: 0;
	width: 100px;
	float: left;
}
#quick-nav li {
	padding: 4px 0 4px 15px;
}
#quick-nav ul li:first-child {
	padding-top: 8px;
}
#quick-nav ul li:last-child {
	padding-bottom: 8px;
}
#quick-nav ul.journal-nav li {
	padding-left: 0;
	padding-right: 15px;
	background: url(http://www.nature.com/view/images/bg_quick_nav_divider.png) repeat-y 100% 0;
}
#quick-nav ul.journal-nav li:first-child {
	background: url(http://www.nature.com/view/images/bg_quick_nav_divider_top.png) no-repeat 100% 0;
}
#quick-nav ul.journal-nav li:last-child {
	background: url(http://www.nature.com/view/images/bg_quick_nav_divider_bottom.png) no-repeat 100% 100%;
}


#quick-nav a {
	color: #fff;
	font-weight: bold;
	text-decoration: none;
}
#quick-nav a:hover {
	text-decoration: underline;
}
#quick-nav li.rss a {
	padding-left: 20px;
	background: url(http://www.nature.com/view/images/icon_newsfeeds.gif) no-repeat 0 0;
}
#quick-nav img {
	margin: 5px 0;
	width: 65px;
	height: 85px;
	float: right;
}




#citations-box {
	padding: 9px;
	background: #fcfcfd url(http://www.nature.com/view/images/bg_citations_box.gif) no-repeat 100% 100%;
}

#citations-box h2 {
	font-weight: normal;
}
#citations-box ul {
	margin: 0;
}
#citations-box li {
	display: inline;
	padding: 0 5px 0 0;
}

#subscribe-now {
	margin: 18px 0; padding: 0;
}
#subscribe-now img {
	margin: 0; padding: 0;
	display: block;
}

#news-and-views-box {
	padding: 10px 10px 0;
}
#news-and-views-box h3 {
	font-weight: normal;
}

#extranav #news-and-views-box p {
	margin: 3px 0 6px;
}
#extranav #news-and-views-box p.continue {
	margin: 0 0 12px;
	text-align: right;
	font-style: italic;
}




/* sidebar boxes */
#extranav div.box {
	margin: 20px 0;
}
/*
[VIEW-2242]
We need this as when we get two ads in a row we loose the spacing between
*/
#extranav div.ad {
  margin: 20px 0;
}
#extranav div.box h2, 
#extranav div.box h3,
#extranav div.box h4,
#extranav div.box h5,
#extranav div.box p {
	margin: 0;
}

.tab-group-heading {
	padding: 9px;
}
.tab {
	padding: 9px 9px 0;
}

#extranav div.box-padding li {
	margin: 0; padding: 5px 0;
}
div.tab-content ul, div.tab-content ol {
	margin: 0;
}
#extranav div.tab-content div.box-padding li:first-child,
#open-innovation-box div.box-padding li:first-child {
	padding: 15px 0 5px;
}
#extranav div.box div.box-padding li li {
	padding: 0;
}

#extranav .box-footer {
	margin: 0; padding: 2px 9px;
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
	text-align: right;
}
#extranav ul.box-footer li {
	float: left;
}
#extranav ul.box-footer li.last {
	float: right;
}

#extranav div.tab-content div.box-padding {
	padding-top: 0;
	overflow: auto;
}
/*
li.compound-link {
	width: 49%;
	float: left;
	font-size: 91%;
}
li.compound-link.last {
	float: right;
	text-align: right;
}
*/

#protocols-related-research,
#nature-jobs-box, 
#nature-events-box,
#open-innovation-box,
#sponsors-box,
#links-box,
#special-feature-box {
	background: #fff url(http://www.nature.com/view/images/bg_box_grad.gif) repeat-x 0 0
}
#protocols-related-research ul,
#nature-jobs-box ul, 
#nature-events-box ul,
#open-innovation-box ul,
#open-innovation-box dl {
	margin: 0;
}

#nature-events-box h2,
#nature-jobs-box h2 {padding: 9px 9px 0;}

#featured-events-box h2 .type,
#featured-jobs-box h2 .type {display: block;}
#featured-events-box p strong,
#featured-jobs-box p strong {display: block;}
#featured-events-box .box-footer,
#featured-jobs-box .box-footer {text-align: left;}
#featured-events-box .box-footer a,
#featured-jobs-box .box-footer a {
	background: url(http://www.nature.com/view/images/arrow_right_red.gif) no-repeat left 0.75ex;
	color: #d23a01;
	display: block;
	padding-left: 12px;
}
#featured-events-box .box-footer .site,
#featured-jobs-box .box-footer .site {
	color: #444;
	display: block;
}
#open-innovation-box ul.challenge-list img {
	margin: 5px 5px 0 0;
	width: 25px; height: 25px;
	float: left;
}
#open-innovation-box ul.challenge-list dl {
	float: left;
}
#open-innovation-box ul.challenge-list p {
	clear: both;
}
#open-innovation-box dt {
	float: left;
	clear: left;
	padding: 0 0.3em 0 0;
}
#open-innovation-box dd {
	float: left;
	clear: right;
}
body.ie6 #open-innovation-box dd {
	float: none;
}
#open-innovation-box dd.reward {
	font-weight: bold;
}
li.powered {
	position: relative;
	font-size: 91%;
	width: 160px;
	text-align: left;
}
li.powered a {
	position: relative;

}
li.powered img {
	position: absolute;
	left: 3px; top: -45%;
}
#inside-article li.powered {
	font-style: italic;
}
#inside-article-antibodies li.powered a {
	display: block;
}


