Original Article

Subject Categories: Functional Polymers

Polymer Journal (2015) 47, 206–211; doi:10.1038/pj.2014.122; published online 17 December 2014

Design of molecule-responsive organic–inorganic hybrid nanoparticles bearing cyclodextrin as ligands

Akifumi Kawamura1,2, Tomoya Katoh1, Tadashi Uragami1,2 and Takashi Miyata1,2

  1. 1Department of Chemistry and Materials Engineering, Kansai University, Suita, Osaka, Japan
  2. 2Organization for Research and Development of Innovative Science and Technology (ORDIST), Kansai University, Suita, Osaka, Japan

Correspondence: Professor T Miyata, Department of Chemistry and Materials Engineering, Kansai University, 3-3-35 Yamate-Cho, Suita, Osaka 546-8680, Japan. E-mail: tmiyata@kansai-u.ac.jp

Received 15 October 2014; Revised 10 November 2014; Accepted 10 November 2014
Advance online publication 17 December 2014

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Abstract

Novel organic–inorganic hybrid nanoparticles with a bisphenol A (BPA)-responsive hydrogel layer on the surface of SiO2 nanoparticles were prepared via surface-initiated atom transfer radical polymerization of acrylamide (AAm), acryloyl-modified β-cyclodextrin (CD) and N, N′-methylenebisacrylamide. The resulting CD-PAAm/SiO2 nanoparticles underwent a change in size in response to BPA. The BPA-responsive shrinkage of the CD-PAAm/SiO2 nanoparticles was caused by an increase in the crosslinking density of the CD-PAAm hydrogel layer, which resulted from the formation of CD-BPA-CD complexes acting as dynamic crosslinks. The smart functions of BPA-responsive organic–inorganic hybrid nanoparticles can provide useful tools for constructing molecular sensors and adsorption materials.