Volume 81 Issue 6, June 2017

Watson et al. obtained magnetic resonance images of the brains of 10- to 19-year-olds who had undergone the Fontan procedure for single-ventricle defects and compared them with those of healthy controls. They found significant and widespread reduction in regional gray matter. Several surgery-related issues were associated with reduction in volume, suggesting potentially modifiable risk factors. See the article on page 881.