#sponsors-box {
	padding:10px 10px 0;
}

#sponsors-box li {
	margin-bottom:10px;
	text-align:center;
}
#links-box a {
	display:block;
}

html.js-enabled h2.tab-group-heading {
	margin: 0 0 3px 4px; padding: 0;
}
html.js-enabled div.tab-group {
	position: relative;
}
html.js-enabled div.tab-group div.tab-content {
	border: 1px solid #e7e7e7;
	display: none;
}
html.js-enabled div.tab-group div.active div.tab-content {
	display: block;
}
html.js-enabled div.tab-group h3.tab {
	position: absolute;
	margin: 0; padding: 0;
	z-index: 1;
}
/*
html.js-enabled #extranav div.tab-group div.active h3.tab {
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
}
html.js-enabled div.tab-group h3.tab a:hover {
	border: 0;
	color: #5a758a;
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
}
*/

html.js-enabled div.tab-group div.tab-bar {
	position: absolute;
	left: 0; top: 0;
	width: 100%;
	background: #fff;
	margin: 0; padding: 0;
	border: 0 none;
	border-bottom: 1px solid #e7e7e7;
}
html.js-enabled div.tab-group h3.tab a {
	display: block;
	font-size: 91%;
	color: #fff;
	margin: 0; padding: 3px;
	/*border-left: 1px solid #d6e0e9;
	border-right: 1px solid #d6e0e9;*/
	border-bottom: 1px solid #e7e7e7;
	background: #afb8c1 url(http://www.nature.com/view/images/bg_dark_grad.gif) repeat-x 0 0;
	overflow: hidden;
	white-space: nowrap;
	font-weight: normal;
	text-align: center;
	text-overflow: ellipsis;
	-o-text-overflow: ellipsis;
}
html.js-enabled div.tab-group div.active h3.tab a,
html.js-enabled div.tab-group div.active h3.tab a:hover {
	border: 1px solid #e7e7e7;
	padding: 2px 3px 4px;
	border-bottom: 0 none;
	/*color: #5a758a;*/
	color: #333;
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
	cursor: default;
}
html.js-enabled div.tab-group h3.tab a:hover {
	border: 1px solid #e7e7e7;
	padding: 2px 3px 3px;
	/*color: #5a758a;*/
	color: #333;
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
	text-decoration: none;
}


div.tab-content li span.journal-title {
	padding: 0 5px 0 0;
}
div.tab-content li span.time {
	padding: 0 0 0 7px;
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 0 0.4ex;
}


html.js-enabled #inside-article-compounds ol,
html.js-enabled #inside-article-compounds li {
	margin: 0; padding: 0;
	list-style: none;
}

html.js-enabled #inside-article-compounds li {
	display: none;
}
html.js-enabled #extranav #inside-article-compounds li.active {
	text-align: center;
	margin: 15px 15px 0; padding: 0;
	display: block;
}

html.js-enabled #inside-article-compounds div.tab-content {
	position: relative;
}
html.js-enabled #inside-article-compounds a.compound-nav {
	position: absolute;
	top: 45px;
	width: 24px; height: 25px;
	overflow: hidden;
}
html.js-enabled #inside-article-compounds a.compound-nav span {
	visibility: hidden;
}
html.js-enabled #inside-article-compounds a.compound-nav:hover {
	text-decoration: none;
}
html.js-enabled #inside-article-compounds a.prev {
	left: 0;
	background: url(http://www.nature.com/view/images/arrow_left.gif) no-repeat 50% 50%;
}
html.js-enabled #inside-article-compounds a.prev:hover {
	background-image: url(http://www.nature.com/view/images/arrow_left_dark.gif)
}
html.js-enabled #inside-article-compounds a.next {
	right: 0;
	background: url(http://www.nature.com/view/images/arrow_right.gif) no-repeat 50% 50%;
}
html.js-enabled #inside-article-compounds a.next:hover {
	background-image: url(http://www.nature.com/view/images/arrow_right_dark.gif)
}
html.js-enabled #inside-article-compounds span.index {
	font-weight: bold;
	padding-right: 0.2em;
}
html.js-enabled #inside-article-compounds span.total {
	font-weight: bold;
	padding-left: 0.2em;
	padding-right: 6.2em;
}


div.box ol {
	list-style-position: outside;
	padding: 0 0 0 20px;
}
div.box ol, div.box ol li {
	list-style: decimal;
}
div.box ul li {
	list-style: none;
}



#extranav .toggle, #extranav div.player h2 {
	margin-bottom: 0;
}
div.player div.box {
	margin-top: 0;
}
body.ie6 div.player div.box {
	position: relative;
}
div.player h3 {
	padding: 3px 5px;
	background: #b3b8be url(http://www.nature.com/view/images/bg_dark_grad.gif) repeat-x 0 0;
	color: #fff;	
}
div.player div.description {
	padding: 9px;
}
div.player a.video-link {
	display: block;
	border: 0 none;
	font-weight: bold;
}
div.player object {
	margin: 0 auto;
	display: block;
}
#extranav p.podcast-time {
	margin: 9px 0 !important;
}


#extranav div.ad img, 
#extranav div.ad object,
#extranav div.ad embed,
#extranav div.ad iframe {
	margin: 0;
}
#extranav div.wide-skyscraper {
	background: #f1f2f6;
	text-align: center;
	padding: 10px 0;
	border: 1px solid #e7e7e7;
}

div.content div.ad {
	float: right;
	clear: right;
	margin: 10px 0 10px 10px;
}
div.content div.ad a {
	border-bottom: 0 none;
}

html.js-enabled #edsumm div.full-snippet {
	display: none;
}
#edsumm {
	margin: 20px 0;
}
#edsumm h2 {
	margin: 0; padding: 0;
}
#edsumm h3 {
	padding: 0 9px;
}
#edsumm div.editors-summary {
	margin-top: 0;
	padding-top: 9px;
}
body.ie6 #edsumm div.editors-summary {
	zoom: 1;
}
#edsumm div.full-snippet,
#edsumm div.snippet {
	padding: 0 9px 9px;
}
#edsumm a.toggle-bar, .fig-box a.toggle-bar {
	display: block;
	background: #f1f2f6 url(http://www.nature.com/view/images/arrow_down.gif) no-repeat 50% 50%;
	padding: 2px 0;
	text-align: center;
	border-bottom:0;
}
a.toggle-bar span {
	visibility: hidden;
}

.box-internal a.toggle-bar span {
	visibility: visible;
	padding-right:80px;
}

#edsumm a.collapse, .fig-box a.collapse {
	background-image: url(http://www.nature.com/view/images/arrow_up.gif);
}

#edsumm a.toggle-bar:hover, .fig-box a.toggle-bar:hover {
	background-image: url(http://www.nature.com/view/images/arrow_down_dark.gif);
	text-decoration: none;
	border:0;
}
#edsumm a.collapse:hover, .fig-box a.collapse:hover {
	background-image: url(http://www.nature.com/view/images/arrow_up_dark.gif);
}


