Retinal vascular caliber analysis is useful in the prediction of CHD mortality
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A number of studies have indicated that microvascular disease might be a more important factor in the development of coronary heart disease (CHD) in women than in men. Photographs of the retinal microvasculature provide a noninvasive method for evaluating the condition of the microcirculation. Using this technique, the relationship between retinal vascular caliber and CHD-related death was examined in a population-based prospective study comprising 1,884 women and 1,456 men, aged 49 years or more, living in two postcode areas in New South Wales, Australia. In addition to stereoscopic retinal photographs, baseline measurements of height, weight, and blood pressure were taken for each participant. Pre-existing CHD or diabetes was also recorded. Mean arteriolar and vascular caliber measurements were taken from baseline photographs, and arteriole-to-venule ratio calculated.
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