/* need to make sure this doesn't conflict with the top content sidebar box */
ul.tabs {
	position: relative;
	bottom: -1px; left: 1px;
	z-index: 1;
	zoom: 1;
}
body.ie6 ul.tabs {
	left: 0;
}
body.ie6 ul.tabs li {
	margin-left: 0;
}
ul.tabs li {
	float: left;
	border: 1px solid #e7e7e7;
	margin-left: -1px;
}
ul.tabs li.active {
	border-bottom: 0;
}
ul.tabs li a {
	display: block;
	padding: 5px 10px;
	background: #afb8c1 url(http://www.nature.com/view/images/bg_dark_grad.gif) repeat-x 0 0;
	color: #fff;
}
ul.tabs li a:hover {
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
	color: #333;
	text-decoration: none;
}
ul.tabs li span {
	display: block;
	padding: 5px 10px 6px;
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
	font-weight: bold;
}

div.tab-pane {
	clear: both;
	padding: 19px 0 0;
	margin: 0;
}
div.tab-pane .box-footer {
	margin: 0; padding: 2px 19px;
	background: #fff url(http://www.nature.com/view/images/bg_light_grad.gif) repeat-x 0 0;
	font-size: 85%;
	position: relative;
}
div.tab-pane ul.box-footer li {
	margin: 0 auto;
}
div.tab-pane ul.box-footer li.prev {
	position: absolute;
	left: 10px; top: 0;
}
div.tab-pane ul.box-footer li.next {
	position: absolute;
	right: 10px; top: 0;
}
li.paging {
 	text-align: center;
}
li.paging ol.pagination {
	display: inline
}
li.paging ol.pagination li {
	display: inline;
	padding: 0 0.3em;
}

div.tab-pane p.error {
	margin: 0 0 20px;
	padding: 0 19px;
} 
div.tab-pane li span.journal-title {
	padding: 0 5px 0 0;
}
div.tab-pane li span.time {
	padding: 0 0 0 7px;
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 0 0.4ex;
}
/*
[VIEW-2313]
Adding in a little bit of styling for supplier info
*/
div.tab-pane p.supplier {
    margin: 19px;
    font-style: italic;
}
div.tab-pane p.supplier img {
    vertical-align: middle;
    padding-left: 5px;
}

div.related-content ul.tabs{
	margin-top:20px;
}


#content-list {
	list-style: decimal;
	padding: 0 19px 0 39px;
}
#content-list li {
	list-style: decimal;
}

#content-list h2, #content-list p {
	margin: 0;
}
#content-list li {
	margin: 0 0 20px;
}




div.box ol.fig-tab-index {
	margin: 0; padding: 0;
	list-style-type: none;
}
div.box ol.fig-tab-index li {
	list-style-type: none;
}
ol.fig-tab-index li {
	margin: 20px 0 10px;
}
ol.fig-tab-index li:first-child {
	margin-top: 20px;`
}
h2:first-child + ol.fig-tab-index li:first-child {
	margin-top: 10px;
}
ol.fig-tab-index a.fig-link {
	display: block;
	width: 250px;
	float: left;
	text-align: right;
	margin-right:20px;
}
body.ie6 ol.fig-tab-index a.fig-link {
	margin-left: -135px;
}
ol.fig-tab-index .full {
	clear: none;
}
#content ol.fig-tab-index h3, 
#content ol.fig-tab-index h4,
#content ol.fig-tab-index p {
	margin: 0;
}
div.compound-details {
	width: 600px;
	overflow: auto;
	float: left;
}
div.compound-links {
	font-size: 85%;
}
#content div.compound-links ul.downloads li {
	float: left;
	margin: 0; padding: 0 0.5em;
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 0 0.7ex;
}
#content div.compound-links ul.downloads li.first {
	padding-left: 0;
	background-image: none;
}

.syn-proc span.i {
	font-weight:normal;
	font-style:italic;
}

.syn-proc p {
	margin:10px 0;
}


/* focus styles:
 * Note no #content used - this enables re-use of #toc styles in 
 * #article pages by wrapping content in <div id="toc">
 */
/* focus/supplement anchor list */

ul.focsup-anchor {
	list-style-type: none;
	margin: 0; padding: 0;
}

ul.focsup-anchor ul {
	list-style-type: none;
	margin: 0; padding: 0;
}

ul.focsup-anchor .right, ul.focsup-anchor .left {
	width:48%;
	background:transparent;
} 

ul.focsup-anchor .right {float:right;}

ul.focsup-anchor a, ul.focsup-anchor .text {
	display:block;
	font-weight:bold;
	padding:2px 0 2px 12px;
	zoom: 1;
}
ul.focsup-anchor .text {
	background: url(http://www.nature.com/view/images/arrow_small_right.gif) no-repeat left;
	color:#c03;
}

ul.focsup-anchor a {background:url(http://www.nature.com/view/images/arrow_small_right.gif) no-repeat 0 50%;}
ul.focsup-anchor li.out a {background:url(http://www.nature.com/view/images/arrow_small_right.gif) no-repeat 0 50%;}
ul.focsup-anchor .selected a {
	background-image: url(http://www.nature.com/view/images/arrow_small_down.gif)!important;
	color: #c03;
	text-decoration:none;
}

.focsup-anchor.in-page {
	margin-top:40px;
	padding-top:10px;
	border-top:1px solid #e7e7e7;
}
/* end focus/supplement anchor list */

#toc {
	clear: both;
}
#toc .focus-title {
	color: #5c5c5c;
	font-weight: bold;
	margin-bottom:0;
	margin-top:10px;
	padding: 12px 7px 5px;
}

#toc div.issue.foc {
	background: #fff url(http://www.nature.com/view/images/gradient_vert_grey.jpg) repeat-x top;
	border: 1px solid #dfdfdf;
	margin: 0 0 20px; padding: 0;
	zoom: 1;
}

#toc div.issue.foc div.issue-links {
	height: 100%;
	margin-left:0;
	margin-top:0;
	padding:10px 0 20px 158px;
}

#toc .issue.foc dl.issue {
	margin: 0 0 5px;
}

#toc .issue.foc dl.issue dt {display:inline;}
#toc .issue.foc dl.issue dd {
	display:inline;
	padding:0;
	margin:0;
}

/* end focus styles */


/* cc licenses */
p.license {
	margin-top: 20px;
}
a.cc-license {
	display: block;
	width: 88px; height: 31px;
	background: url(http://www.nature.com/view/images/icon_by_nc_sa.png) no-repeat 0 0;
	text-indent: -999em;
	float: left;
	margin: 5px 0 0 0;
	padding: 0 0.5em 0 0;
}
a.by-nc-nd {
	background-image: url(http://www.nature.com/view/images/icon_by_nc_nd.png);
}

span.open-access {
	padding-left: 1em;
	text-transform: uppercase;
	color: #f5821f;
}



#get-flash {
	margin: 20px 0;
	width: 40%;
}
#get-flash h2, #get-flash p {
	margin: 0;
}
#get-flash a.fp-link {
	display: block;
	padding: 8px 0 8px 40px;
	background: url(http://www.nature.com/view/images/icon_flash.gif) no-repeat 0 50%;
}
/*
[VIEW-2166]
Adding in an extra video box for video template pages that require it
*/
div.videoMeta {
    margin: 20px 0;
    float: right;
    width: 58%;
}
div.videoMeta h2 {
    margin: 0;
}
div.related-content div.video-box {
	clear: both;
	overflow: hidden;
	
}
.ie6 div.related-content div.video-box,
.ie7 div.related-content div.video-box {
    zoom: 1;
}


ul.sponsor-list li {
	padding: 0;
	border: 1px solid #e7e7e7;
}
ul.sponsor-list img {
	display: block;
}
ul.sponsor-list .sponsor-logo {
	display: block;
	width: 84px;
	margin: 0 9px 0 0;
	float: left;
}
ul.sponsor-list .sponsor-text {
	display: block;
	width: 200px;
	margin: 3px 0 0 0;
	float: left;
}

/* Send to a friend content */

body.send-to-a-friend #constrain-content {
	padding-right: 0;
}

body.send-to-a-friend p.article-type {
    float:none;
}

/* Form Layout */

form.main {
	padding: 2em;
	border: solid 1px #000;
	background: #FAFAFA;
	margin-top: 20px;
}

form.main fieldset {
	margin-bottom: 2em;
}

form.main fieldset legend {
	font-weight: bold;
	display: block;
	width: 100%;
	border-bottom: solid 1px #000;
}

form.main fieldset p {
	margin: 0;
	padding: 2em 0 0 0;
}

form.main fieldset p label {
	width: 200px;
	float: left;
	font-weight: bold;
	text-align: right;
}

form.main fieldset p label em {
	display: block;
	font-weight: normal;
	margin: 0;
	font-size: 0.8em;
}

form.main fieldset p span.input {
	display: block;
	margin-left: 220px;
	padding-right: 5px;
}

form.main fieldset p span.input input.text,
form.main fieldset p span.input textarea {
	width: 100%;
	display: block;
	-webkit-appearance: textfield;
	-moz-appearance: textfield;
}

form.main  p span.input textarea {
	height: 7em;
	resize: vertical;
}

form.main blockquote.disclaimer {
	margin: 2em 0;
}

form.main blockquote.disclaimer p {
	margin: 0;
}

form.main p.buttons {
	margin: 2em 0 0;
	text-align: right;
}

div.error {
	background:#fac7c7;
	padding:2em;
}

ul.error {
	padding-left:20px;
	margin-bottom:0;
}
ul.error li {
	list-style-type:disc;
}

/* advertising features */

div.advertising-feature{
	background: url("/view/images/bg_box_grad.gif") repeat-x scroll 0 0 #FFFFFF;
	padding:1em;
	border:1px solid #E7E7E7;
}
div.advertising-feature .ad-feature{
	color:#CC0000;
	font-weight:bold;
	text-transform: uppercase;
}
div.disclaimer p{
	font-style: italic;
}
div.disclaimer h1{
	font-size:116%;
	letter-spacing:-0.5px;
	margin:18px 0 0;
	padding:2px 0;
}
div.branding-logo {
	width: 100%;
	clear: both;
	float: left;
	margin-bottom: 10px;
	overflow: hidden;
}
body.ie6 div.branding-logo,
body.ie7 div.branding-logo {
	padding-top: 20px;
}

div.branding-logo {
	width: 100%;
	clear: both;
	float: left;
	margin-bottom: 10px;
}

div.branding-logo {
	width: 100%;
	clear: both;
	float: left;
	margin-bottom: 10px;
}

/* Subscription CTAs */
.preview-cta{
	border-top:3px double #A2A7AB;
	text-align:center;
	
}
.preview-cta p{
	text-transform:uppercase;
	font-weight:bold;
	display:block;
	background-color:#fff;
	width:140px;
	margin:-8px auto 20px auto;
}
body.ie6 .preview-cta,
body.ie7 .preview-cta,
body.ie8 .preview-cta{
	height:50px;
}
body.ie6 .preview-cta p{
	margin-left:-70px;
	position:absolute;
	width:150px;
}

body.ie8 .preview-cta p{
	position:absolute;
	width:150px;
	margin-left:38%;
}
.preview-cta p a{
	text-transform:lowercase;
	display:block;
	font-size:85%;
	background: url("/view/images/arrow_small_right.gif") no-repeat scroll 100% 50% transparent;
	padding-right: 10px;
}
.society-box {
	overflow: hidden;
	margin-bottom: 20px;
}
.society-box img {
	float: left;
	padding-right: 10px;
}
p.society-login span.journalname {
	font-style: italic;
}
.subscribe-prompt{
	background-color:#fff;
	padding:1.5em 0.5em 1em 1em;
	clear:both;
	margin:2em 0;
	border:1px solid #A2A7AB;
}
.subscribe-prompt .subscribe-cta{
	font-weight:bold;
	overflow:hidden;
	padding: 0 0 35px 30px;
	position: relative;
}
.subscribe-prompt .subscribe-cta .login-prompt a{
	margin-top:26px;
}
.subscribe-prompt .subscribe-cta li{
	text-align:center;
	width:125px;
	padding:0 0.5em;
	float: left;
}
.subscribe-prompt .price,
.subscribe-prompt ul.subscribe-cta a{
	display:block;
}
.subscribe-prompt .price{
	color:#7b7b7b;
	font-size:1.3em;
	font-weight:bold;
}
.subscribe-prompt h4{
	min-height:85px;
	display:block;
	margin:0;
	padding-bottom: 0.5em;
}
.subscribe-prompt .subscribe-cta a{
	font-size:0.8em;
}
.subscribe-prompt .subscribe-cta a.button{
	background:#999 url("/view/images/button-bg.gif") top center no-repeat;
	width:96px;
	color:#000;
	font-size:1em;
	padding:0.3em 0;
	border:1px solid #747474;
	border-radius:3px;
	-moz-border-radius: 3px;
	-webkit-border-radius: 3px;
	margin: 0 0 0 1em;
	position: absolute;
	bottom: 0;
}
.ie7 .subscribe-prompt .subscribe-cta a.button {
	margin-left: -50px;
}
.subscribe-prompt .access-options,
.subscribe-prompt #document-delivery{
	padding:0;
	margin:0;
	line-height: 86%;
}
.subscribe-prompt .access-options .deep-dyve{
	display:none;
}
.subscribe-prompt .access-options li,
.subscribe-prompt #document-delivery li{
	display:inline;
	border-left:1px solid #666;
	font-size:0.8em;
	padding:0 0.4em 0 0.6em;
	margin:0;
}
.subscribe-prompt .access-options .first,
.subscribe-prompt #document-delivery .first{
	border:none;
	padding-left:0;
}
.subscribe-prompt .access-options .last,
.subscribe-prompt #document-delivery .last{
	padding-right:0;
}
.subscribe-prompt .access-options li a,
.subscribe-prompt #document-delivery li a{
	font-weight:normal;
}
div.subscribe-prompt h2{	
	color:#A1AEB7;
	font-size:85%;
	float:left;
	width:150px;
	line-height:1.4em;
	text-transform:uppercase;
	margin:0;
}
.subscribe-prompt .prompt{
	font-size: 120%;
	width: 150px;
	float:left;
}
.subscribe-prompt h3{
	clear:both;
	padding:0;
	margin:0;
	font-size:0.85em;
}

ul.link-group li.title {
	font-weight: bold;
	font-size: 110%;
	margin-top: 20px;
}

ul.link-group-sub {
	margin: 0 0 20px 10px;
}

ul.link-group-sub li.title {
	font-size: 100%;
	margin-top: 0;
}

ul.link-group li a {
	border :0;
}

/* Bean Data */

#bakedbean {
	width: 100%;
	color: #fff;
	left: 0;
	top: 0;
}

#bakedbean a {
	display:none;
}

.js-enabled #bakedbean a {
	display:block;
	float:left;
	margin-left: 10%;
	background:#34352e;
	-webkit-border-bottom-right-radius: 20px;
	-webkit-border-bottom-left-radius: 20px;
	-moz-border-radius-bottomright: 20px;
	-moz-border-radius-bottomleft: 20px;
	border-bottom-right-radius: 20px;
	border-bottom-left-radius: 20px;
	padding: 5px 15px;
	color:#fff;
}

#bakedbean .inner {
	background: #34352e;
	float:left;
	width:100%;
}

#bakedbean .bean {
	width:22%;
	float:left;
	padding: 20px;
	overflow:auto;
}

#bakedbean .bean strong {
	font-weight: bold;
	font-size: 120%;
	width:100%;
	display:block;
	color: #F92672;
	border-bottom:2px solid #fff;
	margin-bottom:10px;
}

#bakedbean .bean span {
	white-space: pre;
}

.js-enabled #bakedbean .inner {
	display:none;
}


/* captcha box styles */
div.captcha-box {
	clear:both;
	margin-top:2em;
}

div.captcha-box label {
	float: left;
	width: 100px;
	
}

#content div.captcha-box div {
	padding: 0;
	margin: 0;
}

div.captcha-box .recaptcha_input_area {
	line-height: 1.5em;
}

div.captcha-box .recaptchatable td img {
	display: inline;
}

div.captcha-box .recaptchatable {
	line-height:0;
}

div.captcha-box iframe {
	width: 100%;
	height: 260px;
	border: 0;
}



/* Special feature box */
#special-feature-box h3 {
	color: inherit;
	margin-bottom:1em;
}

#extranav #special-feature-box h3.special-title {
	font-size: 108%;
	margin-bottom:0.5em;
}

#special-feature-box a h3:hover {
	text-decoration:underline;
}

#special-feature-box img.header {
	width:280px;
}


#special-feature-box .feature-list, #special-feature-box .feature-list li {
	float:left;
}

#special-feature-box .feature-list span.authors {
	font-size:85%;
}

#special-feature-box .feature-a img {
	width:80px;
	float:left;
	margin-right:10px;
}

#special-feature-box .feature-a, #special-feature-box .feature-a li {
	width:100%;
}

#special-feature-box .feature-a {
	float:none;
}

#special-feature-box .feature-b img {
	width:80px;
	float: left;
}

#special-feature-box .feature-b span.authors {
	padding-left:90px;
	display:block;
}

#special-feature-box ul.feature-c li {
	width:120px;
	padding:5px 15px 10px 0;
}

#special-feature-box ul.feature-c li.right {
	float:right;
	padding:5px 0 10px 15px;
}

#special-feature-box .feature-b p, #special-feature-box .feature-b h3 {
	padding-left:90px;
}

#special-feature-box .feature-b .no-image p, #special-feature-box .feature-b .no-image h3, #special-feature-box .feature-b .no-image span {
	padding-left: 0;
}

#special-feature-box .box-footer {
	clear:both;
}

body.ie7 #special-feature-box .feature-b li {
	padding-right: 9px;
}



#author-contact {
	clear: both;
}

#author-contact input.txt, #author-contact textarea {
	margin: 2px 0; padding: 3px;
	border: 1px solid #ccc;
}
#author-contact input.txt {
	width: 300px;
}
#author-contact textarea {
	width: 100%; height: 100px;
}
#author-contact-copy {
	margin: 8px 0 0;
}
#author-contact label {
	margin: 0; padding: 4px 0;
	width: 80px;
	display: block;
	float: left;
	clear: left;
}
#author-contact #author-contact-message-label {
	clear:both;
	width: 100%;
	padding-bottom: 0;
}
#author-contact span.legend {
	display: block;
	padding-bottom: 10px;
}

#author-contact input.txt:focus, #author-contact textarea:focus {
	border: 2px solid #999;
	padding: 2px;
}
#author-contact #author-contact-copy, #author-contact #author-contact-copy-label {
	float: right;
}
#author-contact #author-contact-copy-label {
	width: auto;
	padding-left: 5px;
}
#author-contact button {
	background: #fff url(http://www.nature.com/view/images/bg_button.gif) repeat-x 0 100%;
	border: 1px solid #e7e7e7;
	margin: 0; padding: 2px 15px;
	float: left;
	overflow: visible;
	cursor: pointer;
	color: #58626b;
}
#author-contact button:hover {
	color: #000;
	border: 1px solid #999;
}

input[readonly] {
	color: #999;
}


dl.confirm-message dt {
	margin-top: 20px;
	font-weight: bold;
}

/* Shopping cart */


#popUpShoppingBasket_link {
	padding: .4em 1em .4em 20px;
	text-decoration: none;
	position: relative;
}
#popUpShoppingBasket_link span.ui-icon {
	margin: 0 5px 0 0;
	position: absolute;
	left: .2em;
	top: 50%;
	margin-top: -8px;
}

/* Overwrite default jquery ui themes */
.popUpShoppingBasket_dialog .ui-widget-header,
.popUpCountry_dialog .ui-widget-header{
    background: none;
    border: 0;
}

.popUpShoppingBasket_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close.ui-state-hover,
.popUpCountry_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close.ui-state-hover,
.popUpShoppingBasket_dialog .ui-dialog-titlebar,
.popUpShoppingBasket_dialog.ui-corner-all,
.popUpCountry_dialog.ui-corner-all {
    -moz-border-radius: 0;
    -webkit-border-radius: 0;
    border-radius: 0;

}
/* end of theme overwrites */

/* Dialog L & F */
.popUpShoppingBasket_dialog,
.popUpCountry_dialog {
    padding:0.2em 0 0 0;
    background-color: #dcdcdc;
    border-color: #d0d0d1;
    /* shadow*/
	-moz-box-shadow: 3px 3px 4px #999;
	-webkit-box-shadow: 3px 3px 4px #999;
	box-shadow: 3px 3px 4px #999;
	/* For IE 8 */
	-ms-filter: "progid:DXImageTransform.Microsoft.Shadow(Strength=4, Direction=135, Color='#999')";
	/* For IE 5.5 - 7 */
	/*filter: progid:DXImageTransform.Microsoft.Shadow(Strength=1, Direction=130, Color='#eee');*/
}
body.ie6 .popUpShoppingBasket_dialog,
body.ie6 .popUpCountry_dialog,
body.ie7 .popUpShoppingBasket_dialog,
body.ie7 .popUpCountry_dialog{
	border:2px solid #999;
}
.popUpShoppingBasket_dialog .ui-dialog-titlebar {
    padding-top: 1em;
    border-bottom: 1px solid #e7e7e7;
    /* gradient */
    /* Firefox 3.6 */
	background-image: -moz-linear-gradient(top, #dadadb, #f3f3f4); 
	/* Safari & Chrome */
	background-image: -webkit-gradient(linear,left bottom,left top,color-stop(0, #f3f3f4),color-stop(1, #dadadb)); 
    /* IE6 & IE7 */                	
	filter:  progid:DXImageTransform.Microsoft.gradient(GradientType=0,startColorstr='#dadadb', endColorstr='#f3f3f4'); 
    /* IE8 */
	-ms-filter: "progid:DXImageTransform.Microsoft.gradient(GradientType=0,startColorstr='#dadadb', endColorstr='#f3f3f4')"; 
}
.popUpCountry_dialog.ui-dialog .ui-dialog-content {
    background-color: #fff;
}

.popUpShoppingBasket_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close,
.popUpCountry_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close {
    float: right;
}
.popUpShoppingBasket_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close {
    margin-top: 10px;
    top: 0;
}
.popUpShoppingBasket_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close span,
.popUpCountry_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close span {
    
	background:#f3f3f4 url("/view/images/close.jpg") no-repeat 0 0;
	display:block;
	text-indent:-9999px;
	height:16px;
	width:17px;
	margin-right:20px;
}

.popUpShoppingBasket_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close.ui-state-hover,
.popUpCountry_dialog .ui-dialog-titlebar a.ui-dialog-titlebar-close.ui-state-hover {
    /* gradient */
    /* Firefox 3.6 */                    
   /* background-image: -moz-linear-gradient(top, #f6f9fe, #d8dcdf); *//*
    /* Safari & Chrome */
 /*   background-image: -webkit-gradient(linear,left bottom,left top,color-stop(0, #d8dcdf),color-stop(1, #f6f9fe)); */
    /* IE6 & IE7 */    
  /*  filter:  progid:DXImageTransform.Microsoft.gradient(GradientType=0,startColorstr='#f6f9fe', endColorstr='#d8dcdf'); */
    /* IE8 */                    
  /*  -ms-filter: "progid:DXImageTransform.Microsoft.gradient(GradientType=0,startColorstr='#f6f9fe', endColorstr='#d8dcdf')"; */
}
.popUpShoppingBasket_dialog.ui-dialog .ui-dialog-buttonpane,
.popUpCountry_dialog.ui-dialog .ui-dialog-buttonpane {
    border: 0;
    margin: 0;
    padding: 1em 2em;
    background-color: #fff;
	overflow: auto;
}
#popUpShoppingBasket_Continue_btn span {
    padding: 0;
}

.popUpShoppingBasket_dialog .ui-button,
.popUpCountry_dialog .ui-button {
    padding: 0;
}
/* end of dialog L & F */
/* shopping basket dialog content */
#ui-dialog-title-popUpShoppingBasket {
    padding: 0.5em 0.5em 0.3em;
}

#popUpShoppingBasket{
    padding: 0; 
    background-color: #fff;                   
}

#popUpShoppingBasket table {
    width: 100%;
}
#popUpShoppingBasket table td {
    padding: 0 1em 1em 0;
    vertical-align: top;
}
#popUpShoppingBasket table td p{
	padding:0;
	margin:0;
	line-height:1.2em;
}
#popUpShoppingBasket table tbody
{
    margin: 1em;
}

#popUpShoppingBasket thead,
#popUpShoppingBasket table caption {
    position:absolute;
    text-indent: -999em;
}

#popUpShoppingBasket tfoot td p{
    float:left;
}
#popUpShoppingBasket tfoot td {
    border: 1px dashed #7c8284;
    border-width: 1px 0;
	vertical-align:middle;
	padding-top:0.7em;
	padding-bottom:0.5em;
}
#popUpShoppingBasket tfoot tr {
    margin: 0;
}

#popUpShoppingBasket tr {
    margin: 1em 0 2em 0;
}

#popUpShoppingBasket .shoppingItemRemove {
    border: 0;
    background: none;
    padding:0;
    cursor: pointer;
    cursor: hand;  			        
}

#popUpShoppingBasket .shoppingItemAction {
    text-align: right;
}

#popUpShoppingBasket tfoot td,
#popUpShoppingBasket .shoppingItemPrice {
    text-align: right;
}

.popUpShoppingBasket_dialog #shoppinglocation {
    padding-left: 2.5em;
    margin: 0em;
    padding-bottom: 1em;
    background: url() no-repeat 0 0;
    clear: both;
    display:block;
}

#popUpShoppingBasket .shoppingBasketContents {
    padding: 1em 2em;
    max-height:15em;
    overflow-y: auto;
}

#popUpShoppingBasket_Continue_btn {
    background: none;
    border: 0;
    float: left;
    padding: 0;
    line-height: auto;
	margin-top:-25px;
	width:90px;
}
body.ie7 #popUpShoppingBasket_Continue_btn,
body.ie6 #popUpShoppingBasket_Continue_btn {
	margin-top:0;
}
/* end shopping basket dialog content */		    
/* popUp country dialog contents */
.popUpCountry_dialog #popUpShoppingBasketCountryList {
    width: 100%;
}

/* end popUp country dialog contents */
/* font styling */
#popUpShoppingBasket a,
#popUpShoppingBasket a:visited,
#popUpShoppingBasket a:hover,
#popUpShoppingBasket a:link,
#popUpShoppingBasket_Continue_btn span,
.popUpShoppingBasket_dialog a,
#popUpShoppingBasket .shoppingItemRemove 
{
    color: #097897;
    text-decoration: none;
}
#popUpShoppingBasket .shoppingItemPrice span {
    color: #444;
}
#popUpShoppingBasket a:hover,
#popUpShoppingBasket input.shoppingItemRemove:hover,
#popUpShoppingBasket_Continue_btn.ui-state-hover span,
.popUpShoppingBasket_dialog #shoppinglocation a:hover{
    text-decoration: underline;
}

#popUpShoppingBasket,
.popUpShoppingBasket_dialog,
#popUpCountry,
.popUpCountry_dialog {
    font-family: Arial;
}
#ui-dialog-title-popUpShoppingBasket{
    font: normal 107% Arial;
	padding-top:3em;
	padding-left:1em;
}
#ui-dialog-title-popUpShoppingBasket {
    font: normal 150% Arial;
}
#popUpShoppingBasket_Continue_btn span {
    font: normal 77% Arial;
}

.popUpShoppingBasket_dialog #shoppinglocation {
    font: normal 77% Arial;
}
#popUpShoppingBasket tfoot strong,
#popUpShoppingBasket p.shoppingItemTitle {
    font-weight: bold;
}
#popUpShoppingBasket td p{
    font-size: 85%;
}
#popUpShoppingBasket tfoot td p{
    font: bold 100% Arial;
}
#popUpShoppingBasket .shoppingItemRemove {
    font: normal 77% Arial;
}
#popUpShoppingBasket .shoppingItemPrice span {
    font: bold 85% Arial;
}
#popUpShoppingBasket tfoot span{
    color: #363636;
    font-size: 77%
}

#popUpCountry,
#popUpCountry select {
    font-size: 85%;
}

.popUpShoppingBasket_dialog .ui-button,
.popUpCountry_dialog .ui-button {
    font: bold 107% Arial;
    color: #000;
	text-align:center;
	clear:both;
	background:#999 url("/view/images/button-bg.gif") top center no-repeat;
	width:141px;
	color:#000;
	font-size:1em;
	padding:0.3em 0;
	border:1px solid #747474;
	border-radius:3px;
	-moz-border-radius: 3px;
	-webkit-border-radius: 3px;
	margin:0.5em 0;
	cursor:pointer;
	float:right;
	font-weight:bold;
}
/* end font styling */

.reshigh-carousel  {
	border:1px solid #E7E7E7;
	position:relative;
	overflow: hidden;
	float:left;
	width:100%;
	margin:20px 0;
}

.no-javascript .reshigh-carousel  {
    padding:10px;
}

.reshigh-carousel.active .container {
	width: 100%;
	margin:0 25px;
}

.reshigh-carousel .container {
	font-size:0.9em;
	height:103px;
	overflow:hidden;
	position:relative;
}

.js-enabled body.ie7 .reshigh-carousel .container ul {
	overflow:hidden;
	position:relative;
	height: 103px;
	margin-bottom:0;
}

.js-enabled .reshigh-carousel .container ul {
	overflow:hidden;
	position:absolute;
	margin-bottom:0;
}

.js-enabled .reshigh-carousel .container ul li {
	float:left;
	position:relative;
	height:108px;
	font-size:0.9em;
}

.no-javascript .reshigh-carousel .container ul li {
    float:left;
    width:33%;
    height:50px;
	
}


.js-enabled .reshigh-carousel .container ul li div {
	border-left:1px solid #E7E7E7;
	padding:2px 5px 0 5px;
	height:71px;
	overflow:hidden;
	margin:15px 0;
}

.reshigh-carousel .container ul li:first-child div {
	border:0;
}

.reshigh-carousel .container ul li div span {
	color:#A1AEB7;
	height:20px;
	display:block;
	text-transform:uppercase;
	overflow:hidden;
}

.reshigh-carousel .container ul li div span.title {
	text-transform:none;
	color:#292929;
	height:auto;
	overflow:hidden;
	font-size:1.2em;
	line-height:1.3em;
	display:block;
	font-weight:bold;
}

.no-javascript .reshigh-carousel .container ul li div span {
    height:auto;
    line-height:normal;
}

.js-enabled .reshigh-carousel .container ul li div a {
	font-weight:bold;
	display:block;
	overflow:hidden;
	font-size:1.2em;
	line-height:1.3em;
	word-wrap:break-word;
}

.no-javascript .reshigh-carousel .container ul li div a {
    display:block;
    font-size:1.2em;
	margin-bottom:10px;
}

.js-enabled .reshigh-carousel .left, .js-enabled .reshigh-carousel .right {
	background:none repeat scroll 0 0 #E7E7E7;
	bottom:1px;
	cursor:pointer;
	left:0;
	position:absolute;
	top:36px;
	width:14px;
	height:30px;
}

.js-enabled .reshigh-carousel .right {
	left:auto;
	right:0;
}

.js-enabled .reshigh-carousel .left span, .js-enabled .reshigh-carousel .right span {
	border-bottom:8px solid transparent;
	border-right:8px solid #494949;
	border-top:8px solid transparent;
	height:0;
	left:50%;
	margin:-8px 0 0 -4px;
	position:absolute;
	top:50%;
}

.js-enabled .reshigh-carousel .right span {
	border-left:8px solid #494949;
	border-right:medium none;
}


/* ICB Compound Viewer */

.js-enabled .icb-box {
	display:block;
	visibility:hidden;
	max-width:none;
}

.js-enabled .icb-box .popup-content {
	width:500px;
	height:100px;
	margin-top:10px;
}

body.ie7 .icb-box .popup-content {
	margin-top:20px;
}

.js-enabled button.grow, .js-enabled button.shrink {
	background:url("/view/images/expand_small.gif") no-repeat scroll top center #CCCCCC;
	border:1px solid #FFFFFF;
	height:13px;
	text-indent:-1000em;
	width:14px;
	position:absolute;
	right:25px;
	top:5px;
}

.js-enabled button.shrink {
	background:url("/view/images/contract_small.gif") no-repeat scroll top center #CCCCCC;
}

.js-enabled .popup .arrow-right {
	right:10px;
	left:auto;
}

.icb-box p {
    margin-bottom:10px;
}

/* global message */

div.global-message.minimised .content {display:none}

.global-message-contain {
	position: relative;
	border-color: #FFFFFF ;
    border-style: solid solid none;
    border-width: 8px 0 0;
	clear:both;
}
.global-message {
	border: 1px solid #aeaeae;
	background: #fbf9d3 url(http://www.nature.com/common/images/survey/main_bg.gif) no-repeat right bottom;
	display: block;
	position: relative;
}

div.global-message.minimised {
	background-image: url(http://www.nature.com/common/images/survey/minimised_bg.gif);
	background-position:right center;
}

div.global-message.minimised .wrapper {
	background: url(http://www.nature.com/common/images/survey/tinyantibody2.jpg) no-repeat 5px 1px;
 	height: 23px;
}

.global-message a {color:#ce0808;}

.global-message .content {
	padding:10px 5px 20px 130px;
	background: url(http://www.nature.com/common/images/survey/antibody4.jpg) no-repeat 5px -20px;
	position: relative;
}

.global-message.no-cookies .content {
	padding:0 5px 0 10px;
	background: transparent;
}

.global-message h1 {
	font-size:120%;
	margin:0 0 10px 0;
	font-weight: bold;
}
.global-message h1 a {
	font-weight: bold;
	border-bottom: 0;
}

div.global-message.minimised h1 {
	position:absolute;
	top:3px;
	left:50px;
	font-size:100%;
	margin:0;
	background: url(http://www.nature.com/common/images/survey/arrow_triple.gif) no-repeat 0 0.7ex;
	padding-left: 17px;
	font-weight: bold;
}

.global-message .content p {
	line-height:1;
    margin-bottom: 1em;
}

.global-message p.action {
	background: url(http://www.nature.com/common/images/survey/button.gif) no-repeat left top;
	font-weight:bold;
	padding:4px 0 9px 25px;
	margin-bottom:0;
}

/* if no images */

div.global-message.no-image .wrapper { background: none; }

div.global-message.no-image .content {
	padding:10px 5px 20px 10px;
	background: none;
}

div.global-message.minimised.no-image h1 {
	left: 5px;
}

/* message control */
.message-control {
	border-top: 1px solid #aeaeae;
	border-left: 1px solid #aeaeae;
	margin:0;
}

.message-control a {
	font-weight:bold;
/*	font-size:80%;*/
	background: #fff url(http://www.nature.com/common/images/survey/arrow_triple.gif) no-repeat 8px 50%;
	padding: 3px 0 4px 25px;
	display:block;
}

body.ie7 .message-control a {
	padding: 1px 0 1px 25px;
	height: 19px;
}


div.global-message.visible .message-control {
	position:absolute;
	bottom:0;
	right:0;
	width:17em;
}

div.global-message.minimised .message-control {
	float:right;
	border-top: 0;
	width:13em;
	background-color: #fff;
}

div.global-message.minimised .message-control a.persistent {
    float: left;
}

div.global-message.minimised a.remove {
    background: none repeat scroll 0 0 transparent;
    border-left: 1px solid #AEAEAE;
    display: block;
    float: right;
    margin: 0 0 0 10px;
    padding: 5px 5px 0;
}

body.ie7 div.global-message.minimised a.remove {
	padding: 2px 5px;
}
body.ie6 div.global-message.minimised a.remove {
	padding: 5px;
}


div.global-message.minimised a.remove img {
	border: 0;
}
.js-enabled .nojava {
	display: none;
}


/* end message control */
/* end global message */


.research-highlight h2.topic,
.research-highlights h2.topic,
.news-in-brief h2.topic,
.methods-in-brief h2.topic,
.tools-in-brief h2.topic {
    margin-bottom:0;
    text-transform:uppercase;
    color:#A1AEB7;
}

.research-highlight .article-type,
.research-highlights .article-type,
.news-in-brief .article-type,
.methods-in-brief .article-type,
.tools-in-brief .article-type {
    margin-bottom:0;
}

div.in-brief h4 {
	margin-bottom: 0;
}

/* Abbreviations */

div.abbreviations {
	margin-top: 20px;
}
div.abbreviations h4, div.abbreviations p {
	display: inline;
}
.aap_statement { border:1px solid #E7E7E7; padding:10px 10px 1px; margin:0 0 10px; }
.aap_statement p { margin:0 0 10px; }

div.intro {
	margin-top: 20px;
}

div.in-brief h4 {
	margin-bottom: 0;
}

/* Abbreviations */

div.abbreviations {
	margin-top: 20px;
}
div.abbreviations h4, div.abbreviations p {
	display: inline;
}

div.title-notes {
	margin-top: 20px;
}

#protocols-related-research span.journal-title {
	padding: 0 5px 0 0;
}

#protocols-related-research span.time {
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 0 0.4ex;
	padding: 0 0 0 7px;
}

.article-template div.related-protocols {
	padding: 19px 19px 0;
}

.article-template ul.related-protocols h3 {
	margin: 0;
}

.article-template ul.related-protocols li {
	margin-bottom: 20px;
}

.article-template ul.related-protocols li p {
	margin: 0;
}

.article-template ul.related-protocols li p span.journal-title {
	padding: 0 5px 0 0;
}

.article-template ul.related-protocols li p span.time {
	background: url(http://www.nature.com/view/images/bg_pipe.gif) no-repeat 0 0.4ex;
	padding: 0 0 0 7px;
}